F218A_HUMAN
ID F218A_HUMAN Reviewed; 157 AA.
AC Q96MZ4;
DT 10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-2001, sequence version 1.
DT 03-AUG-2022, entry version 108.
DE RecName: Full=Protein FAM218A;
GN Name=FAM218A; Synonyms=C4orf39;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Teratocarcinoma;
RX PubMed=14702039; DOI=10.1038/ng1285;
RA Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
RA Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
RA Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
RA Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
RA Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H.,
RA Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M.,
RA Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K.,
RA Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T.,
RA Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M.,
RA Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S.,
RA Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H.,
RA Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K.,
RA Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N.,
RA Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
RA Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
RA Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
RA Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
RA Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y.,
RA Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K.,
RA Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T.,
RA Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T.,
RA Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y.,
RA Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H.,
RA Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y.,
RA Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H.,
RA Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O.,
RA Isogai T., Sugano S.;
RT "Complete sequencing and characterization of 21,243 full-length human
RT cDNAs.";
RL Nat. Genet. 36:40-45(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Prostate;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- INTERACTION:
CC Q96MZ4; Q9UHD4: CIDEB; NbExp=3; IntAct=EBI-10291578, EBI-7062247;
CC Q96MZ4; P25788: PSMA3; NbExp=3; IntAct=EBI-10291578, EBI-348380;
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DR EMBL; AK056221; BAB71123.1; -; mRNA.
DR EMBL; BC022381; AAH22381.1; -; mRNA.
DR RefSeq; NP_694572.1; NM_153027.1.
DR AlphaFoldDB; Q96MZ4; -.
DR BioGRID; 127464; 15.
DR IntAct; Q96MZ4; 2.
DR STRING; 9606.ENSP00000427428; -.
DR iPTMnet; Q96MZ4; -.
DR PhosphoSitePlus; Q96MZ4; -.
DR BioMuta; FAM218A; -.
DR PaxDb; Q96MZ4; -.
DR PeptideAtlas; Q96MZ4; -.
DR PRIDE; Q96MZ4; -.
DR ProteomicsDB; 77435; -.
DR DNASU; 152756; -.
DR UCSC; uc003iqx.2; human.
DR GeneCards; FAM218A; -.
DR HGNC; HGNC:26466; FAM218A.
DR neXtProt; NX_Q96MZ4; -.
DR PharmGKB; PA162379827; -.
DR HOGENOM; CLU_1677266_0_0_1; -.
DR InParanoid; Q96MZ4; -.
DR OrthoDB; 1268631at2759; -.
DR PathwayCommons; Q96MZ4; -.
DR SignaLink; Q96MZ4; -.
DR BioGRID-ORCS; 152756; 11 hits in 1065 CRISPR screens.
DR ChiTaRS; FAM218A; human.
DR GenomeRNAi; 152756; -.
DR Pharos; Q96MZ4; Tdark.
DR PRO; PR:Q96MZ4; -.
DR Proteomes; UP000005640; Chromosome 4.
DR RNAct; Q96MZ4; protein.
DR Genevisible; Q96MZ4; HS.
PE 1: Evidence at protein level;
KW Reference proteome.
FT CHAIN 1..157
FT /note="Protein FAM218A"
FT /id="PRO_0000340724"
FT REGION 104..127
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VARIANT 54
FT /note="H -> R (in dbSNP:rs3733418)"
FT /id="VAR_044025"
SQ SEQUENCE 157 AA; 17021 MW; 7DA9AE4F963BDF56 CRC64;
MEGCAVRRGS CPLLPGPSAW RASPAGWAGR AKLRSWCRAS GLPNRPYTLT GGRHGSVSLL
RHPGTTTFVQ QRSLHQSWEK RIVFSACPVS RSWCPERNFS GSIPAVTPPK LPGHSKSEGP
PGKVRKRTTI RSQPLFVTRT RGFGSAVGWL PLGSPVL
