ID   F234A_BOVIN             Reviewed;         552 AA.
AC   Q2HJE5;
DT   05-SEP-2006, integrated into UniProtKB/Swiss-Prot.
DT   21-MAR-2006, sequence version 1.
DT   03-AUG-2022, entry version 89.
DE   RecName: Full=Protein FAM234A;
DE   AltName: Full=Protein ITFG3;
GN   Name=FAM234A; Synonyms=ITFG3;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Uterus;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type II
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the FAM234 family. {ECO:0000305}.
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DR   EMBL; BC105518; AAI05519.1; -; mRNA.
DR   RefSeq; NP_001068786.1; NM_001075318.1.
DR   RefSeq; XP_005201040.1; XM_005200983.3.
DR   RefSeq; XP_005201041.1; XM_005200984.3.
DR   RefSeq; XP_005201042.1; XM_005200985.3.
DR   RefSeq; XP_005201043.1; XM_005200986.3.
DR   RefSeq; XP_005201044.1; XM_005200987.3.
DR   RefSeq; XP_010799078.1; XM_010800776.2.
DR   RefSeq; XP_015331337.1; XM_015475851.1.
DR   AlphaFoldDB; Q2HJE5; -.
DR   STRING; 9913.ENSBTAP00000022045; -.
DR   PaxDb; Q2HJE5; -.
DR   PRIDE; Q2HJE5; -.
DR   Ensembl; ENSBTAT00000022045; ENSBTAP00000022045; ENSBTAG00000016571.
DR   Ensembl; ENSBTAT00000076089; ENSBTAP00000059624; ENSBTAG00000016571.
DR   Ensembl; ENSBTAT00000086543; ENSBTAP00000064867; ENSBTAG00000016571.
DR   GeneID; 507493; -.
DR   KEGG; bta:507493; -.
DR   CTD; 83986; -.
DR   VEuPathDB; HostDB:ENSBTAG00000016571; -.
DR   VGNC; VGNC:97272; FAM234A.
DR   eggNOG; ENOG502R0CE; Eukaryota.
DR   GeneTree; ENSGT00530000063694; -.
DR   HOGENOM; CLU_036490_0_0_1; -.
DR   InParanoid; Q2HJE5; -.
DR   OMA; FMFWGLM; -.
DR   OrthoDB; 294858at2759; -.
DR   TreeFam; TF327203; -.
DR   Proteomes; UP000009136; Chromosome 25.
DR   Bgee; ENSBTAG00000016571; Expressed in esophagus and 105 other tissues.
DR   ExpressionAtlas; Q2HJE5; baseline.
DR   GO; GO:0009986; C:cell surface; IBA:GO_Central.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.130.10.10; -; 1.
DR   InterPro; IPR045232; FAM234.
DR   InterPro; IPR002372; PQQ_repeat.
DR   InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   PANTHER; PTHR21419; PTHR21419; 1.
DR   Pfam; PF13360; PQQ_2; 1.
DR   SUPFAM; SSF50998; SSF50998; 1.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Membrane; Reference proteome; Signal-anchor; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..552
FT                   /note="Protein FAM234A"
FT                   /id="PRO_0000247992"
FT   TOPO_DOM        1..48
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        49..69
FT                   /note="Helical; Signal-anchor for type II membrane protein"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        70..552
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        115
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        238
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        473
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   552 AA;  58767 MW;  4F7A628592DE9AAB CRC64;
     MTDGKDLEAE IHPLKSENRK VPENAGALAG KEPRGTPAPQ TRLSHCRTAA FFLSLFACLL
     VVFVVSFIIP CPDRPALQGV WRIDYNAAVA YDFLAAEDVN KDKIQDILFL YKNTNSSRGN
     SSFSCADEGF SCPCTFVAAV SGASGSVLWE RPVAQDRAFV ECGILQPRGS AAPSACVVLG
     RPGSLVAVDT LTGKTLWSQP SSFGGNASVL SPLLRVPDLD ADGAPDLLVL IQEENQVNGS
     IYSGGTGQQV SPPDSLGVDG TSGSILHVTR AGAHYVLIPC GTALCSRSVK GLYEKVSRRD
     SPLKSDPLWE DMLSAASHRL VVHSSGAIRY LMNVPGKAGD DLLLVSTEAY MLLDGQDLTP
     RWTFGTTQVL RKPVLGYYKP DTPAVLVENG TGPDRQVLLL DLGSGAVLWS QALPGLPGDP
     PSASLPTADH RSAFFFWGIH EPTDSNQTEP GAAGRRLYML HPTLPGVLLE LDNVSVPIVA
     FQVVLLEPGR HAACILLTGP ASPSPPGLVS VTKHKVQDLV LAGRVVHLAE GGAESDQAVR
     DRLSRLRYRS EA