F209A_HUMAN
ID F209A_HUMAN Reviewed; 171 AA.
AC Q5JX71; Q05C43;
DT 12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT 15-FEB-2005, sequence version 1.
DT 03-AUG-2022, entry version 110.
DE RecName: Full=Protein FAM209A;
DE Flags: Precursor;
GN Name=FAM209A {ECO:0000312|HGNC:HGNC:16100}; Synonyms=C20orf106;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=11780052; DOI=10.1038/414865a;
RA Deloukas P., Matthews L.H., Ashurst J.L., Burton J., Gilbert J.G.R.,
RA Jones M., Stavrides G., Almeida J.P., Babbage A.K., Bagguley C.L.,
RA Bailey J., Barlow K.F., Bates K.N., Beard L.M., Beare D.M., Beasley O.P.,
RA Bird C.P., Blakey S.E., Bridgeman A.M., Brown A.J., Buck D., Burrill W.D.,
RA Butler A.P., Carder C., Carter N.P., Chapman J.C., Clamp M., Clark G.,
RA Clark L.N., Clark S.Y., Clee C.M., Clegg S., Cobley V.E., Collier R.E.,
RA Connor R.E., Corby N.R., Coulson A., Coville G.J., Deadman R., Dhami P.D.,
RA Dunn M., Ellington A.G., Frankland J.A., Fraser A., French L., Garner P.,
RA Grafham D.V., Griffiths C., Griffiths M.N.D., Gwilliam R., Hall R.E.,
RA Hammond S., Harley J.L., Heath P.D., Ho S., Holden J.L., Howden P.J.,
RA Huckle E., Hunt A.R., Hunt S.E., Jekosch K., Johnson C.M., Johnson D.,
RA Kay M.P., Kimberley A.M., King A., Knights A., Laird G.K., Lawlor S.,
RA Lehvaeslaiho M.H., Leversha M.A., Lloyd C., Lloyd D.M., Lovell J.D.,
RA Marsh V.L., Martin S.L., McConnachie L.J., McLay K., McMurray A.A.,
RA Milne S.A., Mistry D., Moore M.J.F., Mullikin J.C., Nickerson T.,
RA Oliver K., Parker A., Patel R., Pearce T.A.V., Peck A.I.,
RA Phillimore B.J.C.T., Prathalingam S.R., Plumb R.W., Ramsay H., Rice C.M.,
RA Ross M.T., Scott C.E., Sehra H.K., Shownkeen R., Sims S., Skuce C.D.,
RA Smith M.L., Soderlund C., Steward C.A., Sulston J.E., Swann R.M.,
RA Sycamore N., Taylor R., Tee L., Thomas D.W., Thorpe A., Tracey A.,
RA Tromans A.C., Vaudin M., Wall M., Wallis J.M., Whitehead S.L.,
RA Whittaker P., Willey D.L., Williams L., Williams S.A., Wilming L.,
RA Wray P.W., Hubbard T., Durbin R.M., Bentley D.R., Beck S., Rogers J.;
RT "The DNA sequence and comparative analysis of human chromosome 20.";
RL Nature 414:865-871(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Testis;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- FUNCTION: May play a role in sperm acrosome biogenesis.
CC {ECO:0000250|UniProtKB:A2APA5}.
