ID   F221A_XENTR             Reviewed;         295 AA.
AC   Q28J59; Q0IIX0;
DT   10-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT   04-APR-2006, sequence version 1.
DT   03-AUG-2022, entry version 36.
DE   RecName: Full=Protein FAM221A;
GN   Name=fam221a; ORFNames=TNeu087m24.1;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Neurula;
RG   Sanger Xenopus tropicalis EST/cDNA project;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 2-295.
RC   STRAIN=N6; TISSUE=Liver;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the FAM221 family. {ECO:0000305}.
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DR   EMBL; CR760043; CAJ82435.1; -; mRNA.
DR   EMBL; BC121522; AAI21523.1; -; mRNA.
DR   RefSeq; NP_001016728.1; NM_001016728.2.
DR   AlphaFoldDB; Q28J59; -.
DR   GeneID; 549482; -.
DR   KEGG; xtr:549482; -.
DR   CTD; 340277; -.
DR   Xenbase; XB-GENE-1000335; fam221a.
DR   InParanoid; Q28J59; -.
DR   OrthoDB; 973186at2759; -.
DR   Proteomes; UP000008143; Chromosome 6.
DR   Proteomes; UP000790000; Unplaced.
DR   Bgee; ENSXETG00000017961; Expressed in testis and 14 other tissues.
DR   InterPro; IPR026755; Fam221a/b.
DR   PANTHER; PTHR31214; PTHR31214; 1.
DR   Pfam; PF14753; FAM221; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome.
FT   CHAIN           1..295
FT                   /note="Protein FAM221A"
FT                   /id="PRO_0000295143"
FT   REGION          272..295
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        272..287
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        211
FT                   /note="A -> T (in Ref. 2; AAI21523)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   295 AA;  33486 MW;  17A777DF68C467E5 CRC64;
     MEKLQFQGGA RAIDEYAEYR RIVGDDDGGK LFTPEEYEEY KKTVLPMRLQ NRLYVSWRSP
     TGMDCKLVGP ETPCFCTHRY KQHKTDFQEL PKERPLLLPC RVSKCACKSF HYIPLNGSRP
     IRCRCKHFAD EHSVAGTYHC TQCTKCSGFH SSFTCGCSQP AYTHDTVVET KEERLAQGKP
     VGHDVPFAAM GGLTGFSSLA EGYMRLDESG AGAPSTSFLE SSESGTSHPF LKMYYQPIKV
     QAVSEPSGIV TQVSNMRISE DDDMAYFERR YQERLLKEKE QKRQKNSKPP TTNRP