ID   FA83A_XENTR             Reviewed;         441 AA.
AC   Q66JF7;
DT   15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   03-AUG-2022, entry version 65.
DE   RecName: Full=Protein FAM83A {ECO:0000305};
GN   Name=fam83a {ECO:0000250|UniProtKB:Q86UY5};
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (AUG-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May function in the epidermal growth factor receptor/EGFR
CC       signaling pathway. {ECO:0000250|UniProtKB:Q86UY5}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q86UY5}.
CC   -!- SIMILARITY: Belongs to the FAM83 family. {ECO:0000305}.
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DR   EMBL; BC080932; AAH80932.1; -; mRNA.
DR   RefSeq; NP_001008047.1; NM_001008046.1.
DR   AlphaFoldDB; Q66JF7; -.
DR   SMR; Q66JF7; -.
DR   PaxDb; Q66JF7; -.
DR   DNASU; 493409; -.
DR   Ensembl; ENSXETT00000050140; ENSXETP00000050140; ENSXETG00000023191.
DR   GeneID; 493409; -.
DR   KEGG; xtr:493409; -.
DR   CTD; 84985; -.
DR   Xenbase; XB-GENE-947619; fam83a.
DR   eggNOG; ENOG502QQDU; Eukaryota.
DR   InParanoid; Q66JF7; -.
DR   OrthoDB; 550760at2759; -.
DR   Proteomes; UP000008143; Chromosome 6.
DR   Proteomes; UP000790000; Unplaced.
DR   Bgee; ENSXETG00000023191; Expressed in skin of body and 4 other tissues.
DR   ExpressionAtlas; Q66JF7; differential.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0019901; F:protein kinase binding; IBA:GO_Central.
DR   GO; GO:0008283; P:cell population proliferation; ISS:UniProtKB.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IBA:GO_Central.
DR   InterPro; IPR012461; FAM83_N.
DR   Pfam; PF07894; FAM83; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..441
FT                   /note="Protein FAM83A"
FT                   /id="PRO_0000286816"
FT   REGION          81..108
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          312..368
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        313..350
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   441 AA;  50081 MW;  CC7E708328F063DD CRC64;
     MNKSKTFGKI KKRIEEAKNK WARLSKADYS YNESARLATD ALLDGGVEDY QKVLSEEGEV
     DLLSGDELQY ILKNIKAPLY SNDNQTEGEN GSAANGNKSE SYYPMNSDSE PVPTLHNWSA
     EEKPYLKDKS SATVYFQADK TNNVRETIRR CINKTTQALA ILMDEFTDAE IFCDVLEAAN
     KRNIFVYLLL DANKLHLFIQ MCEKLQVRDL HMTNISVRSV TGDVYCAKSG KKFAGQINEK
     FIISDWRFVL SGTYSFTWLS GQVHRNFLYK FSGDVVELFD EEFRNLYASS KPVMGLKSPA
     PMAPVLRRED SGMSIMSDSN PESINTTSEP FSSISTASIS NDSQRPKSPV STTPVPSPPS
     SPVKSPLQRV NSFHGYSSLI SPPPQINYQS NYYQRNYAPD PPSFFYNNNA NFYRSFRMRQ
     EDFSMPRFNQ GWRLFSRATM T