F90A1_HUMAN
ID F90A1_HUMAN Reviewed; 464 AA.
AC Q86YD7; D3DUU9; Q9NVZ6;
DT 11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT 24-NOV-2009, sequence version 3.
DT 03-AUG-2022, entry version 128.
DE RecName: Full=Protein FAM90A1;
GN Name=FAM90A1;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], AND VARIANTS GLY-123 AND ILE-348.
RX PubMed=14702039; DOI=10.1038/ng1285;
RA Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
RA Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
RA Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
RA Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
RA Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H.,
RA Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M.,
RA Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K.,
RA Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T.,
RA Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M.,
RA Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S.,
RA Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H.,
RA Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K.,
RA Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N.,
RA Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
RA Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
RA Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
RA Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
RA Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y.,
RA Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K.,
RA Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T.,
RA Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T.,
RA Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y.,
RA Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H.,
RA Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y.,
RA Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H.,
RA Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O.,
RA Isogai T., Sugano S.;
RT "Complete sequencing and characterization of 21,243 full-length human
RT cDNAs.";
RL Nat. Genet. 36:40-45(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16541075; DOI=10.1038/nature04569;
RA Scherer S.E., Muzny D.M., Buhay C.J., Chen R., Cree A., Ding Y.,
RA Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C.,
RA Hernandez J., Hodgson A.V., Hume J., Jackson A., Khan Z.M., Kovar-Smith C.,
RA Lewis L.R., Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R.,
RA Montgomery K.T., Morgan M.B., Nazareth L.V., Scott G., Sodergren E.,
RA Song X.-Z., Steffen D., Lovering R.C., Wheeler D.A., Worley K.C., Yuan Y.,
RA Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G.,
RA Chen Z., Clerc-Blankenburg K.P., Davis C., Delgado O., Dinh H.H.,
RA Draper H., Gonzalez-Garay M.L., Havlak P., Jackson L.R., Jacob L.S.,
RA Kelly S.H., Li L., Li Z., Liu J., Liu W., Lu J., Maheshwari M.,
RA Nguyen B.-V., Okwuonu G.O., Pasternak S., Perez L.M., Plopper F.J.H.,
RA Santibanez J., Shen H., Tabor P.E., Verduzco D., Waldron L., Wang Q.,
RA Williams G.A., Zhang J., Zhou J., Allen C.C., Amin A.G., Anyalebechi V.,
RA Bailey M., Barbaria J.A., Bimage K.E., Bryant N.P., Burch P.E.,
RA Burkett C.E., Burrell K.L., Calderon E., Cardenas V., Carter K., Casias K.,
RA Cavazos I., Cavazos S.R., Ceasar H., Chacko J., Chan S.N., Chavez D.,
RA Christopoulos C., Chu J., Cockrell R., Cox C.D., Dang M., Dathorne S.R.,
RA David R., Davis C.M., Davy-Carroll L., Deshazo D.R., Donlin J.E.,
RA D'Souza L., Eaves K.A., Egan A., Emery-Cohen A.J., Escotto M., Flagg N.,
RA Forbes L.D., Gabisi A.M., Garza M., Hamilton C., Henderson N.,
RA Hernandez O., Hines S., Hogues M.E., Huang M., Idlebird D.G., Johnson R.,
RA Jolivet A., Jones S., Kagan R., King L.M., Leal B., Lebow H., Lee S.,
RA LeVan J.M., Lewis L.C., London P., Lorensuhewa L.M., Loulseged H.,
RA Lovett D.A., Lucier A., Lucier R.L., Ma J., Madu R.C., Mapua P.,
RA Martindale A.D., Martinez E., Massey E., Mawhiney S., Meador M.G.,
RA Mendez S., Mercado C., Mercado I.C., Merritt C.E., Miner Z.L., Minja E.,
RA Mitchell T., Mohabbat F., Mohabbat K., Montgomery B., Moore N., Morris S.,
RA Munidasa M., Ngo R.N., Nguyen N.B., Nickerson E., Nwaokelemeh O.O.,
RA Nwokenkwo S., Obregon M., Oguh M., Oragunye N., Oviedo R.J., Parish B.J.,
RA Parker D.N., Parrish J., Parks K.L., Paul H.A., Payton B.A., Perez A.,
RA Perrin W., Pickens A., Primus E.L., Pu L.-L., Puazo M., Quiles M.M.,
RA Quiroz J.B., Rabata D., Reeves K., Ruiz S.J., Shao H., Sisson I.,
RA Sonaike T., Sorelle R.P., Sutton A.E., Svatek A.F., Svetz L.A.,
RA Tamerisa K.S., Taylor T.R., Teague B., Thomas N., Thorn R.D., Trejos Z.Y.,
RA Trevino B.K., Ukegbu O.N., Urban J.B., Vasquez L.I., Vera V.A.,
RA Villasana D.M., Wang L., Ward-Moore S., Warren J.T., Wei X., White F.,
RA Williamson A.L., Wleczyk R., Wooden H.S., Wooden S.H., Yen J., Yoon L.,
RA Yoon V., Zorrilla S.E., Nelson D., Kucherlapati R., Weinstock G.,
RA Gibbs R.A.;
RT "The finished DNA sequence of human chromosome 12.";
RL Nature 440:346-351(2006).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND VARIANT ILE-348.
