3MGH_CLOBM
ID 3MGH_CLOBM Reviewed; 203 AA.
AC B1KZY0;
DT 14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT 29-APR-2008, sequence version 1.
DT 25-MAY-2022, entry version 64.
DE RecName: Full=Putative 3-methyladenine DNA glycosylase {ECO:0000255|HAMAP-Rule:MF_00527};
DE EC=3.2.2.- {ECO:0000255|HAMAP-Rule:MF_00527};
GN OrderedLocusNames=CLK_0705;
OS Clostridium botulinum (strain Loch Maree / Type A3).
OC Bacteria; Firmicutes; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=498214;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Loch Maree / Type A3;
RX PubMed=18060065; DOI=10.1371/journal.pone.0001271;
RA Smith T.J., Hill K.K., Foley B.T., Detter J.C., Munk A.C., Bruce D.C.,
RA Doggett N.A., Smith L.A., Marks J.D., Xie G., Brettin T.S.;
RT "Analysis of the neurotoxin complex genes in Clostridium botulinum A1-A4
RT and B1 strains: BoNT/A3, /Ba4 and /B1 clusters are located within
RT plasmids.";
RL PLoS ONE 2:E1271-E1271(2007).
CC -!- SIMILARITY: Belongs to the DNA glycosylase MPG family.
CC {ECO:0000255|HAMAP-Rule:MF_00527}.
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DR EMBL; CP000962; ACA54217.1; -; Genomic_DNA.
DR RefSeq; WP_012342349.1; NC_010520.1.
DR AlphaFoldDB; B1KZY0; -.
DR SMR; B1KZY0; -.
DR EnsemblBacteria; ACA54217; ACA54217; CLK_0705.
DR KEGG; cbl:CLK_0705; -.
DR HOGENOM; CLU_060471_0_2_9; -.
DR OMA; VEAYHHT; -.
DR Proteomes; UP000000722; Chromosome.
DR GO; GO:0003905; F:alkylbase DNA N-glycosylase activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0006284; P:base-excision repair; IEA:InterPro.
DR CDD; cd00540; AAG; 1.
DR Gene3D; 3.10.300.10; -; 1.
DR HAMAP; MF_00527; 3MGH; 1.
DR InterPro; IPR011034; Formyl_transferase-like_C_sf.
DR InterPro; IPR003180; MPG.
DR InterPro; IPR036995; MPG_sf.
DR PANTHER; PTHR10429; PTHR10429; 1.
DR Pfam; PF02245; Pur_DNA_glyco; 1.
DR SUPFAM; SSF50486; SSF50486; 1.
DR TIGRFAMs; TIGR00567; 3mg; 1.
PE 3: Inferred from homology;
KW DNA damage; DNA repair; Hydrolase.
FT CHAIN 1..203
FT /note="Putative 3-methyladenine DNA glycosylase"
FT /id="PRO_1000127759"
SQ SEQUENCE 203 AA; 23547 MW; A653FCA5D7328DDB CRC64;
MRLTRDFYAK DARVLAKELL GKVLVREVDG IKLKGKIVET EAYIGAIDKA SHAYGGRRTK
RTEPLYGKPG IAYVYFIYGK YFCFNIISKT EGEAEGVLIR ALEPLENINL ISKLRFNKEF
EELNNYQRKN ITSGPSKLCM AFNINRDNNW EDLCESSSLY VEDVLYNDFE IIETVRVGID
YAEEARDFLW RYYIKDNAFV SVK