CC -!- INTERACTION:
CC Q5JX71; Q9UHX3: ADGRE2; NbExp=3; IntAct=EBI-18304435, EBI-11277970;
CC Q5JX71; Q15848: ADIPOQ; NbExp=3; IntAct=EBI-18304435, EBI-10827839;
CC Q5JX71; Q6RW13-2: AGTRAP; NbExp=3; IntAct=EBI-18304435, EBI-11522760;
CC Q5JX71; Q9NVV5-2: AIG1; NbExp=3; IntAct=EBI-18304435, EBI-11957045;
CC Q5JX71; Q9BVK2: ALG8; NbExp=3; IntAct=EBI-18304435, EBI-3921603;
CC Q5JX71; Q86W74-2: ANKRD46; NbExp=3; IntAct=EBI-18304435, EBI-12109402;
CC Q5JX71; Q9HDC9: APMAP; NbExp=3; IntAct=EBI-18304435, EBI-723950;
CC Q5JX71; P02656: APOC3; NbExp=3; IntAct=EBI-18304435, EBI-1220113;
CC Q5JX71; P05090: APOD; NbExp=3; IntAct=EBI-18304435, EBI-715495;
CC Q5JX71; Q9BQE5: APOL2; NbExp=3; IntAct=EBI-18304435, EBI-4290634;
CC Q5JX71; P29972: AQP1; NbExp=3; IntAct=EBI-18304435, EBI-745213;
CC Q5JX71; P41181: AQP2; NbExp=3; IntAct=EBI-18304435, EBI-12701138;
CC Q5JX71; Q92482: AQP3; NbExp=3; IntAct=EBI-18304435, EBI-2808854;
CC Q5JX71; Q9H2C2: ARV1; NbExp=3; IntAct=EBI-18304435, EBI-11724186;
CC Q5JX71; P07306: ASGR1; NbExp=3; IntAct=EBI-18304435, EBI-1172335;
CC Q5JX71; Q9HD20-3: ATP13A1; NbExp=3; IntAct=EBI-18304435, EBI-12069500;
CC Q5JX71; Q8NHY0: B4GALNT2; NbExp=3; IntAct=EBI-18304435, EBI-1042940;
CC Q5JX71; P23560-2: BDNF; NbExp=3; IntAct=EBI-18304435, EBI-12275524;
CC Q5JX71; O15155: BET1; NbExp=3; IntAct=EBI-18304435, EBI-749204;
CC Q5JX71; Q13323: BIK; NbExp=3; IntAct=EBI-18304435, EBI-700794;
CC Q5JX71; O95393: BMP10; NbExp=3; IntAct=EBI-18304435, EBI-3922513;
CC Q5JX71; Q12982: BNIP2; NbExp=3; IntAct=EBI-18304435, EBI-752094;
CC Q5JX71; Q12983: BNIP3; NbExp=3; IntAct=EBI-18304435, EBI-749464;
CC Q5JX71; Q8WVV5: BTN2A2; NbExp=3; IntAct=EBI-18304435, EBI-8648738;
CC Q5JX71; Q96F05: C11orf24; NbExp=3; IntAct=EBI-18304435, EBI-2836238;
CC Q5JX71; P06681: C2; NbExp=3; IntAct=EBI-18304435, EBI-2835920;
CC Q5JX71; Q8WVX3-2: C4orf3; NbExp=3; IntAct=EBI-18304435, EBI-12003442;
CC Q5JX71; Q8WVQ1: CANT1; NbExp=3; IntAct=EBI-18304435, EBI-16770554;
CC Q5JX71; Q8NHW4: CCL4L2; NbExp=3; IntAct=EBI-18304435, EBI-10271156;
CC Q5JX71; P19397: CD53; NbExp=3; IntAct=EBI-18304435, EBI-6657396;
CC Q5JX71; P13987: CD59; NbExp=3; IntAct=EBI-18304435, EBI-297972;
CC Q5JX71; P60033: CD81; NbExp=3; IntAct=EBI-18304435, EBI-712921;
CC Q5JX71; O14735: CDIPT; NbExp=3; IntAct=EBI-18304435, EBI-358858;
CC Q5JX71; Q92903: CDS1; NbExp=3; IntAct=EBI-18304435, EBI-13295305;
CC Q5JX71; O95674: CDS2; NbExp=3; IntAct=EBI-18304435, EBI-3913685;
CC Q5JX71; Q8N6F1-2: CLDN19; NbExp=3; IntAct=EBI-18304435, EBI-12256978;
CC Q5JX71; P57739: CLDN2; NbExp=3; IntAct=EBI-18304435, EBI-751440;
CC Q5JX71; O14493: CLDN4; NbExp=3; IntAct=EBI-18304435, EBI-9316372;
CC Q5JX71; Q8NHS1: CLDND2; NbExp=3; IntAct=EBI-18304435, EBI-11959453;
