ID   F9_VACCP                Reviewed;         212 AA.
AC   P68453; P21018;
DT   23-NOV-2004, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   02-JUN-2021, entry version 43.
DE   RecName: Full=Protein F9;
GN   ORFNames=F9;
OS   Vaccinia virus (strain L-IVP) (VACV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus; Vaccinia virus.
OX   NCBI_TaxID=31531;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Mikryukov N.N., Chizhikov V.E., Prikhod'Ko G.G., Urmmanov I.M.,
RA   Serpinskii O.I., Blinov V.M., Nikulin A.E., Vasilenko S.K.;
RT   "Structural-functional organization of segment of vaccinia virus genome.";
RL   Biotekhnologiya 4:442-449(1988).
CC   -!- SUBUNIT: Interacts with G4; this interaction involves formation of a
CC       transient disulfide-bonded intermediate, allowing disulfide bond
CC       transfer. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Virion membrane {ECO:0000305}; Single-pass
CC       membrane protein {ECO:0000305}. Note=Component of the mature virion
CC       (MV) membrane. The mature virion is located in the cytoplasm of
CC       infected cells and is probably released by cell lysis (By similarity).
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the chordopoxvirinae L1 protein family.
CC       {ECO:0000305}.
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DR   EMBL; M57977; AAA48289.1; -; Genomic_DNA.
DR   RefSeq; YP_232930.1; NC_006998.1.
DR   SMR; P68453; -.
DR   TCDB; 1.G.11.1.1; the poxvirus cell entry protein complex (pep-c) family.
DR   DNASU; 3707505; -.
DR   GeneID; 3707505; -.
DR   KEGG; vg:3707505; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0019031; C:viral envelope; IEA:UniProtKB-KW.
DR   GO; GO:0055036; C:virion membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR003472; Virion_mem_poxvirus_L1.
DR   Pfam; PF02442; L1R_F9L; 1.
PE   3: Inferred from homology;
KW   Disulfide bond; Membrane; Transmembrane; Transmembrane helix;
KW   Viral envelope protein; Virion.
FT   CHAIN           1..212
FT                   /note="Protein F9"
FT                   /id="PRO_0000099492"
FT   TOPO_DOM        1..175
FT                   /note="Virion surface"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        176..196
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        197..212
FT                   /note="Intravirion"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   212 AA;  23792 MW;  5C99777A4CFADD9B CRC64;
     MAETKEFKTL YNLFIDSYLQ KLAQHSIPTN VTCAIHIGEV IGQFKNCALR ITNKCMSNSR
     LSFTLMVESF IEVISLLPEK DRRAIAEEIG IDLDDVPSAV SKLEKNCNAY AEVNNIIDIQ
     KLDIGECSAP PGQHMLLQIV NTGSAEANCG LQTIVKSLNK IYVPPIIENR LPYYDPWFLV
     GVAIILVIFT VAICSIRRNL ALKYRYGTFL YV