ID   F200A_MACFA             Reviewed;         573 AA.
AC   Q4R6P1;
DT   06-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2005, sequence version 1.
DT   25-MAY-2022, entry version 50.
DE   RecName: Full=Protein FAM200A;
GN   Name=FAM200A; ORFNames=QtsA-17507;
OS   Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9541;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RG   International consortium for macaque cDNA sequencing and analysis;
RT   "DNA sequences of macaque genes expressed in brain or testis and its
RT   evolutionary implications.";
RL   Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the FAM200 family. {ECO:0000305}.
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DR   EMBL; AB169141; BAE01234.1; -; mRNA.
DR   RefSeq; NP_001270512.1; NM_001283583.1.
DR   RefSeq; XP_005549254.1; XM_005549197.2.
DR   RefSeq; XP_005549255.1; XM_005549198.2.
DR   RefSeq; XP_005549256.1; XM_005549199.2.
DR   AlphaFoldDB; Q4R6P1; -.
DR   STRING; 9541.XP_005549253.1; -.
DR   PRIDE; Q4R6P1; -.
DR   GeneID; 101926726; -.
DR   KEGG; mcf:101926726; -.
DR   CTD; 221786; -.
DR   VEuPathDB; HostDB:ENSMFAG00000030317; -.
DR   eggNOG; ENOG502SICS; Eukaryota.
DR   OMA; NCKGISS; -.
DR   OrthoDB; 875619at2759; -.
DR   Proteomes; UP000233100; Chromosome 3.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   SUPFAM; SSF53098; SSF53098; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..573
FT                   /note="Protein FAM200A"
FT                   /id="PRO_0000279406"
FT   TOPO_DOM        1..513
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        514..533
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        534..573
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   REGION          1..51
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..15
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   573 AA;  66296 MW;  06F3E5CC4F79D1D8 CRC64;
     MTPESRDTTD LSPRGTQEME GIVVVKVEEE DEEDHFQKQR NKVESSPQVL SRSTTMNERA
     LLSSYLVAYR VAKEKMAHTA AEKIILPACM DMVRTIFDDK SADKLRTIPL SDNTISRRIC
     TIAKHLEAML ITRLQSGIDF AIQLDESTDI ASCPTLLVYV RYVWQDDFVE DLLCCLNLNS
     HITGLDLFTE LENCIVGQYK LNWKHCKGIS SDGAANMTGK HSRLTEKLLE ATHNNALWNH
     CFIHREALVS KEISPSLMDV LKKAVKIVNF IKGSSLNSRL LEILCSEIGV NHTHLLFHTE
     VRWLSQGKVL SRVYELRNEI YIFLIEKQSH LANIFENDIW VTKLAYLSDI FGILNELNLK
     IQGKNNDIFQ YLEHILGFQK TLLFWQARLK SNRPSYYMFP TLLQHIEENI INEDCLKEIK
     LEILLHLTSL SQTFNYYFPE EKFESLKENI WMKDPFAFQN PASIIKLNLE PEEENELLQL
     SSSFTLKNYY KTLSLSAFWI KIKDEFPLLS RKSISLLLPF TTTYLCELGF SILTRLKTKK
     RNRLNSAPDM RVALSSCVPD WKELMNRQAH PSH