F214B_HUMAN
ID F214B_HUMAN Reviewed; 538 AA.
AC Q7L5A3; B1AML4; B1AML5; D3DRN5; O60377; Q9BQ60; Q9HAI9; Q9P1Y9;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 140.
DE RecName: Full=Protein FAM214B;
GN Name=FAM214B; Synonyms=KIAA1539;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC TISSUE=Brain;
RX PubMed=10819331; DOI=10.1093/dnares/7.2.143;
RA Nagase T., Kikuno R., Ishikawa K., Hirosawa M., Ohara O.;
RT "Prediction of the coding sequences of unidentified human genes. XVII. The
RT complete sequences of 100 new cDNA clones from brain which code for large
RT proteins in vitro.";
RL DNA Res. 7:143-150(2000).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2 AND 3).
RC TISSUE=Embryo, and Teratocarcinoma;
RX PubMed=14702039; DOI=10.1038/ng1285;
RA Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
RA Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
RA Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
RA Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
RA Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H.,
RA Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M.,
RA Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K.,
RA Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T.,
RA Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M.,
RA Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S.,
RA Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H.,
RA Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K.,
RA Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N.,
RA Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
RA Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
RA Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
RA Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
RA Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y.,
RA Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K.,
RA Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T.,
RA Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T.,
RA Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y.,
RA Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H.,
RA Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y.,
RA Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H.,
RA Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O.,
RA Isogai T., Sugano S.;
RT "Complete sequencing and characterization of 21,243 full-length human
RT cDNAs.";
RL Nat. Genet. 36:40-45(2004).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC TISSUE=Amygdala;
RX PubMed=17974005; DOI=10.1186/1471-2164-8-399;
RA Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U.,
RA Wellenreuther R., Mehrle A., Schuster C., Bahr A., Bloecker H., Heubner D.,
RA Hoerlein A., Michel G., Wedler H., Koehrer K., Ottenwaelder B., Poustka A.,
RA Wiemann S., Schupp I.;
RT "The full-ORF clone resource of the German cDNA consortium.";
RL BMC Genomics 8:399-399(2007).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15164053; DOI=10.1038/nature02465;
RA Humphray S.J., Oliver K., Hunt A.R., Plumb R.W., Loveland J.E., Howe K.L.,
RA Andrews T.D., Searle S., Hunt S.E., Scott C.E., Jones M.C., Ainscough R.,
RA Almeida J.P., Ambrose K.D., Ashwell R.I.S., Babbage A.K., Babbage S.,
RA Bagguley C.L., Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K.,
RA Beasley H., Beasley O., Bird C.P., Bray-Allen S., Brown A.J., Brown J.Y.,
RA Burford D., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C.,
RA Chen Y., Clarke G., Clark S.Y., Clee C.M., Clegg S., Collier R.E.,
RA Corby N., Crosier M., Cummings A.T., Davies J., Dhami P., Dunn M.,
RA Dutta I., Dyer L.W., Earthrowl M.E., Faulkner L., Fleming C.J.,
RA Frankish A., Frankland J.A., French L., Fricker D.G., Garner P.,
RA Garnett J., Ghori J., Gilbert J.G.R., Glison C., Grafham D.V., Gribble S.,
RA Griffiths C., Griffiths-Jones S., Grocock R., Guy J., Hall R.E.,
RA Hammond S., Harley J.L., Harrison E.S.I., Hart E.A., Heath P.D.,
RA Henderson C.D., Hopkins B.L., Howard P.J., Howden P.J., Huckle E.,
RA Johnson C., Johnson D., Joy A.A., Kay M., Keenan S., Kershaw J.K.,
RA Kimberley A.M., King A., Knights A., Laird G.K., Langford C., Lawlor S.,
RA Leongamornlert D.A., Leversha M., Lloyd C., Lloyd D.M., Lovell J.,
RA Martin S., Mashreghi-Mohammadi M., Matthews L., McLaren S., McLay K.E.,
RA McMurray A., Milne S., Nickerson T., Nisbett J., Nordsiek G., Pearce A.V.,
RA Peck A.I., Porter K.M., Pandian R., Pelan S., Phillimore B., Povey S.,
RA Ramsey Y., Rand V., Scharfe M., Sehra H.K., Shownkeen R., Sims S.K.,
RA Skuce C.D., Smith M., Steward C.A., Swarbreck D., Sycamore N., Tester J.,
RA Thorpe A., Tracey A., Tromans A., Thomas D.W., Wall M., Wallis J.M.,
RA West A.P., Whitehead S.L., Willey D.L., Williams S.A., Wilming L.,
RA Wray P.W., Young L., Ashurst J.L., Coulson A., Blocker H., Durbin R.M.,
RA Sulston J.E., Hubbard T., Jackson M.J., Bentley D.R., Beck S., Rogers J.,
RA Dunham I.;
RT "DNA sequence and analysis of human chromosome 9.";
RL Nature 429:369-374(2004).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M.,
RA Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J.,
RA Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S.,
RA Turner R., Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H.,
RA Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K.,
RA Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D.,
RA Hunkapiller M.W., Myers E.W., Venter J.C.;
RL Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC TISSUE=Placenta;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [7]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 299-538 (ISOFORM 1).
