ID   FA24A_HUMAN             Reviewed;         105 AA.
AC   A6NFZ4;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-JUL-2007, sequence version 1.
DT   03-AUG-2022, entry version 88.
DE   RecName: Full=Protein FAM24A;
DE   Flags: Precursor;
GN   Name=FAM24A;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15164054; DOI=10.1038/nature02462;
RA   Deloukas P., Earthrowl M.E., Grafham D.V., Rubenfield M., French L.,
RA   Steward C.A., Sims S.K., Jones M.C., Searle S., Scott C., Howe K.,
RA   Hunt S.E., Andrews T.D., Gilbert J.G.R., Swarbreck D., Ashurst J.L.,
RA   Taylor A., Battles J., Bird C.P., Ainscough R., Almeida J.P.,
RA   Ashwell R.I.S., Ambrose K.D., Babbage A.K., Bagguley C.L., Bailey J.,
RA   Banerjee R., Bates K., Beasley H., Bray-Allen S., Brown A.J., Brown J.Y.,
RA   Burford D.C., Burrill W., Burton J., Cahill P., Camire D., Carter N.P.,
RA   Chapman J.C., Clark S.Y., Clarke G., Clee C.M., Clegg S., Corby N.,
RA   Coulson A., Dhami P., Dutta I., Dunn M., Faulkner L., Frankish A.,
RA   Frankland J.A., Garner P., Garnett J., Gribble S., Griffiths C.,
RA   Grocock R., Gustafson E., Hammond S., Harley J.L., Hart E., Heath P.D.,
RA   Ho T.P., Hopkins B., Horne J., Howden P.J., Huckle E., Hynds C.,
RA   Johnson C., Johnson D., Kana A., Kay M., Kimberley A.M., Kershaw J.K.,
RA   Kokkinaki M., Laird G.K., Lawlor S., Lee H.M., Leongamornlert D.A.,
RA   Laird G., Lloyd C., Lloyd D.M., Loveland J., Lovell J., McLaren S.,
RA   McLay K.E., McMurray A., Mashreghi-Mohammadi M., Matthews L., Milne S.,
RA   Nickerson T., Nguyen M., Overton-Larty E., Palmer S.A., Pearce A.V.,
RA   Peck A.I., Pelan S., Phillimore B., Porter K., Rice C.M., Rogosin A.,
RA   Ross M.T., Sarafidou T., Sehra H.K., Shownkeen R., Skuce C.D., Smith M.,
RA   Standring L., Sycamore N., Tester J., Thorpe A., Torcasso W., Tracey A.,
RA   Tromans A., Tsolas J., Wall M., Walsh J., Wang H., Weinstock K., West A.P.,
RA   Willey D.L., Whitehead S.L., Wilming L., Wray P.W., Young L., Chen Y.,
RA   Lovering R.C., Moschonas N.K., Siebert R., Fechtel K., Bentley D.,
RA   Durbin R.M., Hubbard T., Doucette-Stamm L., Beck S., Smith D.R., Rogers J.;
RT   "The DNA sequence and comparative analysis of human chromosome 10.";
RL   Nature 429:375-381(2004).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the FAM24 family. {ECO:0000305}.
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DR   EMBL; AC073585; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   CCDS; CCDS31304.1; -.
DR   RefSeq; NP_001025059.1; NM_001029888.1.
DR   RefSeq; XP_016871127.1; XM_017015638.1.
DR   RefSeq; XP_016871128.1; XM_017015639.1.
DR   AlphaFoldDB; A6NFZ4; -.
DR   SMR; A6NFZ4; -.
DR   BioGRID; 125617; 1.
DR   STRING; 9606.ENSP00000357889; -.
DR   iPTMnet; A6NFZ4; -.
DR   PhosphoSitePlus; A6NFZ4; -.
DR   BioMuta; FAM24A; -.
DR   MassIVE; A6NFZ4; -.
DR   PaxDb; A6NFZ4; -.
DR   PeptideAtlas; A6NFZ4; -.
DR   PRIDE; A6NFZ4; -.
DR   ProteomicsDB; 1091; -.
DR   DNASU; 118670; -.
DR   Ensembl; ENST00000368894.2; ENSP00000357889.1; ENSG00000203795.3.
DR   GeneID; 118670; -.
DR   KEGG; hsa:118670; -.
DR   MANE-Select; ENST00000368894.2; ENSP00000357889.1; NM_001029888.3; NP_001025059.1.
DR   UCSC; uc001lgv.3; human.
DR   CTD; 118670; -.
DR   GeneCards; FAM24A; -.
DR   HGNC; HGNC:23470; FAM24A.
DR   HPA; ENSG00000203795; Tissue enriched (testis).
DR   neXtProt; NX_A6NFZ4; -.
DR   OpenTargets; ENSG00000203795; -.
DR   PharmGKB; PA134930660; -.
DR   VEuPathDB; HostDB:ENSG00000203795; -.
DR   eggNOG; ENOG502TEP5; Eukaryota.
DR   GeneTree; ENSGT00940000163005; -.
DR   HOGENOM; CLU_160106_0_0_1; -.
DR   InParanoid; A6NFZ4; -.
DR   OMA; CLYFKIA; -.
DR   OrthoDB; 1629398at2759; -.
DR   PhylomeDB; A6NFZ4; -.
DR   TreeFam; TF338384; -.
DR   SignaLink; A6NFZ4; -.
DR   BioGRID-ORCS; 118670; 4 hits in 1055 CRISPR screens.
DR   GenomeRNAi; 118670; -.
DR   Pharos; A6NFZ4; Tdark.
DR   PRO; PR:A6NFZ4; -.
DR   Proteomes; UP000005640; Chromosome 10.
DR   RNAct; A6NFZ4; protein.
DR   Bgee; ENSG00000203795; Expressed in sperm and 24 other tissues.
DR   Genevisible; A6NFZ4; HS.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   InterPro; IPR028122; FAM24.
DR   PANTHER; PTHR35860; PTHR35860; 1.
DR   Pfam; PF15193; FAM24; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Secreted; Signal.
FT   SIGNAL          1..32
FT                   /evidence="ECO:0000255"
FT   CHAIN           33..105
FT                   /note="Protein FAM24A"
FT                   /id="PRO_0000317244"
SQ   SEQUENCE   105 AA;  11258 MW;  F56ED2159E82B4B0 CRC64;
     MAKMFDLRTK IMIGIGSSLL VAAMVLLSVV FCLYFKVAKA LKAAKDPDAV AVKNHNPDKV
     CWATNSQAKA TTMESCPSLQ CCEGCRMHAS SDSLPPCCCD INEGL