FA243_MOUSE
ID FA243_MOUSE Reviewed; 251 AA.
AC Q8CDS7;
DT 25-JAN-2012, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 03-AUG-2022, entry version 98.
DE RecName: Full=Uncharacterized protein C21orf140 homolog {ECO:0000305};
DE AltName: Full=Protein FAM243A {ECO:0000305};
GN Name=Fam243 {ECO:0000312|MGI:MGI:1922578};
GN Synonyms=Fam243a {ECO:0000250|UniProtKB:B9A014};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Testis;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J;
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.;
RL Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Testis;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- SIMILARITY: Belongs to the FAM243 family. {ECO:0000305}.
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DR EMBL; AK029653; BAC26550.1; -; mRNA.
DR EMBL; AC162305; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CH466602; EDL03788.1; -; Genomic_DNA.
DR EMBL; BC147584; AAI47585.1; -; mRNA.
DR EMBL; BC147622; AAI47623.1; -; mRNA.
DR CCDS; CCDS28335.1; -.
DR RefSeq; NP_083528.1; NM_029252.2.
DR AlphaFoldDB; Q8CDS7; -.
DR BioGRID; 217399; 2.
DR STRING; 10090.ENSMUSP00000049694; -.
DR PaxDb; Q8CDS7; -.
DR PRIDE; Q8CDS7; -.
DR DNASU; 75328; -.
DR Ensembl; ENSMUST00000062638; ENSMUSP00000049694; ENSMUSG00000051728.
DR GeneID; 75328; -.
DR KEGG; mmu:75328; -.
DR UCSC; uc007zyz.1; mouse.
DR CTD; 75328; -.
DR MGI; MGI:1922578; Fam243.
DR VEuPathDB; HostDB:ENSMUSG00000051728; -.
DR eggNOG; ENOG502RXAQ; Eukaryota.
DR GeneTree; ENSGT00390000010669; -.
DR HOGENOM; CLU_1106831_0_0_1; -.
DR InParanoid; Q8CDS7; -.
DR OMA; NKVRRWE; -.
DR OrthoDB; 969823at2759; -.
DR PhylomeDB; Q8CDS7; -.
DR TreeFam; TF335469; -.
DR BioGRID-ORCS; 75328; 3 hits in 72 CRISPR screens.
DR PRO; PR:Q8CDS7; -.
DR Proteomes; UP000000589; Chromosome 16.
DR RNAct; Q8CDS7; protein.
DR Bgee; ENSMUSG00000051728; Expressed in seminiferous tubule of testis and 11 other tissues.
DR Genevisible; Q8CDS7; MM.
DR InterPro; IPR037728; C21orf140-like.
DR PANTHER; PTHR35969; PTHR35969; 1.
PE 2: Evidence at transcript level;
KW Reference proteome.
FT CHAIN 1..251
FT /note="Uncharacterized protein C21orf140 homolog"
FT /id="PRO_0000415167"
SQ SEQUENCE 251 AA; 29348 MW; 795B98CE5804A6C1 CRC64;
MARFTNCLLK NIFTRSQFDS AKRRQCLQYL NALRSLQHNG YKTVYFGETE IPETLVTGED
FSDSYYIHTP SWCILHAGGS QGWVPWKYRM FLRNDLCIKK EDSLFLEFCD VVKRAYGKCA
IVVKGRRQQD EMKPKTDKEG EAKAYVPTSI NLTSIACSPG VAKSYGHELI SLPPYYNYLN
PLDSAWSSMK WFIINNRKEF CLQSVDNVYT YRYILFSDLI SKGIEKVNLT KWKAITNKVR
RWENYYLAKF S