F90A2_HUMAN
ID F90A2_HUMAN Reviewed; 463 AA.
AC Q658T7;
DT 22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT 22-JUL-2008, sequence version 2.
DT 25-MAY-2022, entry version 72.
DE RecName: Full=Putative protein FAM90A2P;
GN Name=FAM90A2P;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16421571; DOI=10.1038/nature04406;
RA Nusbaum C., Mikkelsen T.S., Zody M.C., Asakawa S., Taudien S., Garber M.,
RA Kodira C.D., Schueler M.G., Shimizu A., Whittaker C.A., Chang J.L.,
RA Cuomo C.A., Dewar K., FitzGerald M.G., Yang X., Allen N.R., Anderson S.,
RA Asakawa T., Blechschmidt K., Bloom T., Borowsky M.L., Butler J., Cook A.,
RA Corum B., DeArellano K., DeCaprio D., Dooley K.T., Dorris L. III,
RA Engels R., Gloeckner G., Hafez N., Hagopian D.S., Hall J.L., Ishikawa S.K.,
RA Jaffe D.B., Kamat A., Kudoh J., Lehmann R., Lokitsang T., Macdonald P.,
RA Major J.E., Matthews C.D., Mauceli E., Menzel U., Mihalev A.H.,
RA Minoshima S., Murayama Y., Naylor J.W., Nicol R., Nguyen C., O'Leary S.B.,
RA O'Neill K., Parker S.C.J., Polley A., Raymond C.K., Reichwald K.,
RA Rodriguez J., Sasaki T., Schilhabel M., Siddiqui R., Smith C.L.,
RA Sneddon T.P., Talamas J.A., Tenzin P., Topham K., Venkataraman V., Wen G.,
RA Yamazaki S., Young S.K., Zeng Q., Zimmer A.R., Rosenthal A., Birren B.W.,
RA Platzer M., Shimizu N., Lander E.S.;
RT "DNA sequence and analysis of human chromosome 8.";
RL Nature 439:331-335(2006).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 21-463 (ISOFORM 2).
RC TISSUE=Stomach;
RX PubMed=17974005; DOI=10.1186/1471-2164-8-399;
RA Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U.,
RA Wellenreuther R., Mehrle A., Schuster C., Bahr A., Bloecker H., Heubner D.,
RA Hoerlein A., Michel G., Wedler H., Koehrer K., Ottenwaelder B., Poustka A.,
RA Wiemann S., Schupp I.;
RT "The full-ORF clone resource of the German cDNA consortium.";
RL BMC Genomics 8:399-399(2007).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q658T7-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q658T7-2; Sequence=VSP_034714;
CC -!- SIMILARITY: Belongs to the FAM90 family. {ECO:0000305}.
CC -!- CAUTION: Could be the product of a pseudogene. {ECO:0000305}.
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DR EMBL; AC145124; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AL832996; CAH56347.1; -; mRNA.
DR AlphaFoldDB; Q658T7; -.
DR GlyGen; Q658T7; 1 site, 1 O-linked glycan (1 site).
DR BioMuta; HGNC:32250; -.
DR DMDM; 206558319; -.
DR MassIVE; Q658T7; -.
DR PRIDE; Q658T7; -.
DR GeneCards; FAM90A2P; -.
DR HGNC; HGNC:32250; FAM90A2P.
DR neXtProt; NX_Q658T7; -.
DR InParanoid; Q658T7; -.
DR PhylomeDB; Q658T7; -.
DR Pharos; Q658T7; Tdark.
DR Proteomes; UP000005640; Unplaced.
DR RNAct; Q658T7; protein.
DR InterPro; IPR039213; FAM90.
DR InterPro; IPR041670; Znf-CCHC_6.
DR PANTHER; PTHR16035; PTHR16035; 1.
DR Pfam; PF15288; zf-CCHC_6; 1.
PE 5: Uncertain;
KW Alternative splicing; Reference proteome.
FT CHAIN 1..463
FT /note="Putative protein FAM90A2P"
FT /id="PRO_0000344035"
FT REGION 1..42
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 67..115
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 150..295
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 326..365
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 96..113
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 187..201
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 336..350
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 267..463
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:17974005"
FT /id="VSP_034714"
FT CONFLICT 156
FT /note="S -> C (in Ref. 2; CAH56347)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 463 AA; 50084 MW; AB19A8B161757A60 CRC64;
MTARRDPKPG AKRLVRAQTL QKQRRAPVGP RAPPPDEEDP RLKCKNCRAL GHTVRSTRCP
MKCWKAALVP PTLGKKEGKE NLKPWKPQVE ANPGPLNKDK GEKEERPRQQ DPQRKALLHI
FSGKPPEKLL PNRKGSTESS VFLRVASRPM PVHTTSKRPC VDPELADRSA TEMSGRGSVL
ASLSPLRKAS LRSSSSLGPK ERQTGAAADI PQPAVRHQGP EPLLVVKPTH SSREGGCREV
PQAASKTHGL LQAVRPQAQD KRPAVTQPGP PAATHSLGLG SNLSFRPGAK RPAQAPIQGC
LNFPKKPRLG PFQIPESAIQ GGELGALENL QPPPAATELG PSTSPQMGRR TPAQVPGVDR
QPPHSRPCLP TAQACTMSHH PAASHDGAQP LRVLFRRLEN RRWSSSLLAA PSFHSPEKLG
VFLAQSPHVS EKSEGPCVRV PPNVLYEDLQ VSSSSEDSDS DLQ