FA24A_MOUSE
ID FA24A_MOUSE Reviewed; 98 AA.
AC Q8CF27;
DT 04-NOV-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 03-AUG-2022, entry version 103.
DE RecName: Full=Protein FAM24A;
DE Flags: Precursor;
GN Name=Fam24a;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Testis;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.;
RL Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Testis;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the FAM24 family. {ECO:0000305}.
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DR EMBL; AK006815; BAC25153.1; -; mRNA.
DR EMBL; CH466531; EDL17699.1; -; Genomic_DNA.
DR EMBL; CH466531; EDL17700.1; -; Genomic_DNA.
DR EMBL; BC048642; AAH48642.1; -; mRNA.
DR CCDS; CCDS40158.1; -.
DR RefSeq; NP_899095.1; NM_183272.2.
DR AlphaFoldDB; Q8CF27; -.
DR SMR; Q8CF27; -.
DR STRING; 10090.ENSMUSP00000081551; -.
DR PhosphoSitePlus; Q8CF27; -.
DR PaxDb; Q8CF27; -.
DR PRIDE; Q8CF27; -.
DR ProteomicsDB; 275735; -.
DR DNASU; 68223; -.
DR Ensembl; ENSMUST00000084505; ENSMUSP00000081551; ENSMUSG00000030859.
DR Ensembl; ENSMUST00000207439; ENSMUSP00000146929; ENSMUSG00000030859.
DR Ensembl; ENSMUST00000207784; ENSMUSP00000146579; ENSMUSG00000030859.
DR GeneID; 68223; -.
DR KEGG; mmu:68223; -.
DR UCSC; uc009kbe.1; mouse.
DR CTD; 118670; -.
DR MGI; MGI:1915473; Fam24a.
DR VEuPathDB; HostDB:ENSMUSG00000030859; -.
DR eggNOG; ENOG502TEP5; Eukaryota.
DR GeneTree; ENSGT00940000164044; -.
DR HOGENOM; CLU_160106_0_0_1; -.
DR InParanoid; Q8CF27; -.
DR OMA; CLYFKIA; -.
DR OrthoDB; 1629398at2759; -.
DR PhylomeDB; Q8CF27; -.
DR TreeFam; TF338384; -.
DR BioGRID-ORCS; 68223; 3 hits in 73 CRISPR screens.
DR PRO; PR:Q8CF27; -.
DR Proteomes; UP000000589; Chromosome 7.
DR RNAct; Q8CF27; protein.
DR Bgee; ENSMUSG00000030859; Expressed in spermatid and 33 other tissues.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR InterPro; IPR028122; FAM24.
DR PANTHER; PTHR35860; PTHR35860; 1.
DR Pfam; PF15193; FAM24; 1.
PE 3: Inferred from homology;
KW Reference proteome; Secreted; Signal.
FT SIGNAL 1..29
FT /evidence="ECO:0000255"
FT CHAIN 30..98
FT /note="Protein FAM24A"
FT /id="PRO_0000353116"
SQ SEQUENCE 98 AA; 10857 MW; 34F014B73018F91F CRC64;
MFDLRTKVMI GIASTLLIAA IMLITLVFCL YQKISKALKL AKEPECCIDP CKDPNEKIIR
AKPIIAETCR NLPCCDDCSI YKDVGSLPPC YCVTNEGL
