FA78A_MOUSE
ID FA78A_MOUSE Reviewed; 283 AA.
AC Q8C552;
DT 12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 03-AUG-2022, entry version 116.
DE RecName: Full=Protein FAM78A;
GN Name=Fam78a;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Spleen, and Thymus;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Testis;
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
CC -!- SIMILARITY: Belongs to the FAM78 family. {ECO:0000305}.
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DR EMBL; AK079514; BAC37667.1; -; mRNA.
DR EMBL; AK165375; BAE38152.1; -; mRNA.
DR CCDS; CCDS15905.1; -.
DR RefSeq; NP_780720.1; NM_175511.4.
DR RefSeq; XP_011237398.1; XM_011239096.2.
DR RefSeq; XP_011237400.1; XM_011239098.2.
DR RefSeq; XP_011237401.1; XM_011239099.1.
DR RefSeq; XP_011237402.1; XM_011239100.2.
DR AlphaFoldDB; Q8C552; -.
DR STRING; 10090.ENSMUSP00000052826; -.
DR PhosphoSitePlus; Q8C552; -.
DR SwissPalm; Q8C552; -.
DR EPD; Q8C552; -.
DR MaxQB; Q8C552; -.
DR PaxDb; Q8C552; -.
DR PRIDE; Q8C552; -.
DR ProteomicsDB; 271848; -.
DR Antibodypedia; 18087; 120 antibodies from 19 providers.
DR Ensembl; ENSMUST00000056406; ENSMUSP00000052826; ENSMUSG00000050592.
DR Ensembl; ENSMUST00000139629; ENSMUSP00000115010; ENSMUSG00000050592.
DR GeneID; 241303; -.
DR KEGG; mmu:241303; -.
DR UCSC; uc008jek.1; mouse.
DR CTD; 286336; -.
DR MGI; MGI:2443569; Fam78a.
DR VEuPathDB; HostDB:ENSMUSG00000050592; -.
DR eggNOG; ENOG502QPXK; Eukaryota.
DR GeneTree; ENSGT00390000018059; -.
DR HOGENOM; CLU_085745_0_0_1; -.
DR InParanoid; Q8C552; -.
DR OMA; YGDQGMS; -.
DR OrthoDB; 958650at2759; -.
DR PhylomeDB; Q8C552; -.
DR TreeFam; TF329533; -.
DR BioGRID-ORCS; 241303; 1 hit in 72 CRISPR screens.
DR ChiTaRS; Fam78a; mouse.
DR PRO; PR:Q8C552; -.
DR Proteomes; UP000000589; Chromosome 2.
DR RNAct; Q8C552; protein.
DR Bgee; ENSMUSG00000050592; Expressed in interventricular septum and 146 other tissues.
DR ExpressionAtlas; Q8C552; baseline and differential.
DR Genevisible; Q8C552; MM.
DR InterPro; IPR029638; FAM78.
DR InterPro; IPR029640; FAM78A.
DR PANTHER; PTHR31655; PTHR31655; 1.
DR PANTHER; PTHR31655:SF3; PTHR31655:SF3; 1.
PE 1: Evidence at protein level;
KW Reference proteome.
FT CHAIN 1..283
FT /note="Protein FAM78A"
FT /id="PRO_0000265113"
SQ SEQUENCE 283 AA; 32068 MW; 8CD883048C98C402 CRC64;
MPCYFWDCWP SLEIRAVLCA MGCIQSIGGK ARVFREGITV IDVKASIDPI PTSIDESSSV
VLRYRTPHFR ASAQVVMPPI PKKETWIVGW IQACSHMEFY NQYGEQGMSS WELPDLQEGK
IEAISDSDGV NYPWYGNTTE TCTIVGPTKR DSKFIISMND NFYPSVTWAV PVSESNVAKL
TNIYRDQSFT TWLVATNTST NDMIILQTLH WRMQLSIEVN PNRPLGQRAR LREPIAQDQP
KILSKNEPIP PSALVKPNAN DAQVLMWRPK YGQPLVVIPP KHR