CC Q5JX71; Q6UXB4: CLEC4G; NbExp=3; IntAct=EBI-18304435, EBI-2114729;
CC Q5JX71; Q9NWW5: CLN6; NbExp=3; IntAct=EBI-18304435, EBI-6165897;
CC Q5JX71; Q96FZ5: CMTM7; NbExp=3; IntAct=EBI-18304435, EBI-2807956;
CC Q5JX71; O95406: CNIH1; NbExp=3; IntAct=EBI-18304435, EBI-12172273;
CC Q5JX71; Q9BT09: CNPY3; NbExp=3; IntAct=EBI-18304435, EBI-2835965;
CC Q5JX71; P29400-2: COL4A5; NbExp=3; IntAct=EBI-18304435, EBI-12211159;
CC Q5JX71; Q4VAQ0: COL8A2; NbExp=3; IntAct=EBI-18304435, EBI-10241815;
CC Q5JX71; P21964: COMT; NbExp=3; IntAct=EBI-18304435, EBI-372265;
CC Q5JX71; P40313: CTRL; NbExp=3; IntAct=EBI-18304435, EBI-7883667;
CC Q5JX71; Q4LDR2: CTXN3; NbExp=3; IntAct=EBI-18304435, EBI-12019274;
CC Q5JX71; O14569: CYB561D2; NbExp=3; IntAct=EBI-18304435, EBI-717654;
CC Q5JX71; O43169: CYB5B; NbExp=3; IntAct=EBI-18304435, EBI-1058710;
CC Q5JX71; Q9BQA9: CYBC1; NbExp=3; IntAct=EBI-18304435, EBI-2680384;
CC Q5JX71; Q5J5C9: DEFB121; NbExp=3; IntAct=EBI-18304435, EBI-10244198;
CC Q5JX71; Q7Z7B8: DEFB128; NbExp=3; IntAct=EBI-18304435, EBI-18310688;
CC Q5JX71; Q96LL9: DNAJC30; NbExp=3; IntAct=EBI-18304435, EBI-8639143;
CC Q5JX71; Q9UPQ8: DOLK; NbExp=3; IntAct=EBI-18304435, EBI-8645574;
CC Q5JX71; Q15125: EBP; NbExp=3; IntAct=EBI-18304435, EBI-3915253;
CC Q5JX71; Q9BV81: EMC6; NbExp=3; IntAct=EBI-18304435, EBI-2820492;
CC Q5JX71; P50402: EMD; NbExp=3; IntAct=EBI-18304435, EBI-489887;
CC Q5JX71; O75355-2: ENTPD3; NbExp=3; IntAct=EBI-18304435, EBI-12279764;
CC Q5JX71; Q5NDL2-3: EOGT; NbExp=3; IntAct=EBI-18304435, EBI-13052900;
CC Q5JX71; Q9UKR5: ERG28; NbExp=3; IntAct=EBI-18304435, EBI-711490;
CC Q5JX71; Q7Z2K6: ERMP1; NbExp=3; IntAct=EBI-18304435, EBI-10976398;
CC Q5JX71; Q7L5A8: FA2H; NbExp=3; IntAct=EBI-18304435, EBI-11337888;
CC Q5JX71; O75063: FAM20B; NbExp=3; IntAct=EBI-18304435, EBI-11090967;
CC Q5JX71; Q92520: FAM3C; NbExp=3; IntAct=EBI-18304435, EBI-2876774;
CC Q5JX71; Q969F0: FATE1; NbExp=3; IntAct=EBI-18304435, EBI-743099;
CC Q5JX71; P37268: FDFT1; NbExp=3; IntAct=EBI-18304435, EBI-714550;
CC Q5JX71; Q9Y3D6: FIS1; NbExp=3; IntAct=EBI-18304435, EBI-3385283;
CC Q5JX71; Q14802-3: FXYD3; NbExp=3; IntAct=EBI-18304435, EBI-12175685;
CC Q5JX71; P01350: GAST; NbExp=3; IntAct=EBI-18304435, EBI-3436637;
CC Q5JX71; O43681: GET3; NbExp=3; IntAct=EBI-18304435, EBI-2515857;
CC Q5JX71; Q9H3K2: GHITM; NbExp=3; IntAct=EBI-18304435, EBI-2868909;
CC Q5JX71; Q8WWP7: GIMAP1; NbExp=3; IntAct=EBI-18304435, EBI-11991950;
CC Q5JX71; P29033: GJB2; NbExp=3; IntAct=EBI-18304435, EBI-3905204;
CC Q5JX71; Q9NS71: GKN1; NbExp=3; IntAct=EBI-18304435, EBI-3933251;
CC Q5JX71; Q86XP6: GKN2; NbExp=3; IntAct=EBI-18304435, EBI-13380976;
CC Q5JX71; O14653: GOSR2; NbExp=3; IntAct=EBI-18304435, EBI-4401517;
CC Q5JX71; Q9NPR9: GPR108; NbExp=3; IntAct=EBI-18304435, EBI-11343451;
