FA43A_MOUSE
ID FA43A_MOUSE Reviewed; 424 AA.
AC Q8BUP8; A4FTY9; Q8R231;
DT 16-AUG-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 03-AUG-2022, entry version 116.
DE RecName: Full=Protein FAM43A;
GN Name=Fam43a;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Spinal cord;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=CD-1, and FVB/N; TISSUE=Brain, Neural stem cell, and Salivary gland;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- SIMILARITY: Belongs to the FAM43 family. {ECO:0000305}.
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DR EMBL; AK083036; BAC38739.1; -; mRNA.
DR EMBL; BC022623; AAH22623.1; -; mRNA.
DR EMBL; BC099947; AAH99947.1; -; mRNA.
DR EMBL; BC138882; AAI38883.1; -; mRNA.
DR EMBL; BC138884; AAI38885.1; -; mRNA.
DR CCDS; CCDS28103.1; -.
DR RefSeq; NP_808300.1; NM_177632.3.
DR AlphaFoldDB; Q8BUP8; -.
DR SMR; Q8BUP8; -.
DR STRING; 10090.ENSMUSP00000056555; -.
DR PhosphoSitePlus; Q8BUP8; -.
DR MaxQB; Q8BUP8; -.
DR PaxDb; Q8BUP8; -.
DR PRIDE; Q8BUP8; -.
DR ProteomicsDB; 266822; -.
DR Antibodypedia; 68591; 36 antibodies from 10 providers.
DR DNASU; 224093; -.
DR Ensembl; ENSMUST00000059078; ENSMUSP00000056555; ENSMUSG00000046546.
DR GeneID; 224093; -.
DR KEGG; mmu:224093; -.
DR UCSC; uc007ywy.2; mouse.
DR CTD; 131583; -.
DR MGI; MGI:2676309; Fam43a.
DR VEuPathDB; HostDB:ENSMUSG00000046546; -.
DR eggNOG; KOG4448; Eukaryota.
DR GeneTree; ENSGT00940000161593; -.
DR HOGENOM; CLU_056673_2_0_1; -.
DR InParanoid; Q8BUP8; -.
DR OMA; AMHLECG; -.
DR OrthoDB; 1201276at2759; -.
DR PhylomeDB; Q8BUP8; -.
DR TreeFam; TF314159; -.
DR BioGRID-ORCS; 224093; 1 hit in 72 CRISPR screens.
DR ChiTaRS; Fam43a; mouse.
DR PRO; PR:Q8BUP8; -.
DR Proteomes; UP000000589; Chromosome 16.
DR RNAct; Q8BUP8; protein.
DR Bgee; ENSMUSG00000046546; Expressed in vestibular membrane of cochlear duct and 202 other tissues.
DR Genevisible; Q8BUP8; MM.
DR CDD; cd01214; PTB_FAM43A; 1.
DR Gene3D; 2.30.29.30; -; 1.
DR InterPro; IPR033930; FAM43A/B_PTB.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR006020; PTB/PI_dom.
DR Pfam; PF14719; PID_2; 1.
DR SMART; SM00462; PTB; 1.
PE 2: Evidence at transcript level;
KW Reference proteome.
FT CHAIN 1..424
FT /note="Protein FAM43A"
FT /id="PRO_0000187025"
FT REGION 261..299
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 382..424
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 261..293
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 408..424
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 424 AA; 46206 MW; AC7C4F9B751365C0 CRC64;
MLPWKKHKFE LLAEAPPRQA SKPKGYAVSL HYSALSSLAR ACPEGALSRV GSMFRSKRKK
LHITSEDPTY TVLYLGNATT IQARGDGCTD LAVGKIWSKS EAGRQGTKMK LTVSAQGIRM
VHAEERALRR PGHLYLLHRV TYCVADARLP KVFAWVYRHE LKHKAVMLRC HAVLVSKPEK
AQAMALLLYQ TSANALAEFK RLKRRDDARH QQQELVGAHT IPLVPLRKLL LHGPCCYKPP
VERSRSAPKL GSITEDLLGE QQEEELQEEE EEHLEDCLEE EEEEDGVGDG DPAEEEAEAQ
RALVVAMQLE CEDLLDPLEN GHEEALGDGG VSLGPSSGTS LPLSVCASDM KAQLSQLISD
LGDLSFGNDV STLETDLRVT RLLSGESTGS ESSIEGGGLD ATPVSPGNPS GPADSTSLDE
PYSG
