ID   F214A_CHICK             Reviewed;        1093 AA.
AC   Q5ZI58; F1NMC2;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   21-MAR-2012, sequence version 2.
DT   03-AUG-2022, entry version 73.
DE   RecName: Full=Protein FAM214A;
GN   Name=FAM214A; ORFNames=RCJMB04_30b20;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=CB; TISSUE=Bursa of Fabricius;
RX   PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA   Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA   Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA   Hayashizaki Y., Buerstedde J.-M.;
RT   "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT   function analysis.";
RL   Genome Biol. 6:R6.1-R6.9(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Red jungle fowl;
RX   PubMed=15592404; DOI=10.1038/nature03154;
RA   Hillier L.W., Miller W., Birney E., Warren W., Hardison R.C., Ponting C.P.,
RA   Bork P., Burt D.W., Groenen M.A.M., Delany M.E., Dodgson J.B.,
RA   Chinwalla A.T., Cliften P.F., Clifton S.W., Delehaunty K.D., Fronick C.,
RA   Fulton R.S., Graves T.A., Kremitzki C., Layman D., Magrini V.,
RA   McPherson J.D., Miner T.L., Minx P., Nash W.E., Nhan M.N., Nelson J.O.,
RA   Oddy L.G., Pohl C.S., Randall-Maher J., Smith S.M., Wallis J.W.,
RA   Yang S.-P., Romanov M.N., Rondelli C.M., Paton B., Smith J., Morrice D.,
RA   Daniels L., Tempest H.G., Robertson L., Masabanda J.S., Griffin D.K.,
RA   Vignal A., Fillon V., Jacobbson L., Kerje S., Andersson L.,
RA   Crooijmans R.P., Aerts J., van der Poel J.J., Ellegren H., Caldwell R.B.,
RA   Hubbard S.J., Grafham D.V., Kierzek A.M., McLaren S.R., Overton I.M.,
RA   Arakawa H., Beattie K.J., Bezzubov Y., Boardman P.E., Bonfield J.K.,
RA   Croning M.D.R., Davies R.M., Francis M.D., Humphray S.J., Scott C.E.,
RA   Taylor R.G., Tickle C., Brown W.R.A., Rogers J., Buerstedde J.-M.,
RA   Wilson S.A., Stubbs L., Ovcharenko I., Gordon L., Lucas S., Miller M.M.,
RA   Inoko H., Shiina T., Kaufman J., Salomonsen J., Skjoedt K., Wong G.K.-S.,
RA   Wang J., Liu B., Wang J., Yu J., Yang H., Nefedov M., Koriabine M.,
RA   Dejong P.J., Goodstadt L., Webber C., Dickens N.J., Letunic I., Suyama M.,
RA   Torrents D., von Mering C., Zdobnov E.M., Makova K., Nekrutenko A.,
RA   Elnitski L., Eswara P., King D.C., Yang S.-P., Tyekucheva S.,
RA   Radakrishnan A., Harris R.S., Chiaromonte F., Taylor J., He J.,
RA   Rijnkels M., Griffiths-Jones S., Ureta-Vidal A., Hoffman M.M., Severin J.,
RA   Searle S.M.J., Law A.S., Speed D., Waddington D., Cheng Z., Tuzun E.,
RA   Eichler E., Bao Z., Flicek P., Shteynberg D.D., Brent M.R., Bye J.M.,
RA   Huckle E.J., Chatterji S., Dewey C., Pachter L., Kouranov A.,
RA   Mourelatos Z., Hatzigeorgiou A.G., Paterson A.H., Ivarie R., Brandstrom M.,
RA   Axelsson E., Backstrom N., Berlin S., Webster M.T., Pourquie O.,
RA   Reymond A., Ucla C., Antonarakis S.E., Long M., Emerson J.J., Betran E.,
RA   Dupanloup I., Kaessmann H., Hinrichs A.S., Bejerano G., Furey T.S.,
RA   Harte R.A., Raney B., Siepel A., Kent W.J., Haussler D., Eyras E.,
RA   Castelo R., Abril J.F., Castellano S., Camara F., Parra G., Guigo R.,
RA   Bourque G., Tesler G., Pevzner P.A., Smit A., Fulton L.A., Mardis E.R.,
RA   Wilson R.K.;
RT   "Sequence and comparative analysis of the chicken genome provide unique
RT   perspectives on vertebrate evolution.";
RL   Nature 432:695-716(2004).
CC   -!- SIMILARITY: Belongs to the FAM214 family. {ECO:0000305}.
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DR   EMBL; AJ720926; CAG32585.1; -; mRNA.
DR   EMBL; AADN02045403; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AADN02045404; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AADN02045405; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AADN02045406; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AADN02045407; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AADN02045408; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AADN02045409; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AADN02045410; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; NP_001005811.1; NM_001005811.1.