CC Q5JX71; Q8TDV0: GPR151; NbExp=3; IntAct=EBI-18304435, EBI-11955647;
CC Q5JX71; O60883: GPR37L1; NbExp=3; IntAct=EBI-18304435, EBI-2927498;
CC Q5JX71; P02724: GYPA; NbExp=3; IntAct=EBI-18304435, EBI-702665;
CC Q5JX71; Q6Y1H2: HACD2; NbExp=3; IntAct=EBI-18304435, EBI-530257;
CC Q5JX71; Q9HCP6: HHATL; NbExp=3; IntAct=EBI-18304435, EBI-5916693;
CC Q5JX71; P09601: HMOX1; NbExp=3; IntAct=EBI-18304435, EBI-2806151;
CC Q5JX71; P30519: HMOX2; NbExp=3; IntAct=EBI-18304435, EBI-712096;
CC Q5JX71; Q9BUP3-3: HTATIP2; NbExp=3; IntAct=EBI-18304435, EBI-12937691;
CC Q5JX71; P24593: IGFBP5; NbExp=3; IntAct=EBI-18304435, EBI-720480;
CC Q5JX71; Q9Y5U4: INSIG2; NbExp=3; IntAct=EBI-18304435, EBI-8503746;
CC Q5JX71; Q8N5M9: JAGN1; NbExp=3; IntAct=EBI-18304435, EBI-10266796;
CC Q5JX71; P43628: KIR2DL3; NbExp=3; IntAct=EBI-18304435, EBI-8632435;
CC Q5JX71; Q8TAF8: LHFPL5; NbExp=3; IntAct=EBI-18304435, EBI-2820517;
CC Q5JX71; Q9UBY5: LPAR3; NbExp=3; IntAct=EBI-18304435, EBI-12033434;
CC Q5JX71; Q7Z4F1: LRP10; NbExp=3; IntAct=EBI-18304435, EBI-2830349;
CC Q5JX71; P21145: MAL; NbExp=3; IntAct=EBI-18304435, EBI-3932027;
CC Q5JX71; Q9P0N8: MARCHF2; NbExp=3; IntAct=EBI-18304435, EBI-10317612;
CC Q5JX71; Q9GZY8-5: MFF; NbExp=3; IntAct=EBI-18304435, EBI-11956541;
CC Q5JX71; A0A0C4DFN3: MGLL; NbExp=3; IntAct=EBI-18304435, EBI-12866138;
CC Q5JX71; P30301: MIP; NbExp=3; IntAct=EBI-18304435, EBI-8449636;
CC Q5JX71; Q15546: MMD; NbExp=3; IntAct=EBI-18304435, EBI-17873222;
CC Q5JX71; Q8IY49-2: MMD2; NbExp=3; IntAct=EBI-18304435, EBI-13349813;
CC Q5JX71; P11836: MS4A1; NbExp=3; IntAct=EBI-18304435, EBI-2808234;
CC Q5JX71; Q5J8X5: MS4A13; NbExp=3; IntAct=EBI-18304435, EBI-12070086;
CC Q5JX71; Q96S97: MYADM; NbExp=3; IntAct=EBI-18304435, EBI-13301517;
CC Q5JX71; A6NDP7: MYADML2; NbExp=3; IntAct=EBI-18304435, EBI-17641390;
CC Q5JX71; Q9H115: NAPB; NbExp=3; IntAct=EBI-18304435, EBI-3921185;
CC Q5JX71; Q9UHE5: NAT8; NbExp=3; IntAct=EBI-18304435, EBI-2863634;
CC Q5JX71; O14931: NCR3; NbExp=3; IntAct=EBI-18304435, EBI-14989262;
CC Q5JX71; Q9NZG7: NINJ2; NbExp=3; IntAct=EBI-18304435, EBI-10317425;
CC Q5JX71; Q8N912: NRAC; NbExp=3; IntAct=EBI-18304435, EBI-12051377;
CC Q5JX71; Q8IXM6: NRM; NbExp=3; IntAct=EBI-18304435, EBI-10262547;
CC Q5JX71; Q969Y0: NXPE3; NbExp=3; IntAct=EBI-18304435, EBI-17973370;
CC Q5JX71; Q6UX06: OLFM4; NbExp=3; IntAct=EBI-18304435, EBI-2804156;
CC Q5JX71; Q8N138: ORMDL3; NbExp=3; IntAct=EBI-18304435, EBI-721750;
CC Q5JX71; Q9NRC9: OTOR; NbExp=3; IntAct=EBI-18304435, EBI-18311020;
CC Q5JX71; Q86WK9: PAQR7; NbExp=3; IntAct=EBI-18304435, EBI-10694587;
CC Q5JX71; I3L0A0: PEDS1-UBE2V1; NbExp=3; IntAct=EBI-18304435, EBI-12213001;
CC Q5JX71; Q9UHJ9-5: PGAP2; NbExp=3; IntAct=EBI-18304435, EBI-12092917;
CC Q5JX71; Q96LB9: PGLYRP3; NbExp=3; IntAct=EBI-18304435, EBI-12339509;
