F217A_MOUSE
ID F217A_MOUSE Reviewed; 419 AA.
AC Q9D9W6;
DT 16-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 77.
DE RecName: Full=Protein FAM217A;
GN Name=Fam217a;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
CC -!- SIMILARITY: Belongs to the FAM217 family. {ECO:0000305}.
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DR EMBL; AK006388; BAB24562.1; -; mRNA.
DR RefSeq; NP_082243.1; NM_027967.1.
DR AlphaFoldDB; Q9D9W6; -.
DR iPTMnet; Q9D9W6; -.
DR PhosphoSitePlus; Q9D9W6; -.
DR PaxDb; Q9D9W6; -.
DR PRIDE; Q9D9W6; -.
DR ProteomicsDB; 271534; -.
DR Antibodypedia; 44131; 64 antibodies from 15 providers.
DR Ensembl; ENSMUST00000225242; ENSMUSP00000153128; ENSMUSG00000021414.
DR GeneID; 71864; -.
DR KEGG; mmu:71864; -.
DR UCSC; uc007qbr.1; mouse.
DR CTD; 222826; -.
DR MGI; MGI:1919114; Fam217a.
DR VEuPathDB; HostDB:ENSMUSG00000021414; -.
DR eggNOG; ENOG502SAD6; Eukaryota.
DR GeneTree; ENSGT00940000154543; -.
DR InParanoid; Q9D9W6; -.
DR OrthoDB; 529883at2759; -.
DR BioGRID-ORCS; 71864; 1 hit in 72 CRISPR screens.
DR PRO; PR:Q9D9W6; -.
DR Proteomes; UP000000589; Chromosome 13.
DR RNAct; Q9D9W6; protein.
DR Bgee; ENSMUSG00000021414; Expressed in spermatid and 44 other tissues.
DR ExpressionAtlas; Q9D9W6; baseline and differential.
DR InterPro; IPR029266; FAM217.
DR PANTHER; PTHR22145; PTHR22145; 2.
DR Pfam; PF15344; FAM217; 1.
PE 2: Evidence at transcript level;
KW Reference proteome.
FT CHAIN 1..419
FT /note="Protein FAM217A"
FT /id="PRO_0000089541"
FT REGION 1..60
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 96..119
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 236..299
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 317..382
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..27
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 28..42
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 102..119
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 274..299
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 317..345
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 419 AA; 46769 MW; 43DC7DC23C8A9434 CRC64;
MGRKSNESCS SSLHVSSISQ ENHSQWNLDA EELFDEKETF SSENDGAAGG KTNKSHLENP
AEQLILQLTV SEHAHSRSQQ NSSQGVFQLW SSPVNKGSTV DKRNSSVEEN VTDESDLSEN
EKMNDSLLSY FKKMDLNLKP ETIEHVERPF PEEAGQVPVY ADFLPAPFNT LDLHRFAFSK
CESWKAAVEP PESSIERLIL RLLELERLQH MTIQRERPRL QSTFYSSMFS MAERPSSSKA
IATKAKAPKI PETSTLQTSG VDKNRDKRKN NSGSGKPEQN VSKWSLSSAG KSKSNSRALL
KCSSTSKQCA VAHDDLKNSK NSSLNPCQEP PLKPTTTTQA TQPMARVVSR CLPPRSPMPV
SPIPLSFPEN PREEGKVPRT KKKCHRKSIL LNRAFYIQKR NCLSPSLIAR GKCSPTDQK