RA Lamerdin J.E., McCready P.M., Skowronski E., Adamson A.W.,
RA Burkhart-Schultz K., Gordon L., Kyle A., Ramirez M., Stilwagen S., Phan H.,
RA Velasco N., Garnes J., Danganan L., Poundstone P., Christensen M.,
RA Georgescu A., Avila J., Liu S., Attix C., Andreise T., Trankheim M.,
RA Amico-Keller G., Coefield J., Duarte S., Lucas S., Bruce R., Thomas P.,
RA Quan G., Kronmiller B., Arellano A., Montgomery M., Ow D., Nolan M.,
RA Trong S., Kobayashi A., Olsen A.O., Carrano A.V.;
RT "Sequence analysis of a human P1 clone containing the XRCC9 DNA repair
RT gene.";
RL Submitted (MAR-1998) to the EMBL/GenBank/DDBJ databases.
CC -!- INTERACTION:
CC Q7L5A3; Q9NYB9-2: ABI2; NbExp=3; IntAct=EBI-745689, EBI-11096309;
CC Q7L5A3; Q9ULX6: AKAP8L; NbExp=3; IntAct=EBI-745689, EBI-357530;
CC Q7L5A3; O95429: BAG4; NbExp=5; IntAct=EBI-745689, EBI-2949658;
CC Q7L5A3; Q6PI77: BHLHB9; NbExp=3; IntAct=EBI-745689, EBI-11519926;
CC Q7L5A3; Q13137: CALCOCO2; NbExp=3; IntAct=EBI-745689, EBI-739580;
CC Q7L5A3; Q86Z20: CCDC125; NbExp=3; IntAct=EBI-745689, EBI-11977221;
CC Q7L5A3; Q8NHQ1: CEP70; NbExp=5; IntAct=EBI-745689, EBI-739624;
CC Q7L5A3; A8MQ03: CYSRT1; NbExp=3; IntAct=EBI-745689, EBI-3867333;
CC Q7L5A3; Q14689: DIP2A; NbExp=3; IntAct=EBI-745689, EBI-2564275;
CC Q7L5A3; Q96EY1-2: DNAJA3; NbExp=3; IntAct=EBI-745689, EBI-3952284;
CC Q7L5A3; Q5JST6: EFHC2; NbExp=3; IntAct=EBI-745689, EBI-2349927;
CC Q7L5A3; O00167-2: EYA2; NbExp=3; IntAct=EBI-745689, EBI-12807776;
CC Q7L5A3; Q14192: FHL2; NbExp=3; IntAct=EBI-745689, EBI-701903;
CC Q7L5A3; Q5TD97: FHL5; NbExp=5; IntAct=EBI-745689, EBI-750641;
CC Q7L5A3; Q08379: GOLGA2; NbExp=3; IntAct=EBI-745689, EBI-618309;
CC Q7L5A3; O75031: HSF2BP; NbExp=3; IntAct=EBI-745689, EBI-7116203;
CC Q7L5A3; Q9UJY1: HSPB8; NbExp=3; IntAct=EBI-745689, EBI-739074;
CC Q7L5A3; Q13422: IKZF1; NbExp=6; IntAct=EBI-745689, EBI-745305;
CC Q7L5A3; Q13422-7: IKZF1; NbExp=3; IntAct=EBI-745689, EBI-11522367;
CC Q7L5A3; O95235: KIF20A; NbExp=4; IntAct=EBI-745689, EBI-2551319;
CC Q7L5A3; O00505: KPNA3; NbExp=3; IntAct=EBI-745689, EBI-358297;
CC Q7L5A3; O76011: KRT34; NbExp=3; IntAct=EBI-745689, EBI-1047093;
CC Q7L5A3; Q3LI72: KRTAP19-5; NbExp=3; IntAct=EBI-745689, EBI-1048945;
CC Q7L5A3; Q3LI70: KRTAP19-6; NbExp=3; IntAct=EBI-745689, EBI-12805508;
CC Q7L5A3; Q3LI66: KRTAP6-2; NbExp=3; IntAct=EBI-745689, EBI-11962084;
CC Q7L5A3; P25791-3: LMO2; NbExp=3; IntAct=EBI-745689, EBI-11959475;
CC Q7L5A3; Q9BRK4: LZTS2; NbExp=3; IntAct=EBI-745689, EBI-741037;