RA Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M.,
RA Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J.,
RA Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S.,
RA Turner R., Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H.,
RA Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K.,
RA Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D.,
RA Hunkapiller M.W., Myers E.W., Venter J.C.;
RL Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], AND VARIANTS GLY-123; GLU-234;
RP LEU-334 AND ILE-348.
RC TISSUE=Brain;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- INTERACTION:
CC Q86YD7; Q9NYB9-2: ABI2; NbExp=3; IntAct=EBI-6658203, EBI-11096309;
CC Q86YD7; Q08043: ACTN3; NbExp=3; IntAct=EBI-6658203, EBI-2880652;
CC Q86YD7; Q6PJH3: AKAP9; NbExp=3; IntAct=EBI-6658203, EBI-11745576;
CC Q86YD7; Q9Y2J4: AMOTL2; NbExp=3; IntAct=EBI-6658203, EBI-746752;
CC Q86YD7; Q86SG2: ANKRD23; NbExp=3; IntAct=EBI-6658203, EBI-5661893;
CC Q86YD7; Q8N6D5: ANKRD29; NbExp=3; IntAct=EBI-6658203, EBI-17439331;
CC Q86YD7; Q96CW1: AP2M1; NbExp=5; IntAct=EBI-6658203, EBI-297683;
CC Q86YD7; O43307: ARHGEF9; NbExp=3; IntAct=EBI-6658203, EBI-3447299;
CC Q86YD7; Q96B67: ARRDC3; NbExp=3; IntAct=EBI-6658203, EBI-2875665;
CC Q86YD7; Q8N9N5: BANP; NbExp=3; IntAct=EBI-6658203, EBI-744695;
CC Q86YD7; Q8N9N5-2: BANP; NbExp=3; IntAct=EBI-6658203, EBI-11524452;
CC Q86YD7; P56945: BCAR1; NbExp=3; IntAct=EBI-6658203, EBI-702093;
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CC Q86YD7; Q6PI77: BHLHB9; NbExp=3; IntAct=EBI-6658203, EBI-11519926;
CC Q86YD7; Q9H2G9: BLZF1; NbExp=3; IntAct=EBI-6658203, EBI-2548012;
CC Q86YD7; O60885: BRD4; NbExp=5; IntAct=EBI-6658203, EBI-723869;
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CC Q86YD7; Q13137: CALCOCO2; NbExp=7; IntAct=EBI-6658203, EBI-739580;
CC Q86YD7; Q9H257-2: CARD9; NbExp=3; IntAct=EBI-6658203, EBI-11530605;
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CC Q86YD7; Q8TAP6: CEP76; NbExp=6; IntAct=EBI-6658203, EBI-742887;
CC Q86YD7; Q6WN34-2: CHRDL2; NbExp=3; IntAct=EBI-6658203, EBI-12593838;
CC Q86YD7; Q9Y2V7: COG6; NbExp=5; IntAct=EBI-6658203, EBI-3866319;
CC Q86YD7; A8MQ03: CYSRT1; NbExp=3; IntAct=EBI-6658203, EBI-3867333;
CC Q86YD7; Q8N9I9: DTX3; NbExp=5; IntAct=EBI-6658203, EBI-2340258;
CC Q86YD7; Q92997: DVL3; NbExp=3; IntAct=EBI-6658203, EBI-739789;
