F215A_HUMAN
ID F215A_HUMAN Reviewed; 114 AA.
AC Q9Y5M1; Q6NTD6;
DT 30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT 21-JUN-2005, sequence version 2.
DT 25-MAY-2022, entry version 100.
DE RecName: Full=Uncharacterized protein FAM215A;
DE AltName: Full=Apoptosis-related protein 2;
DE Short=APR-2;
GN Name=FAM215A; Synonyms=APR2, C17orf88;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=10948432; DOI=10.2144/00292st06;
RA Zhu F., Yan W., Zhao Z.L., Chai Y.B., Lu F., Wang Q., Peng W.D., Yang A.G.,
RA Wang C.J.;
RT "Improved PCR-based subtractive hybridization strategy for cloning
RT differentially expressed genes.";
RL BioTechniques 29:310-313(2000).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16625196; DOI=10.1038/nature04689;
RA Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R.,
RA Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A.,
RA Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J.,
RA Chang J.L., Chen C.-K., Cook A., Corum B., Cuomo C.A., de Jong P.J.,
RA DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R., Gnerre S.,
RA Goldstein S., Grafham D.V., Grocock R., Hafez N., Hagopian D.S., Hart E.,
RA Norman C.H., Humphray S., Jaffe D.B., Jones M., Kamal M., Khodiyar V.K.,
RA LaButti K., Laird G., Lehoczky J., Liu X., Lokyitsang T., Loveland J.,
RA Lui A., Macdonald P., Major J.E., Matthews L., Mauceli E., McCarroll S.A.,
RA Mihalev A.H., Mudge J., Nguyen C., Nicol R., O'Leary S.B., Osoegawa K.,
RA Schwartz D.C., Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D.,
RA Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A.,
RA Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C.;
RT "DNA sequence of human chromosome 17 and analysis of rearrangement in the
RT human lineage.";
RL Nature 440:1045-1049(2006).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- CAUTION: Product of a dubious CDS prediction. May be a non-coding RNA.
CC No experimental confirmation available. {ECO:0000305}.
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DR EMBL; AF143236; AAD31315.1; -; mRNA.
DR EMBL; AC007993; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC069097; -; NOT_ANNOTATED_CDS; mRNA.
DR AlphaFoldDB; Q9Y5M1; -.
DR STRING; 9606.ENSP00000464743; -.
DR BioMuta; HGNC:17505; -.
DR PaxDb; Q9Y5M1; -.
DR PRIDE; Q9Y5M1; -.
DR UCSC; uc010wiq.2; human.
DR GeneCards; FAM215A; -.
DR HGNC; HGNC:17505; FAM215A.
DR neXtProt; NX_Q9Y5M1; -.
DR eggNOG; ENOG502TF35; Eukaryota.
DR InParanoid; Q9Y5M1; -.
DR PathwayCommons; Q9Y5M1; -.
DR Pharos; Q9Y5M1; Tdark.
DR PRO; PR:Q9Y5M1; -.
DR Proteomes; UP000005640; Unplaced.
DR RNAct; Q9Y5M1; protein.
PE 5: Uncertain;
KW Reference proteome.
FT CHAIN 1..114
FT /note="Uncharacterized protein FAM215A"
FT /id="PRO_0000064641"
FT REGION 26..45
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 72..98
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 39
FT /note="T -> M (in Ref. 1; AAD31315)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 114 AA; 11973 MW; C13EE379355D88F8 CRC64;
MVSLWVEGTF PPPGFGLAHV ACSGHGMKQK RKPASSEPTP EDALGGSAVP VRFHLHPEGL
LWCSRCFFSH GPKGSEPPGR SAGLQGATER SGRPSVQAQA QACENLVPAT VWDG