ID   FABP_ACASI              Reviewed;          64 AA.
AC   O76821;
DT   20-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1999, sequence version 2.
DT   25-MAY-2022, entry version 72.
DE   RecName: Full=Fatty acid-binding protein;
DE   AltName: Allergen=Aca s 13;
DE   Flags: Fragment;
OS   Acarus siro (Flour mite) (Tyroglyphus farinae).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC   Acariformes; Sarcoptiformes; Astigmata; Acaroidea; Acaridae; Acarinae;
OC   Acarus.
OX   NCBI_TaxID=66546;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=10474032; DOI=10.1159/000024204;
RA   Eriksson T.L.J., Whitley P., Johansson E., van Hage-Hamsten M.,
RA   Gafvelin G.;
RT   "Identification and characterisation of two allergens from the dust mite
RT   Acarus siro, homologous with fatty acid-binding proteins.";
RL   Int. Arch. Allergy Immunol. 119:275-281(1999).
CC   -!- FUNCTION: FABP are thought to play a role in the intracellular
CC       transport of long-chain fatty acids and their acyl-CoA esters.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC   -!- DOMAIN: Forms a beta-barrel structure that accommodates hydrophobic
CC       ligands in its interior. {ECO:0000250}.
CC   -!- ALLERGEN: Causes an allergic reaction in human.
CC   -!- SIMILARITY: Belongs to the calycin superfamily. Fatty-acid binding
CC       protein (FABP) family. {ECO:0000305}.
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DR   EMBL; AJ006774; CAA07241.1; -; mRNA.
DR   AlphaFoldDB; O76821; -.
DR   SMR; O76821; -.
DR   Allergome; 2; Aca s 13.
DR   Allergome; 3051; Aca s 13.0101.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   Gene3D; 2.40.128.20; -; 1.
DR   InterPro; IPR012674; Calycin.
DR   InterPro; IPR000463; Fatty_acid-bd.
DR   InterPro; IPR031259; ILBP.
DR   InterPro; IPR000566; Lipocln_cytosolic_FA-bd_dom.
DR   PANTHER; PTHR11955; PTHR11955; 1.
DR   Pfam; PF00061; Lipocalin; 1.
DR   PRINTS; PR00178; FATTYACIDBP.
DR   SUPFAM; SSF50814; SSF50814; 1.
DR   PROSITE; PS00214; FABP; 1.
PE   1: Evidence at protein level;
KW   Allergen; Cytoplasm; Lipid-binding; Transport.
FT   CHAIN           <1..>64
FT                   /note="Fatty acid-binding protein"
FT                   /id="PRO_0000067419"
FT   NON_TER         1
FT   NON_TER         64
SQ   SEQUENCE   64 AA;  7059 MW;  030E8A9C0DF2E94A CRC64;
     QINGSYKLEK SDNFDAFLKE LGLNFVTRNL AKSATPTVEV SVNGDSYTIK TASTLKNTEI
     SFKL