ID   FA72A_BOVIN             Reviewed;         149 AA.
AC   A6QL50;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   21-AUG-2007, sequence version 1.
DT   03-AUG-2022, entry version 61.
DE   RecName: Full=Protein FAM72A;
GN   Name=FAM72A;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Ascending colon;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May play a role in the regulation of cellular reactive oxygen
CC       species metabolism. May participate in cell growth regulation (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with UNG. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Mitochondrion
CC       {ECO:0000250}.
CC   -!- TISSUE SPECIFICITY: Expressed at high levels in stomach and also in
CC       kidney and, at low levels, in heart (at protein level). In the stomach,
CC       highly expressed in foveolar cells, parietal cells and chief cells (at
CC       protein level). In kidney, expressed in endothelial cells, mesangial
CC       and epithelial cells (parietal and visceral epithelium) around
CC       glomerulus (at protein level).
CC   -!- SIMILARITY: Belongs to the FAM72 family. {ECO:0000305}.
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DR   EMBL; BC146229; AAI46230.1; -; mRNA.
DR   RefSeq; NP_001094733.1; NM_001101263.1.
DR   AlphaFoldDB; A6QL50; -.
DR   STRING; 9913.ENSBTAP00000026937; -.
DR   PaxDb; A6QL50; -.
DR   Ensembl; ENSBTAT00000026937; ENSBTAP00000026937; ENSBTAG00000020227.
DR   GeneID; 616965; -.
DR   KEGG; bta:616965; -.
DR   CTD; 729533; -.
DR   VEuPathDB; HostDB:ENSBTAG00000020227; -.
DR   eggNOG; ENOG502S1HA; Eukaryota.
DR   GeneTree; ENSGT00390000005106; -.
DR   HOGENOM; CLU_127817_0_0_1; -.
DR   InParanoid; A6QL50; -.
DR   OMA; DICKCKL; -.
DR   OrthoDB; 1574121at2759; -.
DR   TreeFam; TF329231; -.
DR   Proteomes; UP000009136; Chromosome 16.
DR   Bgee; ENSBTAG00000020227; Expressed in oocyte and 64 other tissues.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR   InterPro; IPR026768; FAM72.
DR   PANTHER; PTHR31841; PTHR31841; 1.
DR   Pfam; PF14976; FAM72; 1.
PE   1: Evidence at protein level;
KW   Cytoplasm; Mitochondrion; Reference proteome.
FT   CHAIN           1..149
FT                   /note="Protein FAM72A"
FT                   /id="PRO_0000340255"
SQ   SEQUENCE   149 AA;  16684 MW;  4AD00CEF6DD15B80 CRC64;
     MSTSSCSFKD RRVSILCCKF CKQVLSSRGM KAVLLADTEI DLFSTDIPPT NAVDFIGRCY
     FTEICKCKLK DIACLKCGNI VGYHVIVPCC SCLLSCNNGH FWMFHSQAVY GINRLDSTGV
     NFLLWGNLPE VEENTDEDML DISAEECIR