CC Q5JX71; P26678: PLN; NbExp=3; IntAct=EBI-18304435, EBI-692836;
CC Q5JX71; P60201-2: PLP1; NbExp=3; IntAct=EBI-18304435, EBI-12188331;
CC Q5JX71; Q04941: PLP2; NbExp=3; IntAct=EBI-18304435, EBI-608347;
CC Q5JX71; Q5VZY2: PLPP4; NbExp=3; IntAct=EBI-18304435, EBI-10485931;
CC Q5JX71; Q8IY26: PLPP6; NbExp=3; IntAct=EBI-18304435, EBI-11721828;
CC Q5JX71; Q01453: PMP22; NbExp=3; IntAct=EBI-18304435, EBI-2845982;
CC Q5JX71; P54315: PNLIPRP1; NbExp=3; IntAct=EBI-18304435, EBI-8652812;
CC Q5JX71; Q59EV6: PPGB; NbExp=3; IntAct=EBI-18304435, EBI-14210385;
CC Q5JX71; A5D903: PRB1; NbExp=3; IntAct=EBI-18304435, EBI-10173935;
CC Q5JX71; Q13635-3: PTCH1; NbExp=3; IntAct=EBI-18304435, EBI-14199621;
CC Q5JX71; Q02094: RHAG; NbExp=3; IntAct=EBI-18304435, EBI-14772355;
CC Q5JX71; Q9NS64: RPRM; NbExp=3; IntAct=EBI-18304435, EBI-1052363;
CC Q5JX71; Q5QGT7: RTP2; NbExp=3; IntAct=EBI-18304435, EBI-10244780;
CC Q5JX71; Q96GQ5: RUSF1; NbExp=3; IntAct=EBI-18304435, EBI-8636004;
CC Q5JX71; P29034: S100A2; NbExp=3; IntAct=EBI-18304435, EBI-752230;
CC Q5JX71; Q14162: SCARF1; NbExp=3; IntAct=EBI-18304435, EBI-12056025;
CC Q5JX71; O95968: SCGB1D1; NbExp=3; IntAct=EBI-18304435, EBI-12825395;
CC Q5JX71; O75711: SCRG1; NbExp=3; IntAct=EBI-18304435, EBI-10189029;
CC Q5JX71; Q96IW7: SEC22A; NbExp=3; IntAct=EBI-18304435, EBI-8652744;
CC Q5JX71; O75396: SEC22B; NbExp=3; IntAct=EBI-18304435, EBI-1058865;
CC Q5JX71; P60059: SEC61G; NbExp=3; IntAct=EBI-18304435, EBI-4402709;
CC Q5JX71; Q9Y6D0: SELENOK; NbExp=3; IntAct=EBI-18304435, EBI-9679163;
CC Q5JX71; Q1RMY5: SEMA6C; NbExp=3; IntAct=EBI-18304435, EBI-18310377;
CC Q5JX71; Q9Y6X1: SERP1; NbExp=3; IntAct=EBI-18304435, EBI-10329948;
CC Q5JX71; P11686: SFTPC; NbExp=3; IntAct=EBI-18304435, EBI-10197617;
CC Q5JX71; Q8WWT9: SLC13A3; NbExp=3; IntAct=EBI-18304435, EBI-12938720;
CC Q5JX71; P43005: SLC1A1; NbExp=3; IntAct=EBI-18304435, EBI-745376;
CC Q5JX71; Q8IWU4: SLC30A8; NbExp=3; IntAct=EBI-18304435, EBI-10262251;
CC Q5JX71; P78382: SLC35A1; NbExp=3; IntAct=EBI-18304435, EBI-12870360;
CC Q5JX71; Q96G79: SLC35A4; NbExp=3; IntAct=EBI-18304435, EBI-12363689;
CC Q5JX71; Q969S0: SLC35B4; NbExp=3; IntAct=EBI-18304435, EBI-10281213;
CC Q5JX71; Q7Z769: SLC35E3; NbExp=3; IntAct=EBI-18304435, EBI-13389236;
CC Q5JX71; Q8TBE7: SLC35G2; NbExp=3; IntAct=EBI-18304435, EBI-727304;
CC Q5JX71; Q9NVC3: SLC38A7; NbExp=3; IntAct=EBI-18304435, EBI-10314552;
CC Q5JX71; Q9HAB3: SLC52A2; NbExp=3; IntAct=EBI-18304435, EBI-10309896;
CC Q5JX71; Q8TBB6: SLC7A14; NbExp=3; IntAct=EBI-18304435, EBI-5235586;
CC Q5JX71; Q9NRQ5: SMCO4; NbExp=3; IntAct=EBI-18304435, EBI-8640191;
CC Q5JX71; B2RUZ4: SMIM1; NbExp=3; IntAct=EBI-18304435, EBI-12188413;
CC Q5JX71; Q6UX34: SNORC; NbExp=3; IntAct=EBI-18304435, EBI-11957067;
