F50AB_XENLA
ID F50AB_XENLA Reviewed; 343 AA.
AC Q4KLV7;
DT 08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 02-AUG-2005, sequence version 1.
DT 03-AUG-2022, entry version 35.
DE RecName: Full=Protein FAM50A-B;
GN Name=fam50a-b; Synonyms=fam50-b;
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Ovary;
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Probably involved in the regulation of pre-mRNA splicing.
CC {ECO:0000250|UniProtKB:Q568K9}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q14320}.
CC -!- SIMILARITY: Belongs to the FAM50 family. {ECO:0000305}.
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DR EMBL; BC098980; AAH98980.1; -; mRNA.
DR RefSeq; NP_001089573.1; NM_001096104.1.
DR AlphaFoldDB; Q4KLV7; -.
DR DNASU; 734629; -.
DR GeneID; 734629; -.
DR KEGG; xla:734629; -.
DR CTD; 734629; -.
DR OrthoDB; 1061864at2759; -.
DR Proteomes; UP000186698; Chromosome 8S.
DR Bgee; 734629; Expressed in gastrula and 19 other tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR InterPro; IPR007005; XAP5.
DR PANTHER; PTHR12722; PTHR12722; 1.
DR Pfam; PF04921; XAP5; 1.
PE 2: Evidence at transcript level;
KW mRNA processing; mRNA splicing; Nucleus; Reference proteome.
FT CHAIN 1..343
FT /note="Protein FAM50A-B"
FT /id="PRO_0000326510"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 125..181
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 125..144
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 343 AA; 40782 MW; 96D546CBC947569D CRC64;
MAQYKGAASE AGRAMQLMKK REKQREQLEQ MKLKIAEENV VKANINKKFS AHYDAVEAEL
KSSTVGLVTL NDMKAKQEAL VKEREKQLAK KEQFKDLQLK LEKQRERERK KEQKRKIASL
SFNLEEDEEC EDEESEEEEE EYVADKEDLP KKKKKKKQQL GKNPDVDTSF LPDRDREEEE
NRLREELRQE WERKQEKIKS EEIEITFSYW DGSGHRRTVK MKKGNSIQQF LQKALEILRK
DFSELRSAGV EQLMYIKEDL IIPHHHSFYD FIVTKARGKS GPLFNFDVHE DVRLLSDASV
EKDESHAGKV VLRSWYEKNK HIFPASRWEP YDPEKKWDKY TIR