FABG2_BRANA
ID FABG2_BRANA Reviewed; 328 AA.
AC Q93X67;
DT 04-JAN-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-2001, sequence version 1.
DT 03-AUG-2022, entry version 95.
DE RecName: Full=3-oxoacyl-[acyl-carrier-protein] reductase 2, chloroplastic;
DE EC=1.1.1.100;
DE AltName: Full=3-ketoacyl-acyl carrier protein reductase 2;
DE Flags: Precursor;
GN Name=bkr2;
OS Brassica napus (Rape).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica.
OX NCBI_TaxID=3708;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Jet neuf; TISSUE=Embryo;
RA McDonald F.S., White A.J., Elborough K.M., Slabas A.R.;
RL Submitted (JUN-2001) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a (3R)-hydroxyacyl-[ACP] + NADP(+) = a 3-oxoacyl-[ACP] + H(+)
CC + NADPH; Xref=Rhea:RHEA:17397, Rhea:RHEA-COMP:9916, Rhea:RHEA-
CC COMP:9945, ChEBI:CHEBI:15378, ChEBI:CHEBI:57783, ChEBI:CHEBI:58349,
CC ChEBI:CHEBI:78776, ChEBI:CHEBI:78827; EC=1.1.1.100;
CC -!- PATHWAY: Lipid metabolism; fatty acid biosynthesis.
CC -!- SUBUNIT: Homotetramer. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast. Plastid. Note=And non-
CC photosynthetic plastids. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AJ243084; CAC41363.1; -; mRNA.
DR RefSeq; NP_001302983.1; NM_001316054.1.
DR AlphaFoldDB; Q93X67; -.
DR SMR; Q93X67; -.
DR EnsemblPlants; CDY54831; CDY54831; GSBRNA2T00014699001.
DR GeneID; 106361756; -.
DR Gramene; CDY54831; CDY54831; GSBRNA2T00014699001.
DR KEGG; bna:106361756; -.
DR OMA; GESACCA; -.
DR UniPathway; UPA00094; -.
DR GO; GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
DR GO; GO:0004316; F:3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity; IEA:UniProtKB-EC.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-UniPathway.
DR InterPro; IPR011284; 3oxo_ACP_reduc.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020904; Sc_DH/Rdtase_CS.
DR InterPro; IPR002347; SDR_fam.
DR PRINTS; PR00081; GDHRDH.
DR PRINTS; PR00080; SDRFAMILY.
DR SUPFAM; SSF51735; SSF51735; 1.
DR TIGRFAMs; TIGR01830; 3oxo_ACP_reduc; 1.
DR PROSITE; PS00061; ADH_SHORT; 1.
PE 2: Evidence at transcript level;
KW Chloroplast; Fatty acid biosynthesis; Fatty acid metabolism;
KW Lipid biosynthesis; Lipid metabolism; NADP; Oxidoreductase; Plastid;
KW Transit peptide.
FT TRANSIT 1..66
FT /note="Chloroplast"
FT /evidence="ECO:0000255"
FT CHAIN 67..328
FT /note="3-oxoacyl-[acyl-carrier-protein] reductase 2,
FT chloroplastic"
FT /id="PRO_0000031978"
FT ACT_SITE 235
FT /note="Proton acceptor"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU10001"
FT BINDING 90..114
FT /ligand="NADP(+)"
FT /ligand_id="ChEBI:CHEBI:58349"
FT /evidence="ECO:0000250"
FT BINDING 222
FT /ligand="substrate"
FT /evidence="ECO:0000250"
SQ SEQUENCE 328 AA; 34374 MW; AFB61AF1C665545F CRC64;
MATTSIAGPR LTSLKTAAGK LGYREICHVR QWAPVHSPMP HFGMLRCGSR RPFATSSSTV
VQAQAQATAA EQSTGEEEAV PKVESPVVVV TGASRGIGKA IALSLGKAGC KVLVNYARSA
KEAEQVSKQI EAYGGQAITF GGDVSKEADV DAMMKTAVDA WGTIDVVVNN AGITRDTLLI
RMKKSQWDEV IDLNLTGVFL CTQAATKIMM KKRKGRIINI ASVVGLIGNI GQANYAAAKA
GVIGFSKTAA REGASRNINV NVVCPGFIAS DMTAKLGEDM EKKILGTIPL GRYGQPEDVA
GLVEFLALSP AASYITGQAF TIDGGIAI