CC Q86YD7; O95967: EFEMP2; NbExp=3; IntAct=EBI-6658203, EBI-743414;
CC Q86YD7; Q9H0I2: ENKD1; NbExp=3; IntAct=EBI-6658203, EBI-744099;
CC Q86YD7; Q96B26: EXOSC8; NbExp=6; IntAct=EBI-6658203, EBI-371922;
CC Q86YD7; Q86W67: FAM228A; NbExp=3; IntAct=EBI-6658203, EBI-12958227;
CC Q86YD7; Q13643: FHL3; NbExp=7; IntAct=EBI-6658203, EBI-741101;
CC Q86YD7; Q96C98: FHL3; NbExp=3; IntAct=EBI-6658203, EBI-10229248;
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CC Q86YD7; P51114-2: FXR1; NbExp=3; IntAct=EBI-6658203, EBI-11022345;
CC Q86YD7; P51116: FXR2; NbExp=3; IntAct=EBI-6658203, EBI-740459;
CC Q86YD7; P06241-3: FYN; NbExp=3; IntAct=EBI-6658203, EBI-10691738;
CC Q86YD7; Q06547: GABPB1; NbExp=3; IntAct=EBI-6658203, EBI-618165;
CC Q86YD7; Q5JQS6: GCSAML; NbExp=3; IntAct=EBI-6658203, EBI-17857617;
CC Q86YD7; Q3T906: GNPTAB; NbExp=3; IntAct=EBI-6658203, EBI-1104907;
CC Q86YD7; Q08379: GOLGA2; NbExp=8; IntAct=EBI-6658203, EBI-618309;
CC Q86YD7; Q9HD26: GOPC; NbExp=3; IntAct=EBI-6658203, EBI-349832;
CC Q86YD7; Q86YR5-3: GPSM1; NbExp=3; IntAct=EBI-6658203, EBI-10261098;
CC Q86YD7; Q4V328: GRIPAP1; NbExp=3; IntAct=EBI-6658203, EBI-717919;
CC Q86YD7; P61296-2: HAND2; NbExp=3; IntAct=EBI-6658203, EBI-13086076;
CC Q86YD7; Q6NT76: HMBOX1; NbExp=3; IntAct=EBI-6658203, EBI-2549423;
CC Q86YD7; Q9NSC5: HOMER3; NbExp=3; IntAct=EBI-6658203, EBI-748420;
CC Q86YD7; Q96ED9-2: HOOK2; NbExp=3; IntAct=EBI-6658203, EBI-10961706;
CC Q86YD7; O75031: HSF2BP; NbExp=3; IntAct=EBI-6658203, EBI-7116203;
CC Q86YD7; Q9ULR0: ISY1; NbExp=3; IntAct=EBI-6658203, EBI-2557660;
CC Q86YD7; Q63ZY3: KANK2; NbExp=3; IntAct=EBI-6658203, EBI-2556193;
CC Q86YD7; Q8N6L0: KASH5; NbExp=3; IntAct=EBI-6658203, EBI-749265;
CC Q86YD7; Q9BVG8-5: KIFC3; NbExp=3; IntAct=EBI-6658203, EBI-14069005;
CC Q86YD7; Q53G59: KLHL12; NbExp=3; IntAct=EBI-6658203, EBI-740929;
CC Q86YD7; O00505: KPNA3; NbExp=4; IntAct=EBI-6658203, EBI-358297;
CC Q86YD7; O60684: KPNA6; NbExp=3; IntAct=EBI-6658203, EBI-359923;
CC Q86YD7; Q15323: KRT31; NbExp=6; IntAct=EBI-6658203, EBI-948001;
CC Q86YD7; O76011: KRT34; NbExp=3; IntAct=EBI-6658203, EBI-1047093;
CC Q86YD7; O76015: KRT38; NbExp=3; IntAct=EBI-6658203, EBI-1047263;
CC Q86YD7; Q6A162: KRT40; NbExp=6; IntAct=EBI-6658203, EBI-10171697;
CC Q86YD7; Q07627: KRTAP1-1; NbExp=3; IntAct=EBI-6658203, EBI-11959885;
