F237A_HUMAN
ID F237A_HUMAN Reviewed; 181 AA.
AC A0A1B0GTK4;
DT 07-JUN-2017, integrated into UniProtKB/Swiss-Prot.
DT 05-OCT-2016, sequence version 1.
DT 03-AUG-2022, entry version 31.
DE RecName: Full=Protein FAM237A {ECO:0000305};
GN Name=FAM237A {ECO:0000312|HGNC:HGNC:52388};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15815621; DOI=10.1038/nature03466;
RA Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P.,
RA Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C.,
RA Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L.,
RA Du H., Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A.,
RA Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J.,
RA Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M.,
RA Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T.,
RA Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S.,
RA Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K.,
RA McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C.,
RA Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S.,
RA Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C.,
RA Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M.,
RA Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C.,
RA Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J.,
RA Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E.,
RA Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X.,
RA Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M.,
RA Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C.,
RA Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S.,
RA Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H.,
RA Wilson R.K.;
RT "Generation and annotation of the DNA sequences of human chromosomes 2 and
RT 4.";
RL Nature 434:724-731(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M.,
RA Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J.,
RA Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S.,
RA Turner R., Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H.,
RA Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K.,
RA Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D.,
RA Hunkapiller M.W., Myers E.W., Venter J.C.;
RL Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Single-pass membrane
CC protein {ECO:0000255}.
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DR EMBL; AC010731; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CH471063; EAW70389.1; -; Genomic_DNA.
DR CCDS; CCDS82560.1; -.
DR RefSeq; NP_001096129.1; NM_001102659.2.
DR AlphaFoldDB; A0A1B0GTK4; -.
DR BioMuta; FAM237A; -.
DR MassIVE; A0A1B0GTK4; -.
DR PeptideAtlas; A0A1B0GTK4; -.
DR Antibodypedia; 78617; 2 antibodies from 2 providers.
DR DNASU; 200726; -.
DR Ensembl; ENST00000441223.4; ENSP00000490802.1; ENSG00000235118.9.
DR GeneID; 200726; -.
DR KEGG; hsa:200726; -.
DR MANE-Select; ENST00000441223.4; ENSP00000490802.1; NM_001102659.3; NP_001096129.1.
DR CTD; 200726; -.
DR GeneCards; FAM237A; -.
DR HGNC; HGNC:52388; FAM237A.
DR HPA; ENSG00000235118; Not detected.
DR neXtProt; NX_A0A1B0GTK4; -.
DR VEuPathDB; HostDB:ENSG00000235118; -.
DR GeneTree; ENSGT00390000015769; -.
DR OMA; CTMRLTC; -.
DR OrthoDB; 1367940at2759; -.
DR BioGRID-ORCS; 200726; 9 hits in 166 CRISPR screens.
DR GenomeRNAi; 200726; -.
DR Pharos; A0A1B0GTK4; Tdark.
DR PRO; PR:A0A1B0GTK4; -.
DR Proteomes; UP000005640; Chromosome 2.
DR RNAct; A0A1B0GTK4; protein.
DR Bgee; ENSG00000235118; Expressed in primary visual cortex and 49 other tissues.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR InterPro; IPR040439; FAM237A/B.
DR PANTHER; PTHR36690; PTHR36690; 1.
PE 3: Inferred from homology;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..181
FT /note="Protein FAM237A"
FT /id="PRO_0000440611"
FT TRANSMEM 14..30
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 181 AA; 20560 MW; A7D43C0C1FE19EC7 CRC64;
MADPGNRGGI HRPLSFTCSL LIVGMCCVSP FFCHSQTDLL ALSQADPQCW ESSSVLLLEM
WKPRVSNTVS GFWDFMIYLK SSENLKHGAL FWDLAQLFWD IYVDCVLSRN HGLGRRQLVG
EEEKISAAQP QHTRSKQGTY SQLLRTSFLK KKELIEDLIS MHVRRSGSSV IGKVNLEIKR
K