CC Q7L5A3; Q99750: MDFI; NbExp=4; IntAct=EBI-745689, EBI-724076;
CC Q7L5A3; Q8NCR3: MFI; NbExp=3; IntAct=EBI-745689, EBI-744790;
CC Q7L5A3; Q9UJV3-2: MID2; NbExp=3; IntAct=EBI-745689, EBI-10172526;
CC Q7L5A3; Q13064: MKRN3; NbExp=3; IntAct=EBI-745689, EBI-2340269;
CC Q7L5A3; O00160: MYO1F; NbExp=3; IntAct=EBI-745689, EBI-741792;
CC Q7L5A3; Q9ULV0-2: MYO5B; NbExp=3; IntAct=EBI-745689, EBI-14093244;
CC Q7L5A3; Q8TDC0: MYOZ3; NbExp=3; IntAct=EBI-745689, EBI-5662487;
CC Q7L5A3; Q9NR12: PDLIM7; NbExp=3; IntAct=EBI-745689, EBI-350517;
CC Q7L5A3; Q99471: PFDN5; NbExp=3; IntAct=EBI-745689, EBI-357275;
CC Q7L5A3; Q9NRD5: PICK1; NbExp=3; IntAct=EBI-745689, EBI-79165;
CC Q7L5A3; Q9NQX0: PRDM6; NbExp=3; IntAct=EBI-745689, EBI-11320284;
CC Q7L5A3; Q16825: PTPN21; NbExp=3; IntAct=EBI-745689, EBI-2860264;
CC Q7L5A3; P57052: RBM11; NbExp=3; IntAct=EBI-745689, EBI-741332;
CC Q7L5A3; Q9UHJ3: SFMBT1; NbExp=3; IntAct=EBI-745689, EBI-747398;
CC Q7L5A3; Q8ND83: SLAIN1; NbExp=3; IntAct=EBI-745689, EBI-10269374;
CC Q7L5A3; O60504: SORBS3; NbExp=3; IntAct=EBI-745689, EBI-741237;
CC Q7L5A3; Q9NUY8: TBC1D23; NbExp=3; IntAct=EBI-745689, EBI-2853126;
CC Q7L5A3; Q96N21: TEPSIN; NbExp=3; IntAct=EBI-745689, EBI-11139477;
CC Q7L5A3; Q08117-2: TLE5; NbExp=3; IntAct=EBI-745689, EBI-11741437;
CC Q7L5A3; Q12933: TRAF2; NbExp=3; IntAct=EBI-745689, EBI-355744;
CC Q7L5A3; Q9BUZ4: TRAF4; NbExp=5; IntAct=EBI-745689, EBI-3650647;
CC Q7L5A3; P14373: TRIM27; NbExp=7; IntAct=EBI-745689, EBI-719493;
CC Q7L5A3; Q9Y2B5: VPS9D1; NbExp=3; IntAct=EBI-745689, EBI-9031083;
CC Q7L5A3; Q9NZC7-5: WWOX; NbExp=3; IntAct=EBI-745689, EBI-12040603;
CC Q7L5A3; O00308: WWP2; NbExp=3; IntAct=EBI-745689, EBI-743923;
CC Q7L5A3; Q9H0C1: ZMYND12; NbExp=3; IntAct=EBI-745689, EBI-12030590;
CC Q7L5A3; Q9P2Y4: ZNF219; NbExp=3; IntAct=EBI-745689, EBI-3937106;
CC Q7L5A3; Q7Z3I7: ZNF572; NbExp=3; IntAct=EBI-745689, EBI-10172590;
CC Q7L5A3; Q8N720: ZNF655; NbExp=3; IntAct=EBI-745689, EBI-625509;
CC Q7L5A3; Q9UGI0: ZRANB1; NbExp=3; IntAct=EBI-745689, EBI-527853;
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=3;
CC Name=1;
CC IsoId=Q7L5A3-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q7L5A3-2; Sequence=VSP_030063;
CC Name=3;
CC IsoId=Q7L5A3-3; Sequence=VSP_042437;
CC -!- SIMILARITY: Belongs to the FAM214 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAC07982.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=BAA96063.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR EMBL; AB040972; BAA96063.1; ALT_INIT; mRNA.
