AIG2C_ARATH
ID AIG2C_ARATH Reviewed; 165 AA.
AC Q9MBH1; Q8LBI2;
DT 02-NOV-2016, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 129.
DE RecName: Full=Protein AIG2 C {ECO:0000305};
DE EC=2.3.2.- {ECO:0000305};
DE AltName: Full=Avirulence-induced gene 2 protein C {ECO:0000305};
DE AltName: Full=Putative gamma-glutamylcyclotransferase {ECO:0000250|UniProtKB:O75223};
GN Name=AIG2C {ECO:0000305};
GN OrderedLocusNames=At3g28950 {ECO:0000312|Araport:AT3G28950};
GN ORFNames=K5K13.6 {ECO:0000312|EMBL:BAA95746.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000312|EMBL:BAA95746.1};
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10819329; DOI=10.1093/dnares/7.2.131;
RA Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 3. I. Sequence
RT features of the regions of 4,504,864 bp covered by sixty P1 and TAC
RT clones.";
RL DNA Res. 7:131-135(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP STRUCTURE BY NMR OF 2-165, AND GENE FAMILY.
RX PubMed=18214976; DOI=10.1002/prot.21936;
RA de la Cruz N.B., Peterson F.C., Volkman B.F.;
RT "Solution structure of At3g28950 from Arabidopsis thaliana.";
RL Proteins 71:546-551(2008).
CC -!- FUNCTION: Putative gamma-glutamylcyclotransferase.
CC {ECO:0000250|UniProtKB:O75223}.
CC -!- TISSUE SPECIFICITY: Expressed in floral organs, leaves, stems and
CC roots. {ECO:0000305|PubMed:18214976}.
CC -!- DEVELOPMENTAL STAGE: Expressed constitutively during the life cycle.
CC {ECO:0000305|PubMed:18214976}.
CC -!- INDUCTION: Expressed constitutively. {ECO:0000305|PubMed:18214976}.
CC -!- SIMILARITY: Belongs to the gamma-glutamylcyclotransferase family.
CC {ECO:0000305}.
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DR EMBL; AB025615; BAA95746.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE77512.1; -; Genomic_DNA.
DR EMBL; BT004596; AAO42842.1; -; mRNA.
DR EMBL; AK227989; BAE99955.1; -; mRNA.
DR EMBL; AY087193; AAM64749.1; -; mRNA.
DR RefSeq; NP_189537.1; NM_113816.3.
DR PDB; 2JQV; NMR; -; A=2-165.
DR PDBsum; 2JQV; -.
DR AlphaFoldDB; Q9MBH1; -.
DR SMR; Q9MBH1; -.
DR PaxDb; Q9MBH1; -.
DR PRIDE; Q9MBH1; -.
DR ProteomicsDB; 244934; -.
DR DNASU; 822532; -.
DR EnsemblPlants; AT3G28950.1; AT3G28950.1; AT3G28950.
DR GeneID; 822532; -.
DR Gramene; AT3G28950.1; AT3G28950.1; AT3G28950.
DR KEGG; ath:AT3G28950; -.
DR Araport; AT3G28950; -.
DR TAIR; locus:2086997; AT3G28950.
DR eggNOG; ENOG502S7T1; Eukaryota.
DR HOGENOM; CLU_093936_0_0_1; -.
DR InParanoid; Q9MBH1; -.
DR OMA; DFEEWRV; -.
DR OrthoDB; 1307538at2759; -.
DR PhylomeDB; Q9MBH1; -.
DR EvolutionaryTrace; Q9MBH1; -.
DR PRO; PR:Q9MBH1; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9MBH1; baseline and differential.
DR GO; GO:0016746; F:acyltransferase activity; IEA:UniProtKB-KW.
DR CDD; cd06661; GGCT_like; 1.
DR InterPro; IPR045038; AIG2-like.
DR InterPro; IPR009288; AIG2-like_dom.
DR InterPro; IPR013024; GGCT-like.
DR InterPro; IPR036568; GGCT-like_sf.
DR PANTHER; PTHR31544; PTHR31544; 1.
DR Pfam; PF06094; GGACT; 1.
DR SUPFAM; SSF110857; SSF110857; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Acyltransferase; Reference proteome; Transferase.
FT CHAIN 1..165
FT /note="Protein AIG2 C"
FT /id="PRO_0000438021"
FT ACT_SITE 82
FT /note="Proton acceptor"
FT /evidence="ECO:0000250|UniProtKB:O75223"
FT BINDING 14..19
FT /ligand="substrate"
FT /evidence="ECO:0000250|UniProtKB:O75223"
FT CONFLICT 106
FT /note="T -> S (in Ref. 5; AAM64749)"
FT /evidence="ECO:0000305"
FT STRAND 9..15
FT /evidence="ECO:0007829|PDB:2JQV"
FT HELIX 20..26
FT /evidence="ECO:0007829|PDB:2JQV"
FT STRAND 32..39
FT /evidence="ECO:0007829|PDB:2JQV"
FT STRAND 49..51
FT /evidence="ECO:0007829|PDB:2JQV"
FT STRAND 54..56
FT /evidence="ECO:0007829|PDB:2JQV"
FT STRAND 59..70
FT /evidence="ECO:0007829|PDB:2JQV"
FT HELIX 72..80
FT /evidence="ECO:0007829|PDB:2JQV"
FT STRAND 84..95
FT /evidence="ECO:0007829|PDB:2JQV"
FT TURN 96..98
FT /evidence="ECO:0007829|PDB:2JQV"
FT STRAND 101..109
FT /evidence="ECO:0007829|PDB:2JQV"
FT TURN 110..113
FT /evidence="ECO:0007829|PDB:2JQV"
FT HELIX 123..146
FT /evidence="ECO:0007829|PDB:2JQV"
FT HELIX 153..156
FT /evidence="ECO:0007829|PDB:2JQV"
SQ SEQUENCE 165 AA; 18619 MW; 883C189FD8C55DDF CRC64;
MTSSDPQSHN VFVYGSILEP AVAAVILDRT ADTVPAVLHG YHRYKLKGLP YPCIVSSDSG
KVNGKVITGV SDAELNNFDV IEGNDYERVT VEVVRMDNSE KVKVETYVWV NKDDPRMYGE
WDFEEWRVVH AEKFVETFRK MLEWNKNPNG KSMEEAVGSL LSSGD