DR   RefSeq; XP_015147386.1; XM_015291900.1.
DR   RefSeq; XP_015147387.1; XM_015291901.1.
DR   AlphaFoldDB; Q5ZI58; -.
DR   STRING; 9031.ENSGALP00000007252; -.
DR   PaxDb; Q5ZI58; -.
DR   Ensembl; ENSGALT00000080167; ENSGALP00000051257; ENSGALG00000042839.
DR   GeneID; 415416; -.
DR   KEGG; gga:415416; -.
DR   CTD; 56204; -.
DR   VEuPathDB; HostDB:geneid_415416; -.
DR   eggNOG; KOG2306; Eukaryota.
DR   GeneTree; ENSGT00940000157573; -.
DR   InParanoid; Q5ZI58; -.
DR   OrthoDB; 383904at2759; -.
DR   TreeFam; TF325496; -.
DR   PRO; PR:Q5ZI58; -.
DR   Proteomes; UP000000539; Chromosome 10.
DR   Bgee; ENSGALG00000042839; Expressed in cerebellum and 12 other tissues.
DR   ExpressionAtlas; Q5ZI58; baseline and differential.
DR   InterPro; IPR025261; DUF4210.
DR   InterPro; IPR033473; FAM214/SPAC3H8.04_C.
DR   Pfam; PF13889; Chromosome_seg; 1.
DR   Pfam; PF13915; DUF4210; 1.
DR   SMART; SM01177; DUF4210; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome.
FT   CHAIN           1..1093
FT                   /note="Protein FAM214A"
FT                   /id="PRO_0000315615"
FT   REGION          396..479
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          558..579
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          746..788
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        746..769
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        248
FT                   /note="R -> C (in Ref. 1; CAG32585)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        318
FT                   /note="I -> V (in Ref. 1; CAG32585)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   1093 AA;  122472 MW;  EBB9C74FB88A58B7 CRC64;
     MNAERNGSST DTLDEYFEYE AEEFLVSLAL LITEGRTPEH SIKGRTEGFH CPPAQSSQPP
     TTKHECSDKL AQCRQARRTR SEVMLLWKNN IPIMVEVMLL PDCCYSDEGP NTEGNDLNDP
     AIKQDALLLE RWILEPVPRQ SGDRFIEEKT LLLAVRSFVF FSQLSAWLSV SHGAVPRNIL
     YRVSAADVDL QWTFSQTPTE HVFPVPNVSH NVALKVSVQS LPRQSNYPVL TCSIHTNLSY
     YEKQMKERKL HQHSESSTAE LCGTSSPQRV CGKQAWTVIP EGLLNVKKTP EFTSSIRNLK
     LYPSTGLGSD FAASQSKIQC YNAAADSKTQ SHETAVRTFK SLSLVDSRVS NGHCSHQSTG
     ETNPLIGSLL QERQEVIARI AQHLIHCDPA TSPVVAGRPF NMRETSTPTP KAYRSTYEDE
     SLLRKGKETS PVPTVNLDNA IQEDGGEGKT RAIPEMPRLN PRAPVNHCGR PSAGEGNPLI
     DSLLQERRDV IARIAQHLIH CDPATSHVNG RPFKIHETSP VSSKIFRSTY EDENLLKKVK
     QPSSVSFAKS SFSLLEDSSK SKLKTPDTPI SPRLDGESKA SLKLQARRKL VLAKPSDAVQ
     NAFHQTSNKT SHSFTNTHTS SSCVKENKSE LLDKLEMMQS DYVQKDQITN RIKQCSNFSS
     VDEQICTNKL KERTVVSESN NTGTLNNLQI DKCRILEGTK KATVMQASDS LHKNELKCSD
     KDSKKPSIYE QNTQLISIEN YLNKDHDNFK NKNRQDKTKA AHDENEEPVG LDFQSTSQKK
     PTEDGSMRCE RLKNPDVQRA PSLKHTNTWR KHNFRSLDGT STKAFHPRTG LPLLSSPVPQ
     RKTHSGCFDL DSSLLQLKCL SARSPQQCIN RESDPESHGK PFLSSSAPPV TSLSLLGNFE
     ESVLNFRLDP LGIVEGFTAE VGASGVFCPT HMTLPVEVSF YSVSDDNAPS PYMGVITLES
     LGKRGYRVPP SGTIQVTLFN PNKTVVKMFV VIYDLREMPA NHQTFLRQRT FSVPVRREIK
     RTVNKENSQQ TEERLLRYLI HLRFQSSKSG KIYLHRDVRL LFSRKSMEVD SGAAYELKSY
     TESPTNPQFS PRC