FA89A_MOUSE
ID FA89A_MOUSE Reviewed; 175 AA.
AC Q14BJ1; Q8R3X3;
DT 20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT 20-JAN-2009, sequence version 2.
DT 03-AUG-2022, entry version 81.
DE RecName: Full=Protein FAM89A;
GN Name=Fam89a;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J;
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2), AND NUCLEOTIDE SEQUENCE
RP [LARGE SCALE MRNA] OF 54-175 (ISOFORM 1).
RC STRAIN=FVB/N-3; TISSUE=Mammary tumor;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q14BJ1-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q14BJ1-2; Sequence=VSP_036132;
CC -!- SIMILARITY: Belongs to the FAM89 family. {ECO:0000305}.
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DR EMBL; AC151736; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC023460; AAH23460.1; -; mRNA.
DR EMBL; BC115734; AAI15735.1; -; mRNA.
DR EMBL; BC115819; AAI15820.1; -; mRNA.
DR CCDS; CCDS40516.1; -. [Q14BJ1-1]
DR RefSeq; NP_001074589.1; NM_001081120.1. [Q14BJ1-1]
DR AlphaFoldDB; Q14BJ1; -.
DR SMR; Q14BJ1; -.
DR STRING; 10090.ENSMUSP00000058156; -.
DR PhosphoSitePlus; Q14BJ1; -.
DR PaxDb; Q14BJ1; -.
DR PRIDE; Q14BJ1; -.
DR ProteomicsDB; 271542; -. [Q14BJ1-1]
DR Antibodypedia; 68454; 8 antibodies from 4 providers.
DR Ensembl; ENSMUST00000055257; ENSMUSP00000058156; ENSMUSG00000043068. [Q14BJ1-1]
DR GeneID; 69627; -.
DR KEGG; mmu:69627; -.
DR UCSC; uc009nxp.1; mouse. [Q14BJ1-1]
DR CTD; 375061; -.
DR MGI; MGI:1916877; Fam89a.
DR VEuPathDB; HostDB:ENSMUSG00000043068; -.
DR eggNOG; ENOG502S28T; Eukaryota.
DR GeneTree; ENSGT00940000153370; -.
DR HOGENOM; CLU_128818_1_0_1; -.
DR InParanoid; Q14BJ1; -.
DR OMA; MMENGFF; -.
DR OrthoDB; 1585340at2759; -.
DR PhylomeDB; Q14BJ1; -.
DR BioGRID-ORCS; 69627; 1 hit in 74 CRISPR screens.
DR ChiTaRS; Fam89a; mouse.
DR PRO; PR:Q14BJ1; -.
DR Proteomes; UP000000589; Chromosome 8.
DR RNAct; Q14BJ1; protein.
DR Bgee; ENSMUSG00000043068; Expressed in lumbar dorsal root ganglion and 95 other tissues.
DR Genevisible; Q14BJ1; MM.
PE 2: Evidence at transcript level;
KW Alternative splicing; Reference proteome.
FT CHAIN 1..175
FT /note="Protein FAM89A"
FT /id="PRO_0000358921"
FT REGION 141..175
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 147..175
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 1..71
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:15489334"
FT /id="VSP_036132"
SQ SEQUENCE 175 AA; 18690 MW; B99C9BEA650A5ACA CRC64;
MSGTGSAGMA RGLRVDGLPP LPKSLSGLLH SAAGGAAGGW RHLERLYAQK SRIQDELNRG
GAGGGGARAA GMRTKPPNLD AALALLRKEM VGLRQLDMSL LCQLYSLYES IQEYKGACQA
ASSLDCTYAL ENGFFDDEED FQEQGSLQDG QHHGSPRDQS PLTHLSSSDW ILESI
