ID   F227B_RAT               Reviewed;         573 AA.
AC   Q6AXP3; Q5FVN5;
DT   27-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT   27-JUN-2006, sequence version 2.
DT   03-AUG-2022, entry version 88.
DE   RecName: Full=Protein FAM227B;
GN   Name=Fam227b;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SIMILARITY: Belongs to the FAM227 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAH79426.3; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
CC       Sequence=AAH89861.1; Type=Frameshift; Evidence={ECO:0000305};
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DR   EMBL; BC079426; AAH79426.3; ALT_INIT; mRNA.
DR   EMBL; BC089861; AAH89861.1; ALT_FRAME; mRNA.
DR   RefSeq; NP_001013942.2; NM_001013920.2.
DR   AlphaFoldDB; Q6AXP3; -.
DR   SMR; Q6AXP3; -.
DR   STRING; 10116.ENSRNOP00000052849; -.
DR   jPOST; Q6AXP3; -.
DR   PaxDb; Q6AXP3; -.
DR   PRIDE; Q6AXP3; -.
DR   Ensembl; ENSRNOT00000055995; ENSRNOP00000052849; ENSRNOG00000037124.
DR   GeneID; 296118; -.
DR   KEGG; rno:296118; -.
DR   UCSC; RGD:1359452; rat.
DR   CTD; 196951; -.
DR   RGD; 1359452; Fam227b.
DR   eggNOG; ENOG502RXR1; Eukaryota.
DR   GeneTree; ENSGT00940000162699; -.
DR   HOGENOM; CLU_028274_0_0_1; -.
DR   InParanoid; Q6AXP3; -.
DR   OMA; GITTESR; -.
DR   OrthoDB; 1153514at2759; -.
DR   PhylomeDB; Q6AXP3; -.
DR   TreeFam; TF328873; -.
DR   PRO; PR:Q6AXP3; -.
DR   Proteomes; UP000002494; Chromosome 3.
DR   Bgee; ENSRNOG00000037124; Expressed in testis and 19 other tissues.
DR   InterPro; IPR029417; FAM227.
DR   PANTHER; PTHR33560; PTHR33560; 1.
DR   Pfam; PF14922; FWWh; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Reference proteome.
FT   CHAIN           1..573
FT                   /note="Protein FAM227B"
FT                   /id="PRO_0000244101"
FT   REGION          497..528
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          429..485
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        498..522
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   573 AA;  67304 MW;  DA37A3CDE21192C5 CRC64;
     MELPTPQKVQ EPPKSFEEFL KSQNWDYWPR DVHIRDGDIW ENTLRKLEEA VSYNSVYSYL
     WTNVPRLYEI VDSMESKLKE CSHLLQQHAS RLFESDRLIS KKRTYTNLDR YKAFLKEHYR
     RKKIVLSDQM ETEKNIEGCT FLLKQNELTQ LPRHLDAKQI YLYVLRTHNL EEKVFKVWKT
     HILSDCSIAL LHDCFWWWFL HKFKPDKRDQ DWLFDRIAES YVTLFMRIPL RRKDIFFQMY
     PDWLAQAVYT TFQESFPESC SLFNDNFKED LGNTIFLWLS GLKPAPGFWT HWKLQDLCTT
     TIHGCRRVPV KLRRGIMSSQ EHTSATVGLK IEDILKNPRA LPVLKEESAA SKVTTKSHYR
     SLGPEFYKVL FDFGGQSPLI LYYLKMHELG GISVTYNPKG SKFTKILREP PPAPTYCEII
     KDAKRKFADN KKDFKRVKQR IKDDIKFLKE QQEQIDKELD RLQAKASKNL QEVKNDFENF
     LHKLRVEAKL KEEYRGSASP SESLQSLQSP NSSLSSPAMS EDFNSVEEGG LKEARSDHYL
     RTTHSSFSSI NLIGGECTTK STFCCSSLKS SHQ