ID   F83DA_XENLA             Reviewed;         562 AA.
AC   Q5XGY0;
DT   03-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   25-MAY-2022, entry version 54.
DE   RecName: Full=Protein FAM83D-A {ECO:0000305};
GN   Name=fam83d-a {ECO:0000250|UniProtKB:Q9H4H8};
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May regulate cell proliferation, growth, migration and
CC       epithelial to mesenchymal transition. May also be important for proper
CC       chromosome congression and alignment during mitosis.
CC       {ECO:0000250|UniProtKB:Q9H4H8}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q9H4H8}.
CC       Cytoplasm, cytoskeleton, spindle {ECO:0000250|UniProtKB:Q9H4H8}.
CC       Cytoplasm, cytoskeleton, spindle pole {ECO:0000250|UniProtKB:Q9H4H8}.
CC   -!- SIMILARITY: Belongs to the FAM83 family. {ECO:0000305}.
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DR   EMBL; BC084297; AAH84297.1; -; mRNA.
DR   AlphaFoldDB; Q5XGY0; -.
DR   SMR; Q5XGY0; -.
DR   Proteomes; UP000186698; Genome assembly.
DR   GO; GO:0005737; C:cytoplasm; ISS:UniProtKB.
DR   GO; GO:0097431; C:mitotic spindle pole; ISS:UniProtKB.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0008283; P:cell population proliferation; ISS:UniProtKB.
DR   GO; GO:0051310; P:metaphase plate congression; ISS:UniProtKB.
DR   GO; GO:0070372; P:regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.
DR   InterPro; IPR012461; FAM83_N.
DR   Pfam; PF07894; FAM83; 1.
PE   2: Evidence at transcript level;
KW   Cell cycle; Cell division; Cytoplasm; Cytoskeleton; Mitosis;
KW   Reference proteome.
FT   CHAIN           1..562
FT                   /note="Protein FAM83D-A"
FT                   /id="PRO_0000365010"
FT   REGION          424..471
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   562 AA;  62433 MW;  1954C42E1402B726 CRC64;
     MANASQCLDD VPMGGRWPAA PPDQYNEAHR LAMEELVSGG PEAMRGFLKR ERLPSFLSEP
     EMGEILGCAS VLPCGDEENS MSASVDCSSV TYFPDRSDVE PPILELGWPA FTTGSYRGVT
     RVDVHFQPSF GDTIYTCKEA ARELIRSARE VIALVMDNFT DNDIFRDIHE ACRKRRVPVY
     ILLDQTQVSH FLTMCYNLGV SIETEPHMRV RLLTGNHYYT RSGTKIIGKV REKFLLVDGV
     KVATGNYSFT WTDGKLNSSN MLVLSGQVVE KFDLQFRILY AQSNPIGAKL LSSIRSRAMC
     LDKLPCKLPA SKKPTLSSLL RMDQAKLSST PKRHFDEFGA KFNRDVVALD KAAEDEWLQS
     CDIISGLKEM QTVEVQTEPW EGKNNVRGVD VGIQTSVAAA NAATQTSVLS RMASTQTVMV
     SRSITTQTTE TSQCTTQTPA PTSSVARLSN SSNSSSSSFS STSITSTGSN CSMKSSDFSG
     TAFYQPEYPL GNCFKKLTKD RQYHYSTIRS KLNHMVSILS NRNRMPNSYM ANDAPCYGLQ
     RREIMHGSLL NLRDGVRFYP NM