ID   F5_VACCW                Reviewed;         322 AA.
AC   P24358; Q76ZX0;
DT   01-MAR-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-1992, sequence version 1.
DT   25-MAY-2022, entry version 89.
DE   RecName: Full=36 kDa major membrane protein F5;
DE   Flags: Precursor;
GN   OrderedLocusNames=VACWR044; ORFNames=F5L;
OS   Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain
OS   WR)).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus; Vaccinia virus.
OX   NCBI_TaxID=10254;
OH   NCBI_TaxID=9913; Bos taurus (Bovine).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=2219701; DOI=10.1016/0042-6822(90)90338-r;
RA   Roseman N.A., Slabaugh M.B.;
RT   "The vaccinia virus HindIII F fragment: nucleotide sequence of the left 6.2
RT   kb.";
RL   Virology 178:410-418(1990).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Esposito J.J., Frace A.M., Sammons S.A., Olsen-Rasmussen M., Osborne J.,
RA   Wohlhueter R.;
RT   "Sequencing of the coding region of Vaccinia-WR to an average 9-fold
RT   redundancy and an error rate of 0.16/10kb.";
RL   Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the poxviridae F5 protein family. {ECO:0000305}.
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DR   EMBL; M34368; AAA48243.1; -; mRNA.
DR   EMBL; AY243312; AAO89323.1; -; Genomic_DNA.
DR   PIR; E36213; E36213.
DR   RefSeq; YP_232926.1; NC_006998.1.
DR   SMR; P24358; -.
DR   DNASU; 3707501; -.
DR   GeneID; 3707501; -.
DR   KEGG; vg:3707501; -.
DR   Proteomes; UP000000344; Genome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016032; P:viral process; IEA:InterPro.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR007674; Poxvirus_36kDa_major_membrane.
DR   Pfam; PF04595; Pox_I6; 1.
DR   SUPFAM; SSF48726; SSF48726; 1.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Membrane; Reference proteome; Signal; Transmembrane;
KW   Transmembrane helix.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000255"
FT   CHAIN           21..322
FT                   /note="36 kDa major membrane protein F5"
FT                   /id="PRO_0000040616"
FT   TRANSMEM        287..307
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        36
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        41
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        72
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        79
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        108
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        144
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        220
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        246
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   322 AA;  36600 MW;  D6CE2CEE2EAE76C2 CRC64;
     MGTNGVRVFV ILYLLAVCGC IEYDVDDNVH ICTHTNVSHI NHTSWYYNDK VIALATEDKT
     SGYISSFIKR VNISLTCLNI SSLRYEDSGT YKGVSHLKDG VIVTTTMNIS VKANIIDLTG
     RVRYLTRNYC EVKIRCEITS FALNGSTTPP HMILGTVDKW KYLPFPTDDY RYVGELKRYI
     SGNPYPTESL ALEISSTFNR FTIVKNLNDD EFSCYLFSQN YSFHKMLNVR NICESEWEAL
     NNNNDNSSSM PASHNNLAND LSSMMSQLQN DNDDNNDYSA PMNVDNLIMI VLITMLSIIL
     VIIVVIAAIS MYKRSKYRHI DN