DR EMBL; AK021622; BAB13857.1; -; mRNA.
DR EMBL; AK022837; BAG51123.1; -; mRNA.
DR EMBL; AL583909; CAC29493.1; -; mRNA.
DR EMBL; AC004472; AAC07982.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AL353795; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CH471071; EAW58387.1; -; Genomic_DNA.
DR EMBL; CH471071; EAW58388.1; -; Genomic_DNA.
DR EMBL; CH471071; EAW58389.1; -; Genomic_DNA.
DR EMBL; CH471071; EAW58391.1; -; Genomic_DNA.
DR EMBL; CH471071; EAW58392.1; -; Genomic_DNA.
DR EMBL; BC004406; AAH04406.1; -; mRNA.
DR CCDS; CCDS6578.1; -. [Q7L5A3-1]
DR PIR; T02247; T02247.
DR RefSeq; NP_001304920.1; NM_001317991.1. [Q7L5A3-1]
DR RefSeq; NP_079458.2; NM_025182.3. [Q7L5A3-1]
DR RefSeq; XP_005251645.1; XM_005251588.1. [Q7L5A3-1]
DR RefSeq; XP_005251647.1; XM_005251590.1. [Q7L5A3-1]
DR RefSeq; XP_005251648.1; XM_005251591.1. [Q7L5A3-1]
DR RefSeq; XP_011516339.1; XM_011518037.1. [Q7L5A3-1]
DR RefSeq; XP_011516345.1; XM_011518043.1.
DR RefSeq; XP_011516346.1; XM_011518044.1.
DR RefSeq; XP_016870659.1; XM_017015170.1.
DR AlphaFoldDB; Q7L5A3; -.
DR BioGRID; 123202; 67.
DR IntAct; Q7L5A3; 59.
DR MINT; Q7L5A3; -.
DR STRING; 9606.ENSP00000367823; -.
DR iPTMnet; Q7L5A3; -.
DR PhosphoSitePlus; Q7L5A3; -.
DR BioMuta; FAM214B; -.
DR DMDM; 74749892; -.
DR jPOST; Q7L5A3; -.
DR MassIVE; Q7L5A3; -.
DR PaxDb; Q7L5A3; -.
DR PeptideAtlas; Q7L5A3; -.
DR PRIDE; Q7L5A3; -.
DR ProteomicsDB; 68803; -. [Q7L5A3-1]
DR ProteomicsDB; 68804; -. [Q7L5A3-2]
DR ProteomicsDB; 68805; -. [Q7L5A3-3]
DR Antibodypedia; 56170; 23 antibodies from 9 providers.
DR DNASU; 80256; -.
DR Ensembl; ENST00000322813.10; ENSP00000319897.5; ENSG00000005238.20. [Q7L5A3-1]
DR Ensembl; ENST00000378557.1; ENSP00000367819.1; ENSG00000005238.20. [Q7L5A3-1]
DR Ensembl; ENST00000378561.5; ENSP00000367823.1; ENSG00000005238.20. [Q7L5A3-1]
DR Ensembl; ENST00000378566.5; ENSP00000367829.1; ENSG00000005238.20. [Q7L5A3-3]
DR Ensembl; ENST00000488109.6; ENSP00000475120.1; ENSG00000005238.20. [Q7L5A3-1]
DR Ensembl; ENST00000603301.5; ENSP00000474335.1; ENSG00000005238.20. [Q7L5A3-1]
DR Ensembl; ENST00000605244.5; ENSP00000474833.1; ENSG00000005238.20. [Q7L5A3-1]
DR GeneID; 80256; -.
DR KEGG; hsa:80256; -.
DR MANE-Select; ENST00000322813.10; ENSP00000319897.5; NM_025182.4; NP_079458.2.
DR UCSC; uc003zwl.4; human. [Q7L5A3-1]
DR CTD; 80256; -.
