ID   FA83A_XENLA             Reviewed;         443 AA.
AC   Q6PF42;
DT   15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 48.
DE   RecName: Full=Protein FAM83A {ECO:0000305};
GN   Name=fam83a {ECO:0000250|UniProtKB:Q86UY5};
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (SEP-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May function in the epidermal growth factor receptor/EGFR
CC       signaling pathway. {ECO:0000250|UniProtKB:Q86UY5}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q86UY5}.
CC   -!- SIMILARITY: Belongs to the FAM83 family. {ECO:0000305}.
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DR   EMBL; BC057736; AAH57736.1; -; mRNA.
DR   RefSeq; NP_001079963.1; NM_001086494.1.
DR   AlphaFoldDB; Q6PF42; -.
DR   SMR; Q6PF42; -.
DR   PRIDE; Q6PF42; -.
DR   DNASU; 379654; -.
DR   GeneID; 379654; -.
DR   KEGG; xla:379654; -.
DR   CTD; 379654; -.
DR   Xenbase; XB-GENE-947624; fam83a.L.
DR   OMA; YSFSWLC; -.
DR   OrthoDB; 550760at2759; -.
DR   Proteomes; UP000186698; Chromosome 6L.
DR   Bgee; 379654; Expressed in zone of skin and 9 other tissues.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0008283; P:cell population proliferation; ISS:UniProtKB.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; ISS:UniProtKB.
DR   InterPro; IPR012461; FAM83_N.
DR   Pfam; PF07894; FAM83; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..443
FT                   /note="Protein FAM83A"
FT                   /id="PRO_0000286815"
FT   REGION          311..403
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        314..352
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        366..403
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   443 AA;  50473 MW;  0C0D93BC0C6859EC CRC64;
     MNRSKTFGKI RKRLEEAKNK WARLCKVEYS YNESARLATD ALLDGGVEDY EKVLNEEGEV
     DFLSGDEIQY IMKNIKEPMY SNDNQTEGEC GSAANGNKSE CFYPMNSDKS EPVSTLHNWS
     AEEKPYLKDK SSATVYFQTD KTNNVRETIR RCIHRTTQVL AILMDEFTDA EIFCDVLEAA
     NKRNIFVYLL LDANKLHLFT QMCEKLQVRD LHMKNISVRS VTGDVYCAKS GKKFAGQIHE
     KFIISDWRCV LSGSYSFTWL SGQVHRNFLY KFSGVVVELF DEEFRHLYGS SKPVMGLKSP
     APMAPVLRRE DSGVSVMTDS TPESVNTTSE PFSSTSTASI SNDSQRPKSP ESTDPVLASP
     PRSPVRSPLQ RMNSLHGYPS LISPPPQSNY QPNYYQRNYA PDSPSSFFNN NANIYRSFRM
     RQDDFSTPRF NQGWSLFSRS TMT