CC Q5JX71; P02808: STATH; NbExp=3; IntAct=EBI-18304435, EBI-738687;
CC Q5JX71; P61266: STX1B; NbExp=3; IntAct=EBI-18304435, EBI-9071709;
CC Q5JX71; Q13277: STX3; NbExp=3; IntAct=EBI-18304435, EBI-1394295;
CC Q5JX71; Q13190: STX5; NbExp=3; IntAct=EBI-18304435, EBI-714206;
CC Q5JX71; Q9UNK0: STX8; NbExp=3; IntAct=EBI-18304435, EBI-727240;
CC Q5JX71; O43759-2: SYNGR1; NbExp=3; IntAct=EBI-18304435, EBI-12187159;
CC Q5JX71; Q9BQS2-2: SYT15; NbExp=3; IntAct=EBI-18304435, EBI-13373352;
CC Q5JX71; Q9NZ01: TECR; NbExp=3; IntAct=EBI-18304435, EBI-2877718;
CC Q5JX71; Q9Y6I9: TEX264; NbExp=3; IntAct=EBI-18304435, EBI-10329860;
CC Q5JX71; P02786: TFRC; NbExp=3; IntAct=EBI-18304435, EBI-355727;
CC Q5JX71; P07204: THBD; NbExp=3; IntAct=EBI-18304435, EBI-941422;
CC Q5JX71; C9JKN6: THSD7B; NbExp=3; IntAct=EBI-18304435, EBI-17192156;
CC Q5JX71; Q9BZW4: TM6SF2; NbExp=3; IntAct=EBI-18304435, EBI-13082040;
CC Q5JX71; P55061: TMBIM6; NbExp=3; IntAct=EBI-18304435, EBI-1045825;
CC Q5JX71; Q9NV29: TMEM100; NbExp=3; IntAct=EBI-18304435, EBI-8644968;
CC Q5JX71; Q6UX40: TMEM107; NbExp=3; IntAct=EBI-18304435, EBI-12845616;
CC Q5JX71; P17152: TMEM11; NbExp=3; IntAct=EBI-18304435, EBI-723946;
CC Q5JX71; Q9BXJ8: TMEM120A; NbExp=3; IntAct=EBI-18304435, EBI-727322;
CC Q5JX71; Q5BJH2-2: TMEM128; NbExp=3; IntAct=EBI-18304435, EBI-10694905;
CC Q5JX71; Q9NV12: TMEM140; NbExp=3; IntAct=EBI-18304435, EBI-2844246;
CC Q5JX71; Q96I45: TMEM141; NbExp=3; IntAct=EBI-18304435, EBI-17681263;
CC Q5JX71; Q9NUH8: TMEM14B; NbExp=3; IntAct=EBI-18304435, EBI-8638294;
CC Q5JX71; Q9P0S9: TMEM14C; NbExp=3; IntAct=EBI-18304435, EBI-2339195;
CC Q5JX71; Q969S6: TMEM203; NbExp=3; IntAct=EBI-18304435, EBI-12274070;
CC Q5JX71; Q9BTX3: TMEM208; NbExp=3; IntAct=EBI-18304435, EBI-12876824;
CC Q5JX71; A2RU14: TMEM218; NbExp=3; IntAct=EBI-18304435, EBI-10173151;
CC Q5JX71; Q9H0R3: TMEM222; NbExp=3; IntAct=EBI-18304435, EBI-347385;
CC Q5JX71; Q8NBD8: TMEM229B; NbExp=3; IntAct=EBI-18304435, EBI-12195227;
CC Q5JX71; Q5W0B7: TMEM236; NbExp=3; IntAct=EBI-18304435, EBI-13378608;
CC Q5JX71; Q9BU79: TMEM243; NbExp=3; IntAct=EBI-18304435, EBI-12887458;
CC Q5JX71; Q8TBM7: TMEM254; NbExp=3; IntAct=EBI-18304435, EBI-11956809;
CC Q5JX71; Q69YG0: TMEM42; NbExp=3; IntAct=EBI-18304435, EBI-12038591;
CC Q5JX71; Q9BTV4: TMEM43; NbExp=3; IntAct=EBI-18304435, EBI-721293;
CC Q5JX71; Q9BQJ4: TMEM47; NbExp=3; IntAct=EBI-18304435, EBI-13370320;
CC Q5JX71; P56557: TMEM50B; NbExp=3; IntAct=EBI-18304435, EBI-12366453;
CC Q5JX71; Q9H2L4: TMEM60; NbExp=3; IntAct=EBI-18304435, EBI-2852148;
CC Q5JX71; Q6PI78: TMEM65; NbExp=3; IntAct=EBI-18304435, EBI-6656213;
CC Q5JX71; A0PK05: TMEM72; NbExp=3; IntAct=EBI-18304435, EBI-12878352;
CC Q5JX71; Q9BSE2: TMEM79; NbExp=3; IntAct=EBI-18304435, EBI-8649725;
