ID   FA72C_HUMAN             Reviewed;         149 AA.
AC   H0Y354;
DT   13-NOV-2013, integrated into UniProtKB/Swiss-Prot.
DT   13-NOV-2013, sequence version 2.
DT   03-AUG-2022, entry version 62.
DE   RecName: Full=Protein FAM72C;
GN   Name=FAM72C;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16710414; DOI=10.1038/nature04727;
RA   Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A.,
RA   Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A., Jones M.C., Gillson C.,
RA   Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K.,
RA   Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C.,
RA   Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W.,
RA   Ashwell R.I.S., Aubin K., Babbage A.K., Bagguley C.L., Bailey J.,
RA   Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J.,
RA   Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y.,
RA   Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J.,
RA   Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H.,
RA   Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L.,
RA   Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J.,
RA   Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S.,
RA   Harrison E.S.I., Hart E., Haugen E., Heath P.D., Holmes S., Holt K.,
RA   Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R.,
RA   Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M.,
RA   Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S.,
RA   Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J.,
RA   Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W.,
RA   McLaren S., Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N.,
RA   Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V.,
RA   Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J.,
RA   Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E.,
RA   Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S.,
RA   Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M.,
RA   White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H.,
RA   Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E.,
RA   Durbin R.M., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G.,
RA   Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R.;
RT   "The DNA sequence and biological annotation of human chromosome 1.";
RL   Nature 441:315-321(2006).
CC   -!- SIMILARITY: Belongs to the FAM72 family. {ECO:0000305}.
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DR   EMBL; AC246680; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   CCDS; CCDS72850.1; -.
DR   RefSeq; NP_001274314.1; NM_001287385.1.
DR   AlphaFoldDB; H0Y354; -.
DR   STRING; 9606.ENSP00000463032; -.
DR   iPTMnet; H0Y354; -.
DR   PhosphoSitePlus; H0Y354; -.
DR   BioMuta; FAM72C; -.
DR   PeptideAtlas; H0Y354; -.
DR   PRIDE; H0Y354; -.
DR   Ensembl; ENST00000584486.6; ENSP00000463032.1; ENSG00000263513.6.
DR   GeneID; 554282; -.
DR   KEGG; hsa:554282; -.
DR   MANE-Select; ENST00000584486.6; ENSP00000463032.1; NM_001287385.2; NP_001274314.1.
DR   UCSC; uc031uqs.2; human.
DR   CTD; 554282; -.
DR   GeneCards; FAM72C; -.
DR   HGNC; HGNC:30602; FAM72C.
DR   HPA; ENSG00000263513; Tissue enhanced (bone marrow, lymphoid tissue).
DR   neXtProt; NX_H0Y354; -.
DR   OpenTargets; ENSG00000263513; -.
DR   VEuPathDB; HostDB:ENSG00000263513; -.
DR   eggNOG; ENOG502S1HA; Eukaryota.
DR   GeneTree; ENSGT00390000005106; -.
DR   HOGENOM; CLU_127817_0_0_1; -.
DR   InParanoid; H0Y354; -.
DR   OMA; HATAYMS; -.
DR   OrthoDB; 1574121at2759; -.
DR   PhylomeDB; H0Y354; -.
DR   PathwayCommons; H0Y354; -.
DR   BioGRID-ORCS; 554282; 8 hits in 146 CRISPR screens.
DR   GenomeRNAi; 554282; -.
DR   Pharos; H0Y354; Tdark.
DR   PRO; PR:H0Y354; -.
DR   Proteomes; UP000005640; Chromosome 1.
DR   RNAct; H0Y354; protein.
DR   Bgee; ENSG00000263513; Expressed in lymph node and 87 other tissues.
DR   ExpressionAtlas; H0Y354; baseline and differential.
DR   Genevisible; H0Y354; HS.
DR   GO; GO:0005829; C:cytosol; IDA:HPA.
DR   GO; GO:0043231; C:intracellular membrane-bounded organelle; IDA:HPA.
DR   InterPro; IPR026768; FAM72.
DR   PANTHER; PTHR31841; PTHR31841; 1.
DR   Pfam; PF14976; FAM72; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..149
FT                   /note="Protein FAM72C"
FT                   /id="PRO_0000424443"
SQ   SEQUENCE   149 AA;  16730 MW;  1B05FE38B7473411 CRC64;
     MSTNICSFKD RCVSILCCKF CKQVLSSRGM KAVLLADTEI DLFSTDIPPT NAVDFTGRCY
     FTKICKCKLK DIACLKCGNI VVYHVIVPCS SCLLSCNNRH FWMFHSQAVY DINRLDSTGV
     NVLLRGNLPE IEESTDEDVL NISAEECIR