ID   AHSA2_BOVIN             Reviewed;         260 AA.
AC   A6QQC0;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   21-AUG-2007, sequence version 1.
DT   03-AUG-2022, entry version 74.
DE   RecName: Full=Activator of 90 kDa heat shock protein ATPase homolog 2;
GN   Name=AHSA2;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Thymus;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Co-chaperone that stimulates HSP90 ATPase activity.
CC       {ECO:0000250|UniProtKB:Q12449}.
CC   -!- SIMILARITY: Belongs to the AHA1 family. {ECO:0000305}.
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DR   EMBL; BC149756; AAI49757.1; -; mRNA.
DR   RefSeq; NP_001095604.1; NM_001102134.1.
DR   AlphaFoldDB; A6QQC0; -.
DR   SMR; A6QQC0; -.
DR   STRING; 9913.ENSBTAP00000050140; -.
DR   PaxDb; A6QQC0; -.
DR   PRIDE; A6QQC0; -.
DR   Ensembl; ENSBTAT00000055769; ENSBTAP00000050140; ENSBTAG00000006025.
DR   GeneID; 531017; -.
DR   KEGG; bta:531017; -.
DR   CTD; 268390; -.
DR   VEuPathDB; HostDB:ENSBTAG00000006025; -.
DR   VGNC; VGNC:108912; AHSA2.
DR   eggNOG; KOG2936; Eukaryota.
DR   GeneTree; ENSGT00940000157344; -.
DR   HOGENOM; CLU_049046_0_0_1; -.
DR   InParanoid; A6QQC0; -.
DR   OMA; CEVNQRK; -.
DR   OrthoDB; 1548191at2759; -.
DR   TreeFam; TF313680; -.
DR   Proteomes; UP000009136; Chromosome 11.
DR   Bgee; ENSBTAG00000006025; Expressed in oocyte and 105 other tissues.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0001671; F:ATPase activator activity; IBA:GO_Central.
DR   GO; GO:0051087; F:chaperone binding; IEA:InterPro.
DR   GO; GO:0051879; F:Hsp90 protein binding; IEA:InterPro.
DR   GO; GO:0032781; P:positive regulation of ATP-dependent activity; IBA:GO_Central.
DR   GO; GO:0006457; P:protein folding; IBA:GO_Central.
DR   Gene3D; 3.15.10.20; -; 1.
DR   Gene3D; 3.30.530.20; -; 1.
DR   InterPro; IPR036338; Aha1.
DR   InterPro; IPR039981; AHSA-like.
DR   InterPro; IPR015310; AHSA1_N.
DR   InterPro; IPR023393; START-like_dom_sf.
DR   PANTHER; PTHR13009; PTHR13009; 1.
DR   Pfam; PF09229; Aha1_N; 1.
DR   SMART; SM01000; Aha1_N; 1.
DR   SUPFAM; SSF103111; SSF103111; 1.
PE   2: Evidence at transcript level;
KW   Chaperone; Reference proteome; Stress response.
FT   CHAIN           1..260
FT                   /note="Activator of 90 kDa heat shock protein ATPase
FT                   homolog 2"
FT                   /id="PRO_0000315604"
SQ   SEQUENCE   260 AA;  29190 MW;  C217F3996FA992F0 CRC64;
     MAKWGQGDPR WIVEEREDGT NVNNWHWTER DATSWSKGRL RELLVGITVE NEAGRCEISE
     LKQVEGEASC SSRKGKLIFF YEWNIKLGWK GIIRESGAKH KGLIEIPSLS EENEVDDTEV
     NVSKKKGDGD ILKDLMKTAG TAKVREALGD YLKALKTEFT MGMILPTKAM AAQELTVERK
     LSENALQIQA SSRVALGVRI PTVALHMTEL FDTAIEQLYR IFTVKDLVQK FSKSPAVLEA
     EKGGKFQMLM ETSPVNIQNC