CC Q86YD7; P60410: KRTAP10-8; NbExp=3; IntAct=EBI-6658203, EBI-10171774;
CC Q86YD7; O95751: LDOC1; NbExp=6; IntAct=EBI-6658203, EBI-740738;
CC Q86YD7; Q9UPM6: LHX6; NbExp=3; IntAct=EBI-6658203, EBI-10258746;
CC Q86YD7; P48059-3: LIMS1; NbExp=3; IntAct=EBI-6658203, EBI-12864460;
CC Q86YD7; P25791-3: LMO2; NbExp=5; IntAct=EBI-6658203, EBI-11959475;
CC Q86YD7; Q8TBB1: LNX1; NbExp=3; IntAct=EBI-6658203, EBI-739832;
CC Q86YD7; Q9P2M1: LRP2BP; NbExp=3; IntAct=EBI-6658203, EBI-18273118;
CC Q86YD7; Q9Y250: LZTS1; NbExp=3; IntAct=EBI-6658203, EBI-1216080;
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CC Q86YD7; Q99750: MDFI; NbExp=3; IntAct=EBI-6658203, EBI-724076;
CC Q86YD7; Q99687-3: MEIS3; NbExp=3; IntAct=EBI-6658203, EBI-18582591;
CC Q86YD7; Q9UJV3-2: MID2; NbExp=6; IntAct=EBI-6658203, EBI-10172526;
CC Q86YD7; Q8TD10: MIPOL1; NbExp=3; IntAct=EBI-6658203, EBI-2548751;
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CC Q86YD7; Q6PF18: MORN3; NbExp=3; IntAct=EBI-6658203, EBI-9675802;
CC Q86YD7; Q4VC12: MSS51; NbExp=3; IntAct=EBI-6658203, EBI-11599933;
CC Q86YD7; Q5JR59: MTUS2; NbExp=3; IntAct=EBI-6658203, EBI-742948;
CC Q86YD7; Q5JR59-3: MTUS2; NbExp=3; IntAct=EBI-6658203, EBI-11522433;
CC Q86YD7; P15173: MYOG; NbExp=3; IntAct=EBI-6658203, EBI-3906629;
CC Q86YD7; P17568: NDUFB7; NbExp=3; IntAct=EBI-6658203, EBI-1246238;
CC Q86YD7; P0DPK4: NOTCH2NLC; NbExp=3; IntAct=EBI-6658203, EBI-22310682;
CC Q86YD7; O43809: NUDT21; NbExp=3; IntAct=EBI-6658203, EBI-355720;
CC Q86YD7; O14753: OVOL1; NbExp=3; IntAct=EBI-6658203, EBI-3917713;
CC Q86YD7; P40424: PBX1; NbExp=3; IntAct=EBI-6658203, EBI-301611;
CC Q86YD7; P40425: PBX2; NbExp=3; IntAct=EBI-6658203, EBI-348489;
CC Q86YD7; Q9NR12: PDLIM7; NbExp=3; IntAct=EBI-6658203, EBI-350517;
CC Q86YD7; Q99471: PFDN5; NbExp=3; IntAct=EBI-6658203, EBI-357275;
CC Q86YD7; Q9NRD5: PICK1; NbExp=3; IntAct=EBI-6658203, EBI-79165;
CC Q86YD7; Q9NWS0: PIH1D1; NbExp=5; IntAct=EBI-6658203, EBI-357318;
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CC Q86YD7; Q8WVV4-1: POF1B; NbExp=3; IntAct=EBI-6658203, EBI-11986735;
CC Q86YD7; Q96KQ4: PPP1R13B; NbExp=3; IntAct=EBI-6658203, EBI-1105153;
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CC Q86YD7; O43586: PSTPIP1; NbExp=6; IntAct=EBI-6658203, EBI-1050964;
CC Q86YD7; Q7L804: RAB11FIP2; NbExp=3; IntAct=EBI-6658203, EBI-1049676;
