ID   FA30A_HUMAN             Reviewed;         134 AA.
AC   Q9NZY2; C9J8W9;
DT   05-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT   09-JAN-2013, sequence version 2.
DT   25-MAY-2022, entry version 83.
DE   RecName: Full=Putative uncharacterized protein FAM30A;
GN   Name=FAM30A {ECO:0000312|HGNC:HGNC:19955}; Synonyms=C14orf110, KIAA0125;
GN   ORFNames=HSPC053;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Blood;
RX   PubMed=11042152; DOI=10.1101/gr.140200;
RA   Zhang Q.-H., Ye M., Wu X.-Y., Ren S.-X., Zhao M., Zhao C.-J., Fu G.,
RA   Shen Y., Fan H.-Y., Lu G., Zhong M., Xu X.-R., Han Z.-G., Zhang J.-W.,
RA   Tao J., Huang Q.-H., Zhou J., Hu G.-X., Gu J., Chen S.-J., Chen Z.;
RT   "Cloning and functional analysis of cDNAs with open reading frames for 300
RT   previously undefined genes expressed in CD34+ hematopoietic stem/progenitor
RT   cells.";
RL   Genome Res. 10:1546-1560(2000).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12508121; DOI=10.1038/nature01348;
RA   Heilig R., Eckenberg R., Petit J.-L., Fonknechten N., Da Silva C.,
RA   Cattolico L., Levy M., Barbe V., De Berardinis V., Ureta-Vidal A.,
RA   Pelletier E., Vico V., Anthouard V., Rowen L., Madan A., Qin S., Sun H.,
RA   Du H., Pepin K., Artiguenave F., Robert C., Cruaud C., Bruels T.,
RA   Jaillon O., Friedlander L., Samson G., Brottier P., Cure S., Segurens B.,
RA   Aniere F., Samain S., Crespeau H., Abbasi N., Aiach N., Boscus D.,
RA   Dickhoff R., Dors M., Dubois I., Friedman C., Gouyvenoux M., James R.,
RA   Madan A., Mairey-Estrada B., Mangenot S., Martins N., Menard M., Oztas S.,
RA   Ratcliffe A., Shaffer T., Trask B., Vacherie B., Bellemere C., Belser C.,
RA   Besnard-Gonnet M., Bartol-Mavel D., Boutard M., Briez-Silla S.,
RA   Combette S., Dufosse-Laurent V., Ferron C., Lechaplais C., Louesse C.,
RA   Muselet D., Magdelenat G., Pateau E., Petit E., Sirvain-Trukniewicz P.,
RA   Trybou A., Vega-Czarny N., Bataille E., Bluet E., Bordelais I., Dubois M.,
RA   Dumont C., Guerin T., Haffray S., Hammadi R., Muanga J., Pellouin V.,
RA   Robert D., Wunderle E., Gauguet G., Roy A., Sainte-Marthe L., Verdier J.,
RA   Verdier-Discala C., Hillier L.W., Fulton L., McPherson J., Matsuda F.,
RA   Wilson R., Scarpelli C., Gyapay G., Wincker P., Saurin W., Quetier F.,
RA   Waterston R., Hood L., Weissenbach J.;
RT   "The DNA sequence and analysis of human chromosome 14.";
RL   Nature 421:601-607(2003).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M.,
RA   Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J.,
RA   Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S.,
RA   Turner R., Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H.,
RA   Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K.,
RA   Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D.,
RA   Hunkapiller M.W., Myers E.W., Venter J.C.;
RL   Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
RN   [4]
RP   INDUCTION.
RX   PubMed=19707560; DOI=10.1371/journal.pone.0006779;
RA   Uhrig M., Ittrich C., Wiedmann V., Knyazev Y., Weninger A.,
RA   Riemenschneider M., Hartmann T.;
RT   "New Alzheimer amyloid beta responsive genes identified in human
RT   neuroblastoma cells by hierarchical clustering.";
RL   PLoS ONE 4:E6779-E6779(2009).
CC   -!- INDUCTION: Down-regulated when the beta-APP42/beta-APP40 ratio is high,
CC       which is typical of Alzheimer's disease. {ECO:0000269|PubMed:19707560}.
CC   -!- CAUTION: Product of a dubious gene prediction. May be a non-coding RNA.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAF29025.1; Type=Frameshift; Evidence={ECO:0000305};
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DR   EMBL; AF161538; AAF29025.1; ALT_FRAME; mRNA.
DR   EMBL; AB019441; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CH471061; EAW81954.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q9NZY2; -.
DR   BioMuta; HGNC:19955; -.
DR   PRIDE; Q9NZY2; -.
DR   GeneCards; FAM30A; -.
DR   HGNC; HGNC:19955; FAM30A.
DR   MIM; 616623; gene.
DR   neXtProt; NX_Q9NZY2; -.
DR   InParanoid; Q9NZY2; -.
DR   ChiTaRS; FAM30A; human.
DR   Pharos; Q9NZY2; Tdark.
DR   PRO; PR:Q9NZY2; -.
DR   Proteomes; UP000005640; Unplaced.
DR   RNAct; Q9NZY2; protein.
PE   5: Uncertain;
KW   Reference proteome.
FT   CHAIN           1..134
FT                   /note="Putative uncharacterized protein FAM30A"
FT                   /id="PRO_0000089919"
FT   REGION          1..30
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        15..30
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   134 AA;  14626 MW;  E9A0D43429581614 CRC64;
     MGTLQGAALR SRERPSWPQE THGHRERTEE GCAVAAFSAD ALRTGGQELE QTGLRPKAGA
     PPMPDLLGHR ICTDIGKGWR MDGGRTCSCS SFCRCPERGA RRSSPDAPGL ALDFPLLLDL
     LWHLCSWTSQ PLEL