ID   FA76B_DANRE             Reviewed;         328 AA.
AC   Q6PBM7;
DT   11-JUL-2006, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 84.
DE   RecName: Full=Protein FAM76B;
GN   Name=fam76b; ORFNames=zgc:73333;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Eye;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-188, AND IDENTIFICATION BY
RP   MASS SPECTROMETRY.
RC   TISSUE=Embryo;
RX   PubMed=18307296; DOI=10.1021/pr700667w;
RA   Lemeer S., Pinkse M.W.H., Mohammed S., van Breukelen B., den Hertog J.,
RA   Slijper M., Heck A.J.R.;
RT   "Online automated in vivo zebrafish phosphoproteomics: from large-scale
RT   analysis down to a single embryo.";
RL   J. Proteome Res. 7:1555-1564(2008).
CC   -!- SIMILARITY: Belongs to the FAM76 family. {ECO:0000305}.
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DR   EMBL; BC059652; AAH59652.1; -; mRNA.
DR   RefSeq; NP_956226.1; NM_199932.1.
DR   AlphaFoldDB; Q6PBM7; -.
DR   SMR; Q6PBM7; -.
DR   BioGRID; 85516; 1.
DR   STRING; 7955.ENSDARP00000026447; -.
DR   iPTMnet; Q6PBM7; -.
DR   PaxDb; Q6PBM7; -.
DR   PRIDE; Q6PBM7; -.
DR   Ensembl; ENSDART00000024815; ENSDARP00000026447; ENSDARG00000012432.
DR   GeneID; 335015; -.
DR   KEGG; dre:335015; -.
DR   CTD; 143684; -.
DR   ZFIN; ZDB-GENE-030131-6955; fam76b.
DR   eggNOG; KOG3990; Eukaryota.
DR   GeneTree; ENSGT00940000159074; -.
DR   HOGENOM; CLU_029220_1_0_1; -.
DR   InParanoid; Q6PBM7; -.
DR   OMA; KECRGAF; -.
DR   OrthoDB; 1061935at2759; -.
DR   PhylomeDB; Q6PBM7; -.
DR   TreeFam; TF313644; -.
DR   PRO; PR:Q6PBM7; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 5.
DR   Bgee; ENSDARG00000012432; Expressed in mature ovarian follicle and 26 other tissues.
DR   GO; GO:0016607; C:nuclear speck; ISS:UniProtKB.
DR   InterPro; IPR032017; FAM76.
DR   InterPro; IPR029661; FAM76B.
DR   PANTHER; PTHR46176; PTHR46176; 1.
DR   PANTHER; PTHR46176:SF3; PTHR46176:SF3; 1.
DR   Pfam; PF16046; FAM76; 1.
PE   1: Evidence at protein level;
KW   Coiled coil; Phosphoprotein; Reference proteome.
FT   CHAIN           1..328
FT                   /note="Protein FAM76B"
FT                   /id="PRO_0000245765"
FT   REGION          143..232
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          237..316
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        164..181
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        182..200
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        215..232
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         188
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000269|PubMed:18307296"
SQ   SEQUENCE   328 AA;  37691 MW;  A140CCB78F793F96 CRC64;
     MATSALYACT KCNQRFPFEE LSQGQQLCKE CRIAHPIVKC TYCRSEFQQE SKTNTICKKC
     AQNVKQFGTP KPCQYCNIIA AFIGTKCQRC TNSEKKYGPP QTCEQCKQQC AFDRKDEGRR
     KVDGKLLCWL CTLSYRRVLQ KTKEQRKGLG SSHSNSSSLS EKEHQRHHHH HQHHRHGSSH
     HKISGNLSPE QDQGLWKQSI QKETPKKKPK LETKPSNGDS SSITQSMDSG GTDNFILISQ
     LKEEVMSLKR MLQQRDQTIL EKDRKLTELK ADFQYQESNM RVKMNNMEKA HKEAMEQQQA
     KNRELLKQVA ALSKGKKFDR SGSSLLLP