CC Q86YD7; Q15276: RABEP1; NbExp=3; IntAct=EBI-6658203, EBI-447043;
CC Q86YD7; Q5RL73: RBM48; NbExp=3; IntAct=EBI-6658203, EBI-473821;
CC Q86YD7; Q04864-2: REL; NbExp=3; IntAct=EBI-6658203, EBI-10829018;
CC Q86YD7; Q15669: RHOH; NbExp=3; IntAct=EBI-6658203, EBI-1244971;
CC Q86YD7; Q6NUQ1: RINT1; NbExp=3; IntAct=EBI-6658203, EBI-726876;
CC Q86YD7; Q9HAT0: ROPN1; NbExp=3; IntAct=EBI-6658203, EBI-1378139;
CC Q86YD7; Q96P16-3: RPRD1A; NbExp=3; IntAct=EBI-6658203, EBI-12840198;
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CC Q86YD7; Q8IUQ4: SIAH1; NbExp=3; IntAct=EBI-6658203, EBI-747107;
CC Q86YD7; P84022: SMAD3; NbExp=3; IntAct=EBI-6658203, EBI-347161;
CC Q86YD7; Q12824-2: SMARCB1; NbExp=3; IntAct=EBI-6658203, EBI-358436;
CC Q86YD7; Q13573: SNW1; NbExp=3; IntAct=EBI-6658203, EBI-632715;
CC Q86YD7; Q7Z699: SPRED1; NbExp=3; IntAct=EBI-6658203, EBI-5235340;
CC Q86YD7; Q96MF2: STAC3; NbExp=6; IntAct=EBI-6658203, EBI-745680;
CC Q86YD7; Q93045: STMN2; NbExp=3; IntAct=EBI-6658203, EBI-714194;
CC Q86YD7; O75558: STX11; NbExp=3; IntAct=EBI-6658203, EBI-714135;
CC Q86YD7; Q86VP1: TAX1BP1; NbExp=3; IntAct=EBI-6658203, EBI-529518;
CC Q86YD7; Q96N21: TEPSIN; NbExp=3; IntAct=EBI-6658203, EBI-11139477;
CC Q86YD7; Q9UBB9: TFIP11; NbExp=3; IntAct=EBI-6658203, EBI-1105213;
CC Q86YD7; Q08117-2: TLE5; NbExp=3; IntAct=EBI-6658203, EBI-11741437;
CC Q86YD7; Q12933: TRAF2; NbExp=6; IntAct=EBI-6658203, EBI-355744;
CC Q86YD7; Q96RU7: TRIB3; NbExp=3; IntAct=EBI-6658203, EBI-492476;
CC Q86YD7; P36406: TRIM23; NbExp=6; IntAct=EBI-6658203, EBI-740098;
CC Q86YD7; P14373: TRIM27; NbExp=3; IntAct=EBI-6658203, EBI-719493;
CC Q86YD7; Q8IWZ5: TRIM42; NbExp=3; IntAct=EBI-6658203, EBI-5235829;
CC Q86YD7; Q9BYV2: TRIM54; NbExp=3; IntAct=EBI-6658203, EBI-2130429;
CC Q86YD7; Q86WT6-2: TRIM69; NbExp=3; IntAct=EBI-6658203, EBI-11525489;
CC Q86YD7; Q9C026: TRIM9; NbExp=3; IntAct=EBI-6658203, EBI-720828;
CC Q86YD7; Q8N7C3: TRIML2; NbExp=3; IntAct=EBI-6658203, EBI-11059915;
CC Q86YD7; Q9H8Y1: VRTN; NbExp=3; IntAct=EBI-6658203, EBI-12894399;
CC Q86YD7; Q2TAL6: VWC2; NbExp=3; IntAct=EBI-6658203, EBI-11957238;
CC Q86YD7; O43829: ZBTB14; NbExp=3; IntAct=EBI-6658203, EBI-10176632;
CC Q86YD7; Q05516: ZBTB16; NbExp=3; IntAct=EBI-6658203, EBI-711925;
CC Q86YD7; O15156-2: ZBTB7B; NbExp=3; IntAct=EBI-6658203, EBI-11522250;
CC Q86YD7; Q96BR9: ZBTB8A; NbExp=3; IntAct=EBI-6658203, EBI-742740;
