ID   F199X_MOUSE             Reviewed;         388 AA.
AC   Q8K2D0; B1AZH1; Q3U3R2;
DT   03-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2002, sequence version 1.
DT   03-AUG-2022, entry version 103.
DE   RecName: Full=Protein FAM199X;
GN   Name=Fam199x;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=C57BL/6J, and NOD; TISSUE=Dendritic cell, and Spinal cord;
RX   PubMed=16141072; DOI=10.1126/science.1112014;
RA   Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA   Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA   Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA   Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA   Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA   Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA   Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA   Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA   Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA   Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA   Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA   Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA   Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA   Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA   Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA   Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA   Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA   Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA   Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA   Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA   Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA   Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA   Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA   Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA   Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA   van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA   Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA   Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA   Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA   Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA   Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA   Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA   Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA   Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT   "The transcriptional landscape of the mammalian genome.";
RL   Science 309:1559-1563(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J;
RX   PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA   Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA   Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA   Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA   Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA   Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA   Eichler E.E., Ponting C.P.;
RT   "Lineage-specific biology revealed by a finished genome assembly of the
RT   mouse.";
RL   PLoS Biol. 7:E1000112-E1000112(2009).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=FVB/N; TISSUE=Mammary tumor;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SIMILARITY: Belongs to the FAM199 family. {ECO:0000305}.
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DR   EMBL; AK039695; BAC30420.1; -; mRNA.
DR   EMBL; AK154624; BAE32723.1; -; mRNA.
DR   EMBL; AL954296; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BC031748; AAH31748.1; -; mRNA.
DR   CCDS; CCDS30428.1; -.
DR   RefSeq; NP_666373.1; NM_146261.2.
DR   AlphaFoldDB; Q8K2D0; -.
DR   SMR; Q8K2D0; -.
DR   BioGRID; 232814; 4.
DR   STRING; 10090.ENSMUSP00000045544; -.
DR   iPTMnet; Q8K2D0; -.
DR   PhosphoSitePlus; Q8K2D0; -.
DR   MaxQB; Q8K2D0; -.
DR   PaxDb; Q8K2D0; -.
DR   PRIDE; Q8K2D0; -.
DR   ProteomicsDB; 275723; -.
DR   Antibodypedia; 512; 13 antibodies from 8 providers.
DR   DNASU; 245622; -.
DR   Ensembl; ENSMUST00000047852; ENSMUSP00000045544; ENSMUSG00000042595.
DR   GeneID; 245622; -.
DR   KEGG; mmu:245622; -.
DR   UCSC; uc009ujq.2; mouse.
DR   CTD; 139231; -.
DR   MGI; MGI:2384304; Fam199x.
DR   VEuPathDB; HostDB:ENSMUSG00000042595; -.
DR   eggNOG; ENOG502QR59; Eukaryota.
DR   GeneTree; ENSGT00440000033895; -.
DR   HOGENOM; CLU_061935_0_0_1; -.
DR   InParanoid; Q8K2D0; -.
DR   OMA; NCGSTSG; -.
DR   OrthoDB; 1137076at2759; -.
DR   PhylomeDB; Q8K2D0; -.
DR   BioGRID-ORCS; 245622; 2 hits in 71 CRISPR screens.
DR   ChiTaRS; Fam199x; mouse.
DR   PRO; PR:Q8K2D0; -.
DR   Proteomes; UP000000589; Chromosome X.
DR   RNAct; Q8K2D0; protein.
DR   Bgee; ENSMUSG00000042595; Expressed in optic fissure and 229 other tissues.
DR   Genevisible; Q8K2D0; MM.
DR   InterPro; IPR029672; FAM199X_fam.
DR   PANTHER; PTHR32003; PTHR32003; 1.
DR   Pfam; PF15814; FAM199X; 1.
PE   2: Evidence at transcript level;
KW   Phosphoprotein; Reference proteome.
FT   CHAIN           1..388
FT                   /note="Protein FAM199X"
FT                   /id="PRO_0000251211"
FT   REGION          288..358
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        288..325
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         316
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q6PEV8"
FT   MOD_RES         321
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q6PEV8"
FT   CONFLICT        301
FT                   /note="G -> E (in Ref. 1; BAE32723)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   388 AA;  42839 MW;  D3A6B9DBEBBD4AEA CRC64;
     MSDEASATTS YEKFLTPEEP FPFLGAPRGV GTCPSEEPGC LDISDFGCQL SSCHRTDPLH
     RFHTNRWNLT SCGTSVASSE CSEELFSSVS VGDQDDCYSL LDDQDFTSFD LFPEGSVCSD
     VSSSISTYWD WSDSEFEWQL PGSDIASGSD VLSDVIPSIP SSPCLVSKKK NKHRNLDELA
     WSAMTNDEQV EYIEYLSRKV STEMGLREQL DIIKIIDPSA QISPTDSEFI IELNCLTDEK
     LKQVRNYIKE HSLRQRPTRE AWKRSNFSCA STSGVSGASA SASSSSASMV SSASSSGSSV
     GNSASNSSAN MSRAHSDSNL SASAAERIRD SKKRSKQRKL QQKAFRKRQL KEQRQARKER
     LSGLFLNEEV LSLKVTEEDH EADVDVLM