ID   F50AA_XENLA             Reviewed;         340 AA.
AC   Q2VPH1; Q8AVT5;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   10-JAN-2006, sequence version 1.
DT   03-AUG-2022, entry version 39.
DE   RecName: Full=Protein FAM50A-A;
GN   Name=fam50a-a; Synonyms=fam50-a;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Eye, and Neurula;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Probably involved in the regulation of pre-mRNA splicing.
CC       {ECO:0000250|UniProtKB:Q568K9}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q14320}.
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DR   EMBL; BC041272; AAH41272.1; -; mRNA.
DR   EMBL; BC108795; AAI08796.1; -; mRNA.
DR   RefSeq; NP_001080084.1; NM_001086615.1.
DR   AlphaFoldDB; Q2VPH1; -.
DR   PRIDE; Q2VPH1; -.
DR   DNASU; 379776; -.
DR   GeneID; 379776; -.
DR   KEGG; xla:379776; -.
DR   CTD; 379776; -.
DR   Xenbase; XB-GENE-970300; fam50a.L.
DR   OrthoDB; 1061864at2759; -.
DR   Proteomes; UP000186698; Chromosome 8L.
DR   Bgee; 379776; Expressed in lung and 19 other tissues.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR   InterPro; IPR007005; XAP5.
DR   PANTHER; PTHR12722; PTHR12722; 1.
DR   Pfam; PF04921; XAP5; 1.
PE   2: Evidence at transcript level;
KW   mRNA processing; mRNA splicing; Nucleus; Reference proteome.
FT   CHAIN           1..340
FT                   /note="Protein FAM50A-A"
FT                   /id="PRO_0000326509"
FT   REGION          1..22
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          123..178
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        124..143
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        158..178
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        156
FT                   /note="Missing (in Ref. 1; AAH41272)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   340 AA;  40334 MW;  90034E03E636CC57 CRC64;
     MAQYKGAASE AGRAMQLMKK REKQREQLEQ MKLKIAEENV VKANINKKFS AHYDAVEAEL
     KSSTVGLVTL NDMKAKQEAL VKEREKQLAK KEQFKDLQLM LEKQRERERK KEQKRKIASL
     SFNLEEDEEC EDEEGEEEES DKEDPPEEKK KKKKKKLGKN PDVDTSFLPD RDREEEENRL
     REELRQEWEH KQEKIKSEEI EITFSYWDGS GHRRTVKMKK GNSIQQFLQK ALESLRKDFS
     ELRSAGVEQL MYIKEDLIIP HHHSFYDFIV TKARGKSGPL FNFDVHEDVR LLSDATVEKD
     ESHAGKVVLR SWYEKNKHIF PASRWEPYDP EKKWDKYTIR