CC Q86YD7; Q53FD0-2: ZC2HC1C; NbExp=3; IntAct=EBI-6658203, EBI-14104088;
CC Q86YD7; Q9H0C1: ZMYND12; NbExp=3; IntAct=EBI-6658203, EBI-12030590;
CC Q86YD7; P52747: ZNF143; NbExp=3; IntAct=EBI-6658203, EBI-2849334;
CC Q86YD7; Q9UDV6: ZNF212; NbExp=8; IntAct=EBI-6658203, EBI-1640204;
CC Q86YD7; Q6P1L6: ZNF343; NbExp=3; IntAct=EBI-6658203, EBI-10252492;
CC Q86YD7; Q8TF50: ZNF526; NbExp=3; IntAct=EBI-6658203, EBI-11035148;
CC Q86YD7; Q9P0T4: ZNF581; NbExp=3; IntAct=EBI-6658203, EBI-745520;
CC Q86YD7; Q8N720: ZNF655; NbExp=3; IntAct=EBI-6658203, EBI-625509;
CC Q86YD7; P0C7X2: ZNF688; NbExp=3; IntAct=EBI-6658203, EBI-4395732;
CC Q86YD7; P36508: ZNF76; NbExp=3; IntAct=EBI-6658203, EBI-7254550;
CC Q86YD7; O95229: ZWINT; NbExp=3; IntAct=EBI-6658203, EBI-1001132;
CC -!- SIMILARITY: Belongs to the FAM90 family. {ECO:0000305}.
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DR EMBL; AK001270; BAA91593.1; -; mRNA.
DR EMBL; AC092111; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CH471116; EAW88629.1; -; Genomic_DNA.
DR EMBL; CH471116; EAW88630.1; -; Genomic_DNA.
DR EMBL; BC042608; AAH42608.1; -; mRNA.
DR CCDS; CCDS31738.1; -.
DR RefSeq; NP_001306911.1; NM_001319982.1.
DR RefSeq; NP_060558.3; NM_018088.3.
DR RefSeq; XP_011519021.1; XM_011520719.1.
DR RefSeq; XP_016875036.1; XM_017019547.1.
DR AlphaFoldDB; Q86YD7; -.
DR BioGRID; 120442; 179.
DR IntAct; Q86YD7; 203.
DR MINT; Q86YD7; -.
DR STRING; 9606.ENSP00000445418; -.
DR iPTMnet; Q86YD7; -.
DR PhosphoSitePlus; Q86YD7; -.
DR BioMuta; FAM90A1; -.
DR DMDM; 269849691; -.
DR PaxDb; Q86YD7; -.
DR PeptideAtlas; Q86YD7; -.
DR PRIDE; Q86YD7; -.
DR Antibodypedia; 23050; 33 antibodies from 10 providers.
DR DNASU; 55138; -.
DR Ensembl; ENST00000307435.10; ENSP00000307798.6; ENSG00000171847.11.
DR Ensembl; ENST00000538603.6; ENSP00000445418.1; ENSG00000171847.11.
DR GeneID; 55138; -.
DR KEGG; hsa:55138; -.
DR MANE-Select; ENST00000538603.6; ENSP00000445418.1; NM_018088.3; NP_060558.3.
DR UCSC; uc001quh.3; human.
DR CTD; 55138; -.
DR GeneCards; FAM90A1; -.
DR HGNC; HGNC:25526; FAM90A1.
DR HPA; ENSG00000171847; Low tissue specificity.
DR MIM; 613041; gene.
DR neXtProt; NX_Q86YD7; -.
DR OpenTargets; ENSG00000171847; -.
DR PharmGKB; PA142671796; -.
DR VEuPathDB; HostDB:ENSG00000171847; -.
DR eggNOG; ENOG502RU1C; Eukaryota.
DR GeneTree; ENSGT00910000144208; -.