CC Q5JX71; Q8N2M4: TMEM86A; NbExp=3; IntAct=EBI-18304435, EBI-12015604;
CC Q5JX71; Q8N661: TMEM86B; NbExp=3; IntAct=EBI-18304435, EBI-2548832;
CC Q5JX71; Q5BJF2: TMEM97; NbExp=3; IntAct=EBI-18304435, EBI-12111910;
CC Q5JX71; Q9NRS4: TMPRSS4; NbExp=3; IntAct=EBI-18304435, EBI-10313040;
CC Q5JX71; Q71RG4: TMUB2; NbExp=3; IntAct=EBI-18304435, EBI-2820477;
CC Q5JX71; P01375: TNF; NbExp=3; IntAct=EBI-18304435, EBI-359977;
CC Q5JX71; O14798: TNFRSF10C; NbExp=3; IntAct=EBI-18304435, EBI-717441;
CC Q5JX71; Q9H2S6-2: TNMD; NbExp=3; IntAct=EBI-18304435, EBI-12003398;
CC Q5JX71; Q9Y228: TRAF3IP3; NbExp=3; IntAct=EBI-18304435, EBI-765817;
CC Q5JX71; Q8N609: TRAM1L1; NbExp=3; IntAct=EBI-18304435, EBI-11996766;
CC Q5JX71; O60636: TSPAN2; NbExp=3; IntAct=EBI-18304435, EBI-3914288;
CC Q5JX71; Q86UF1: TSPAN33; NbExp=3; IntAct=EBI-18304435, EBI-12045841;
CC Q5JX71; P41732: TSPAN7; NbExp=3; IntAct=EBI-18304435, EBI-1042779;
CC Q5JX71; P30536: TSPO; NbExp=3; IntAct=EBI-18304435, EBI-6623146;
CC Q5JX71; Q5BVD1: TTMP; NbExp=3; IntAct=EBI-18304435, EBI-10243654;
CC Q5JX71; Q9GZX9: TWSG1; NbExp=3; IntAct=EBI-18304435, EBI-10304067;
CC Q5JX71; Q9Y385: UBE2J1; NbExp=3; IntAct=EBI-18304435, EBI-988826;
CC Q5JX71; Q9Y5Z9: UBIAD1; NbExp=3; IntAct=EBI-18304435, EBI-2819725;
CC Q5JX71; Q53HI1: UNC50; NbExp=3; IntAct=EBI-18304435, EBI-7601760;
CC Q5JX71; O75841: UPK1B; NbExp=3; IntAct=EBI-18304435, EBI-12237619;
CC Q5JX71; Q15836: VAMP3; NbExp=3; IntAct=EBI-18304435, EBI-722343;
CC Q5JX71; O75379: VAMP4; NbExp=3; IntAct=EBI-18304435, EBI-744953;
CC Q5JX71; O95183: VAMP5; NbExp=3; IntAct=EBI-18304435, EBI-10191195;
CC Q5JX71; Q9BQB6: VKORC1; NbExp=3; IntAct=EBI-18304435, EBI-6256462;
CC Q5JX71; Q96GC9: VMP1; NbExp=3; IntAct=EBI-18304435, EBI-2800296;
CC Q5JX71; Q14508: WFDC2; NbExp=3; IntAct=EBI-18304435, EBI-723529;
CC Q5JX71; O76024: WFS1; NbExp=3; IntAct=EBI-18304435, EBI-720609;
CC Q5JX71; Q96EC8: YIPF6; NbExp=3; IntAct=EBI-18304435, EBI-751210;
CC Q5JX71; O95159: ZFPL1; NbExp=3; IntAct=EBI-18304435, EBI-718439;
CC -!- SUBCELLULAR LOCATION: Nucleus inner membrane
CC {ECO:0000250|UniProtKB:A2APA5}; Single-pass type I membrane protein
CC {ECO:0000255}.
CC -!- MISCELLANEOUS: The primate lineage appears to have undergone gene
CC duplication of FAM209, such that humans contain FAM209A and FAM209B.
CC {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the FAM209 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAH29411.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence.; Evidence={ECO:0000305};
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DR EMBL; AL109806; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC029411; AAH29411.1; ALT_SEQ; mRNA.
DR EMBL; BC107704; AAI07705.1; -; mRNA.
DR CCDS; CCDS33493.1; -.
