F216A_MOUSE
ID F216A_MOUSE Reviewed; 251 AA.
AC Q9DB54; Q3UD74; Q6PFA4;
DT 29-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 107.
DE RecName: Full=Protein FAM216A;
GN Name=Fam216a;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Bone marrow, and Cerebellum;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=129, and FVB/N; TISSUE=Brain, and Mammary tumor;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- SIMILARITY: Belongs to the FAM216 family. {ECO:0000305}.
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DR EMBL; AK005211; BAB23885.1; -; mRNA.
DR EMBL; AK150218; BAE29387.1; -; mRNA.
DR EMBL; BC019498; AAH19498.1; -; mRNA.
DR EMBL; BC057658; AAH57658.1; -; mRNA.
DR EMBL; BC061033; AAH61033.1; -; mRNA.
DR CCDS; CCDS39257.1; -.
DR RefSeq; NP_081159.1; NM_026883.3.
DR AlphaFoldDB; Q9DB54; -.
DR IntAct; Q9DB54; 5.
DR STRING; 10090.ENSMUSP00000031419; -.
DR PhosphoSitePlus; Q9DB54; -.
DR PaxDb; Q9DB54; -.
DR PRIDE; Q9DB54; -.
DR ProteomicsDB; 271533; -.
DR Antibodypedia; 31011; 107 antibodies from 19 providers.
DR Ensembl; ENSMUST00000031419; ENSMUSP00000031419; ENSMUSG00000029463.
DR GeneID; 68948; -.
DR KEGG; mmu:68948; -.
DR UCSC; uc008zld.1; mouse.
DR CTD; 29902; -.
DR MGI; MGI:1916198; Fam216a.
DR VEuPathDB; HostDB:ENSMUSG00000029463; -.
DR eggNOG; ENOG502SC0D; Eukaryota.
DR GeneTree; ENSGT00940000154512; -.
DR HOGENOM; CLU_096833_0_0_1; -.
DR InParanoid; Q9DB54; -.
DR OMA; KPGRLFM; -.
DR OrthoDB; 1092818at2759; -.
DR PhylomeDB; Q9DB54; -.
DR TreeFam; TF337546; -.
DR BioGRID-ORCS; 68948; 4 hits in 70 CRISPR screens.
DR ChiTaRS; Fam216a; mouse.
DR PRO; PR:Q9DB54; -.
DR Proteomes; UP000000589; Chromosome 5.
DR RNAct; Q9DB54; protein.
DR Bgee; ENSMUSG00000029463; Expressed in spermatocyte and 251 other tissues.
DR Genevisible; Q9DB54; MM.
DR InterPro; IPR029373; FAM216.
DR PANTHER; PTHR16476; PTHR16476; 1.
DR Pfam; PF15107; FAM216B; 1.
PE 2: Evidence at transcript level;
KW Reference proteome.
FT CHAIN 1..251
FT /note="Protein FAM216A"
FT /id="PRO_0000288862"
FT REGION 1..41
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 103
FT /note="S -> P (in Ref. 2; AAH57658)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 251 AA; 28339 MW; E4A5A00AF6AF31B7 CRC64;
MPSRWPGVAG PPALARTEGG EGSAGHSYPQ NSKGTGEQHK ADRIKEGHRV YAHIAKLQEL
WKTTQIQTIH IPKSMTDASF LKHPELTLGQ KRYLCSVAKI CNSSYLRTLM KRQYMHIFHH
GSQKTGVLTH HRGHMSSRYS QKQHSPCTAW RHHLEREDSL SIAAGAPEMI IHSLWRPLRH
KEGLKIGYAS KTRCKSLKIF RRPGRLFLLP VPSNDSQSCP SEETQEEDLL NKCMQSMSIQ
EQGPAHASLT V