DR DisGeNET; 80256; -.
DR GeneCards; FAM214B; -.
DR HGNC; HGNC:25666; FAM214B.
DR HPA; ENSG00000005238; Low tissue specificity.
DR neXtProt; NX_Q7L5A3; -.
DR OpenTargets; ENSG00000005238; -.
DR PharmGKB; PA134880815; -.
DR VEuPathDB; HostDB:ENSG00000005238; -.
DR eggNOG; KOG2306; Eukaryota.
DR GeneTree; ENSGT00940000159834; -.
DR HOGENOM; CLU_080879_0_0_1; -.
DR InParanoid; Q7L5A3; -.
DR OMA; CVVEQRG; -.
DR OrthoDB; 383904at2759; -.
DR PhylomeDB; Q7L5A3; -.
DR TreeFam; TF325496; -.
DR PathwayCommons; Q7L5A3; -.
DR SignaLink; Q7L5A3; -.
DR BioGRID-ORCS; 80256; 12 hits in 1078 CRISPR screens.
DR ChiTaRS; FAM214B; human.
DR GeneWiki; KIAA1539; -.
DR GenomeRNAi; 80256; -.
DR Pharos; Q7L5A3; Tdark.
DR PRO; PR:Q7L5A3; -.
DR Proteomes; UP000005640; Chromosome 9.
DR RNAct; Q7L5A3; protein.
DR Bgee; ENSG00000005238; Expressed in granulocyte and 203 other tissues.
DR Genevisible; Q7L5A3; HS.
DR GO; GO:0005634; C:nucleus; IDA:LIFEdb.
DR InterPro; IPR025261; DUF4210.
DR InterPro; IPR033473; FAM214/SPAC3H8.04_C.
DR Pfam; PF13889; Chromosome_seg; 1.
DR Pfam; PF13915; DUF4210; 1.
DR SMART; SM01177; DUF4210; 1.
PE 1: Evidence at protein level;
KW Alternative splicing; Phosphoprotein; Reference proteome.
FT CHAIN 1..538
FT /note="Protein FAM214B"
FT /id="PRO_0000313620"
FT REGION 1..114
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 133..300
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 133..158
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 227..241
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 254
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q8BR27"
FT MOD_RES 255
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q8BR27"
FT VAR_SEQ 1..305
FT /note="Missing (in isoform 3)"
FT /evidence="ECO:0000303|PubMed:14702039"
FT /id="VSP_042437"
FT VAR_SEQ 435..538
FT /note="NQTVVKMFLVTFDFSDMPAAHMTFLRHRLFLVPVGEEGNANPTHRLLCYLLH
FT LRFRSSRSGRLSLHGDIRLLFSRRSLELDTGLPYELQAVTEAPHNPRYSPLP -> NPF
FT TSPTL (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:14702039"
FT /id="VSP_030063"
FT CONFLICT Q7L5A3-2:435
FT /note="N -> S (in Ref. 2; BAB13857)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 538 AA; 56690 MW; 7BF7E9EB38167BDC CRC64;
MRHVQAEPSP SSEPEAGPSQ PPVRQGALQG GLLMGYSPAG GATSPGVYQV SIFSPPAGTS
EPHRALKRQA PSTEGPRELK RGPGLGAREG LPPEEPSTVG LLGPEGPGLG LGVASQHFSH
RGLCVVEQRS SVTSSWTSGA WSPPCPPSNA SCNTLHTRDW ASPDPGGQGS LGESPGPAPP
GQLHTLDTDL HSLAQIGGKS PVAGVGNGGS LWPRESPGTA NGHSPEHTPP GPGPPGPCPT
KRRLLPAGEA PDVSSEEEGP APRRRRGSLG HPTAANSSDA KATPFWSHLL PGPKEPVLDP
TDCGPMGRRL KGARRLKLSP LRSLRKGPGL LSPPSASPVP TPAVSRTLLG NFEESLLRGR
FAPSGHIEGF TAEIGASGSY CPQHVTLPVT VTFFDVSEQN APAPFLGIVD LNPLGRKGYS
VPKVGTVQVT LFNPNQTVVK MFLVTFDFSD MPAAHMTFLR HRLFLVPVGE EGNANPTHRL
LCYLLHLRFR SSRSGRLSLH GDIRLLFSRR SLELDTGLPY ELQAVTEAPH NPRYSPLP
