ID   F234A_RAT               Reviewed;         552 AA.
AC   Q5M7W6;
DT   05-SEP-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-2005, sequence version 1.
DT   03-AUG-2022, entry version 101.
DE   RecName: Full=Protein FAM234A;
DE   AltName: Full=Protein ITFG3;
GN   Name=Fam234a; Synonyms=Itfg3;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Brown Norway; TISSUE=Kidney;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
RN   [2]
RP   PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-21, AND IDENTIFICATION BY
RP   MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=22673903; DOI=10.1038/ncomms1871;
RA   Lundby A., Secher A., Lage K., Nordsborg N.B., Dmytriyev A., Lundby C.,
RA   Olsen J.V.;
RT   "Quantitative maps of protein phosphorylation sites across 14 different rat
RT   organs and tissues.";
RL   Nat. Commun. 3:876-876(2012).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type II
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the FAM234 family. {ECO:0000305}.
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DR   EMBL; BC088404; AAH88404.1; -; mRNA.
DR   RefSeq; NP_001009701.1; NM_001009701.1.
DR   AlphaFoldDB; Q5M7W6; -.
DR   STRING; 10116.ENSRNOP00000030807; -.
DR   GlyGen; Q5M7W6; 4 sites.
DR   iPTMnet; Q5M7W6; -.
DR   PhosphoSitePlus; Q5M7W6; -.
DR   PaxDb; Q5M7W6; -.
DR   PRIDE; Q5M7W6; -.
DR   Ensembl; ENSRNOT00000120131; ENSRNOP00000097833; ENSRNOG00000067554.
DR   GeneID; 360502; -.
DR   KEGG; rno:360502; -.
DR   UCSC; RGD:1311484; rat.
DR   CTD; 83986; -.
DR   RGD; 1311484; Fam234a.
DR   eggNOG; ENOG502R0CE; Eukaryota.
DR   GeneTree; ENSGT00530000063694; -.
DR   InParanoid; Q5M7W6; -.
DR   PhylomeDB; Q5M7W6; -.
DR   TreeFam; TF327203; -.
DR   PRO; PR:Q5M7W6; -.
DR   Proteomes; UP000002494; Chromosome 10.
DR   GO; GO:0009986; C:cell surface; ISO:RGD.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR045232; FAM234.
DR   InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR   PANTHER; PTHR21419; PTHR21419; 1.
DR   SUPFAM; SSF50998; SSF50998; 1.
PE   1: Evidence at protein level;
KW   Glycoprotein; Membrane; Phosphoprotein; Reference proteome; Signal-anchor;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..552
FT                   /note="Protein FAM234A"
FT                   /id="PRO_0000247995"
FT   TOPO_DOM        1..49
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        50..70
FT                   /note="Helical; Signal-anchor for type II membrane protein"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        71..552
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   REGION          1..40
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..26
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         21
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0007744|PubMed:22673903"
FT   CARBOHYD        116
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        119
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        314
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        473
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   552 AA;  60637 MW;  1EA25EDFC289729E CRC64;
     MMDDKDLEAE IHPLKNEDKK SQENLGNLPK TEDNLKNKPV PSRLSRCRTV AFFLSLFICL
     FVVFVLSFII PCPDRPSSED KWRLDYDYAV TYDFLALGDV DRDEVQDVLF LYKNTNSSNN
     STRSCADEGF STPCTFMAAV SGTNGTVLWE RPLAQDVAHV KCAVPQTRDS KVSSACVLVG
     RLGSFMAVNF FTGETLWSHP RSFSGNASIL SPLLQVPDID GDGAPDLLML SREGQEVSGA
     LYSGSTGYQI GHRGSLGVDG DGVALLHVTR TGAQYILLPC ASALCGVSVK GLYKRITGRD
     DHFKEDPSWE NMLNRSAHRR LLHSSGAVRY LMNVPGKTGQ DLLLVSSEDC KLLDGQDLVP
     RWTLGATQVL RKPILGHYKP DTLAVVIENG TSLDRQILLL DLSTGSMLWS QPLPSLPGAP
     PSTSLMTADH RSAFFFWGLH DPVSANEMDP QDTQHSLYMF HPTLPGILLE LANVSANIVA
     FDAVLFEPSR HAAYVLLTGP ASSDVPGLVS LTKHRVRDLV PGSRVIHLSE GSSDSDQAIR
     DRFSRLRYRS EV