ID   AI3_DICCI               Reviewed;         243 AA.
AC   Q2LCQ5;
DT   04-DEC-2007, integrated into UniProtKB/Swiss-Prot.
DT   21-FEB-2006, sequence version 1.
DT   25-MAY-2022, entry version 39.
DE   RecName: Full=Probable intron-encoded endonuclease aI3;
DE            EC=3.1.-.-;
DE   AltName: Full=Cox1/2 intron3 ORF;
GN   Name=aI3;
OS   Dictyostelium citrinum (Slime mold).
OG   Mitochondrion.
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=361072;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=18413355; DOI=10.1093/molbev/msn088;
RA   Heidel A.J., Gloeckner G.;
RT   "Mitochondrial genome evolution in the social amoebae.";
RL   Mol. Biol. Evol. 25:1440-1450(2008).
CC   -!- FUNCTION: Mitochondrial DNA endonuclease involved in intron homing.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the LAGLIDADG endonuclease family.
CC       {ECO:0000305}.
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DR   EMBL; DQ336395; ABC60388.1; -; Genomic_DNA.
DR   RefSeq; YP_492637.1; NC_007787.2.
DR   AlphaFoldDB; Q2LCQ5; -.
DR   SMR; Q2LCQ5; -.
DR   GeneID; 9086868; -.
DR   GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR   GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0006314; P:intron homing; IEA:UniProtKB-KW.
DR   Gene3D; 3.10.28.10; -; 2.
DR   InterPro; IPR027434; Homing_endonucl.
DR   InterPro; IPR004860; LAGLIDADG_2.
DR   Pfam; PF00961; LAGLIDADG_1; 2.
DR   SUPFAM; SSF55608; SSF55608; 2.
PE   3: Inferred from homology;
KW   Endonuclease; Hydrolase; Intron homing; Mitochondrion; Nuclease.
FT   CHAIN           1..243
FT                   /note="Probable intron-encoded endonuclease aI3"
FT                   /id="PRO_0000312714"
SQ   SEQUENCE   243 AA;  29478 MW;  67FCF5CEEAC2EA6A CRC64;
     MKVEKRKIDT ESIKKFWVGL LEGSGSIQVN HWKKKNLQFR LEIKLKNCNE NFLMFKDIQK
     AIGGYIRFET SKKKERDQVV WIVDQKTEIE RIIKIFDQYA LLTKQKQDQL NFLKENLQRQ
     DVNWYLKERD NKYKVRVAHP DYKIKDITYF NEWLSGFVEA EGCFCIRTST YHSFSISQKY
     EKVLLSQIKE FFNITTQIKE SKKNIFLLEV YKKVILQKLI HHFIEYPLLG EKNKSFERFK
     NFF