DR HOGENOM; CLU_047915_0_1_1; -.
DR InParanoid; Q86YD7; -.
DR OMA; CDYLRVA; -.
DR OrthoDB; 791998at2759; -.
DR PhylomeDB; Q86YD7; -.
DR TreeFam; TF338572; -.
DR PathwayCommons; Q86YD7; -.
DR SignaLink; Q86YD7; -.
DR BioGRID-ORCS; 55138; 10 hits in 1062 CRISPR screens.
DR ChiTaRS; FAM90A1; human.
DR GenomeRNAi; 55138; -.
DR Pharos; Q86YD7; Tdark.
DR PRO; PR:Q86YD7; -.
DR Proteomes; UP000005640; Chromosome 12.
DR RNAct; Q86YD7; protein.
DR Bgee; ENSG00000171847; Expressed in cortical plate and 96 other tissues.
DR ExpressionAtlas; Q86YD7; baseline and differential.
DR Genevisible; Q86YD7; HS.
DR InterPro; IPR039213; FAM90.
DR InterPro; IPR041670; Znf-CCHC_6.
DR PANTHER; PTHR16035; PTHR16035; 1.
DR Pfam; PF15288; zf-CCHC_6; 1.
PE 1: Evidence at protein level;
KW Reference proteome.
FT CHAIN 1..464
FT /note="Protein FAM90A1"
FT /id="PRO_0000299592"
FT REGION 1..43
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 71..294
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 312..386
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 412..437
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 445..464
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 96..122
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 185..201
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 248..282
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 341..359
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VARIANT 123
FT /note="R -> G (in dbSNP:rs9738115)"
FT /evidence="ECO:0000269|PubMed:14702039,
FT ECO:0000269|PubMed:15489334"
FT /id="VAR_060293"
FT VARIANT 234
FT /note="A -> E (in dbSNP:rs9668582)"
FT /evidence="ECO:0000269|PubMed:15489334"
FT /id="VAR_057778"
FT VARIANT 334
FT /note="P -> L (in dbSNP:rs17855656)"
FT /evidence="ECO:0000269|PubMed:15489334"
FT /id="VAR_060294"
FT VARIANT 343
FT /note="R -> S (in dbSNP:rs9668475)"
FT /id="VAR_060154"
FT VARIANT 348
FT /note="T -> I (in dbSNP:rs9668474)"
FT /evidence="ECO:0000269|PubMed:14702039,
FT ECO:0000269|PubMed:15489334, ECO:0000269|Ref.3"
FT /id="VAR_060295"
FT VARIANT 410
FT /note="T -> A (in dbSNP:rs11044098)"
FT /id="VAR_060155"
FT CONFLICT 254..255
FT /note="VS -> AR (in Ref. 4; AAH42608)"
FT /evidence="ECO:0000305"
FT CONFLICT 344
FT /note="T -> TV (in Ref. 1; BAA91593)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 464 AA; 49793 MW; D9E36FCEE5021250 CRC64;
MMARRDPKPG AKRLVRAQTL QKQRRAPVGP RAPPPDEEDP RLKCKNCEAF GHTARSTRCP
MKCWKAALVP PNFGEKEGKE NLKPWKPQVE ANPGPLNKDK GEKEERPRPQ DPQRKALLHI
FSRKPPEKPL PNQKGSTESS DYLRVASGPM PVHTTSKRPR VDPVLSDRSA TEMSDRGSVL
ASLSPLRKAS LSSSSSLGPK ERQTGAAADI PQTAVRHQGP EPLLVVKPTH SSPAGGCREV
PQAASKTHGL LQAVSPQAQD KRPAVTSQPC PPAATHSLGL GSNLSFGPGA KRSAPAPIQA
CLNFPKKPRL GPFQIPESAI QGGELGAPEN LQPPPAATEL GPRTSPQTGT RTPAQVLSGD
RQPPHSRPCL PTAQACTMSH HPAASHDGAQ PLRVLFRRLE NGRWSSSLLT APSFHSPEKP
GAFLAQSPHV SEKSEGPCVR VPPSVLYEDL QVPSSSEDSD SDLE
