ID   FA321_LITFA             Reviewed;          14 AA.
AC   P86164;
DT   10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT   10-FEB-2009, sequence version 1.
DT   17-JUN-2020, entry version 5.
DE   RecName: Full=Fallaxidin-3.2.1;
OS   Litoria fallax (Eastern dwarf tree frog) (Hylomantis fallax).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Neobatrachia; Hyloidea; Hylidae; Pelodryadinae; Litoria.
OX   NCBI_TaxID=115422;
RN   [1] {ECO:0000305}
RP   PROTEIN SEQUENCE, FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, MASS
RP   SPECTROMETRY, AND AMIDATION AT LEU-14.
RC   TISSUE=Skin secretion {ECO:0000269|PubMed:18803332};
RX   PubMed=18803332; DOI=10.1002/rcm.3723;
RA   Jackway R.J., Bowie J.H., Bilusich D., Musgrave I.F., Surinya-Johnson K.H.,
RA   Tyler M.J., Eichinger P.C.H.;
RT   "The fallaxidin peptides from the skin secretion of the eastern dwarf tree
RT   frog Litoria fallax. Sequence determination by positive and negative ion
RT   electrospray mass spectrometry: antimicrobial activity and cDNA cloning of
RT   the fallaxidins.";
RL   Rapid Commun. Mass Spectrom. 22:3207-3216(2008).
CC   -!- FUNCTION: Lacks antibacterial activity against Gram-positive or Gram-
CC       negative bacteria. {ECO:0000269|PubMed:18803332}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:18803332}.
CC   -!- TISSUE SPECIFICITY: Expressed by the skin glands.
CC       {ECO:0000269|PubMed:18803332}.
CC   -!- MASS SPECTROMETRY: Mass=1510; Method=Electrospray;
CC       Evidence={ECO:0000269|PubMed:18803332};
CC   -!- SIMILARITY: Belongs to the frog skin active peptide (FSAP) family.
CC       Brevinin subfamily. {ECO:0000305}.
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DR   GO; GO:0005576; C:extracellular region; IDA:UniProtKB.
DR   GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Amidation; Amphibian defense peptide; Direct protein sequencing; Secreted.
FT   PEPTIDE         1..14
FT                   /note="Fallaxidin-3.2.1"
FT                   /id="PRO_0000361699"
FT   MOD_RES         14
FT                   /note="Leucine amide"
FT                   /evidence="ECO:0000269|PubMed:18803332"
SQ   SEQUENCE   14 AA;  1512 MW;  D213D2EE5A520C42 CRC64;
     LDFAKHVIGI ASKL