DR RefSeq; NP_001012989.2; NM_001012971.3.
DR AlphaFoldDB; Q5JX71; -.
DR BioGRID; 128313; 237.
DR IntAct; Q5JX71; 227.
DR STRING; 9606.ENSP00000360379; -.
DR PhosphoSitePlus; Q5JX71; -.
DR BioMuta; FAM209A; -.
DR DMDM; 74742707; -.
DR MassIVE; Q5JX71; -.
DR PaxDb; Q5JX71; -.
DR PeptideAtlas; Q5JX71; -.
DR PRIDE; Q5JX71; -.
DR ProteomicsDB; 63432; -.
DR Antibodypedia; 52593; 31 antibodies from 4 providers.
DR DNASU; 200232; -.
DR Ensembl; ENST00000371328.5; ENSP00000360379.4; ENSG00000124103.10.
DR GeneID; 200232; -.
DR KEGG; hsa:200232; -.
DR MANE-Select; ENST00000371328.5; ENSP00000360379.4; NM_001012971.4; NP_001012989.2.
DR UCSC; uc002xxx.4; human.
DR CTD; 200232; -.
DR GeneCards; FAM209A; -.
DR HGNC; HGNC:16100; FAM209A.
DR HPA; ENSG00000124103; Tissue enriched (testis).
DR neXtProt; NX_Q5JX71; -.
DR OpenTargets; ENSG00000124103; -.
DR PharmGKB; PA134974173; -.
DR VEuPathDB; HostDB:ENSG00000124103; -.
DR eggNOG; ENOG502SQY6; Eukaryota.
DR GeneTree; ENSGT00390000005057; -.
DR HOGENOM; CLU_1585866_0_0_1; -.
DR InParanoid; Q5JX71; -.
DR OMA; TICEIWG; -.
DR OrthoDB; 1258912at2759; -.
DR PhylomeDB; Q5JX71; -.
DR TreeFam; TF338191; -.
DR PathwayCommons; Q5JX71; -.
DR SignaLink; Q5JX71; -.
DR BioGRID-ORCS; 200232; 10 hits in 1011 CRISPR screens.
DR ChiTaRS; FAM209A; human.
DR GenomeRNAi; 200232; -.
DR Pharos; Q5JX71; Tdark.
DR PRO; PR:Q5JX71; -.
DR Proteomes; UP000005640; Chromosome 20.
DR RNAct; Q5JX71; protein.
DR Bgee; ENSG00000124103; Expressed in left testis and 86 other tissues.
DR GO; GO:0070062; C:extracellular exosome; HDA:UniProtKB.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005637; C:nuclear inner membrane; ISS:UniProtKB.
DR GO; GO:0005634; C:nucleus; HDA:UniProtKB.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
DR InterPro; IPR027943; FAM209.
DR PANTHER; PTHR35157; PTHR35157; 1.
DR Pfam; PF15206; FAM209; 1.
PE 1: Evidence at protein level;
KW Coiled coil; Differentiation; Membrane; Nucleus; Reference proteome;
KW Signal; Spermatogenesis; Transmembrane; Transmembrane helix.
FT SIGNAL 1..19
FT /evidence="ECO:0000255"
FT CHAIN 20..171
FT /note="Protein FAM209A"
FT /id="PRO_0000264155"
FT TOPO_DOM 20..52
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 53..73
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 74..171
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT REGION 81..107
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 114..139
FT /evidence="ECO:0000255"
FT VARIANT 66
FT /note="V -> A (in dbSNP:rs707554)"
FT /id="VAR_029621"
FT VARIANT 95
FT /note="L -> F (in dbSNP:rs1054343)"
FT /id="VAR_033761"
FT VARIANT 117
FT /note="M -> K (in dbSNP:rs1054349)"
FT /id="VAR_029622"
FT VARIANT 135
FT /note="R -> G (in dbSNP:rs1054358)"
FT /id="VAR_029623"
FT VARIANT 146
FT /note="R -> K (in dbSNP:rs1054361)"
FT /id="VAR_029624"
FT CONFLICT 98
FT /note="P -> L (in Ref. 2; AAH29411)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 171 AA; 19603 MW; 2CBB21C35AF9623A CRC64;
MWTLKSSLVL LLCLTCSYAF MFSSLRQKTS EPQGKVQYGE HFRIRQNLPE HTQGWLGSKW
LWLLFVVVPF VILQCQRDSE KNKEQSPPGL RGGQLHSPLK KKRNASPNKD CAFNTLMELE
VELMKFVSKV RNLKRAMATG SGSNLRLRKS EMPADPYHVT ICEIWGEESS S
