AIGLA_ARATH
ID AIGLA_ARATH Reviewed; 165 AA.
AC Q9FIX2; Q58CN3; Q680A3;
DT 03-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 105.
DE RecName: Full=AIG2-like protein A {ECO:0000305};
DE EC=2.3.2.- {ECO:0000305};
DE AltName: Full=AIG2-like protein {ECO:0000303|PubMed:16754964};
DE AltName: Full=Avirulence-induced gene 2-like protein {ECO:0000303|PubMed:16754964};
DE AltName: Full=Avirulence-induced gene 2-like protein A {ECO:0000305};
DE AltName: Full=Putative gamma-glutamylcyclotransferase {ECO:0000250|UniProtKB:O75223};
GN Name=AIG2LA {ECO:0000305};
GN OrderedLocusNames=At5g39720 {ECO:0000312|Araport:AT5G39720};
GN ORFNames=MIJ24.180, MKM21.1, MKM21.3 {ECO:0000312|EMBL:BAB11378.1},
GN MKM21_10;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9872454; DOI=10.1093/dnares/5.5.297;
RA Nakamura Y., Sato S., Asamizu E., Kaneko T., Kotani H., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. VII. Sequence
RT features of the regions of 1,013,767 bp covered by sixteen physically
RT assigned P1 and TAC clones.";
RL DNA Res. 5:297-308(1998).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Shinn P., Chen H., Cheuk R.F., Kim C.J., Ecker J.R.;
RT "Arabidopsis cDNA clones.";
RL Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 104-165.
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP GENE FAMILY.
RX PubMed=18214976; DOI=10.1002/prot.21936;
RA de la Cruz N.B., Peterson F.C., Volkman B.F.;
RT "Solution structure of At3g28950 from Arabidopsis thaliana.";
RL Proteins 71:546-551(2008).
RN [6]
RP STRUCTURE BY NMR OF 2-165.
RX PubMed=16754964; DOI=10.1107/s1744309106015946;
RA Lytle B.L., Peterson F.C., Tyler E.M., Newman C.L., Vinarov D.A.,
RA Markley J.L., Volkman B.F.;
RT "Solution structure of Arabidopsis thaliana protein At5g39720.1, a member
RT of the AIG2-like protein family.";
RL Acta Crystallogr. F 62:490-493(2006).
CC -!- FUNCTION: Putative gamma-glutamylcyclotransferase.
CC {ECO:0000250|UniProtKB:O75223}.
CC -!- TISSUE SPECIFICITY: Expressed only in seeds.
CC {ECO:0000305|PubMed:18214976}.
CC -!- DEVELOPMENTAL STAGE: Expressed at the end of flowering and during seed
CC maturation. {ECO:0000305|PubMed:18214976}.
CC -!- INDUCTION: Not regulated by chemical or biotic treatments.
CC {ECO:0000305|PubMed:18214976}.
CC -!- SIMILARITY: Belongs to the gamma-glutamylcyclotransferase family.
CC {ECO:0000305}.
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DR EMBL; AB016876; BAB11378.1; -; Genomic_DNA.
DR EMBL; CP002688; AED94467.1; -; Genomic_DNA.
DR EMBL; BT021914; AAX49363.1; -; mRNA.
DR EMBL; AK175964; BAD43727.1; -; mRNA.
DR RefSeq; NP_198788.1; NM_123334.3.
DR PDB; 2G0Q; NMR; -; A=2-165.
DR PDBsum; 2G0Q; -.
DR AlphaFoldDB; Q9FIX2; -.
DR BMRB; Q9FIX2; -.
DR SMR; Q9FIX2; -.
DR PaxDb; Q9FIX2; -.
DR PRIDE; Q9FIX2; -.
DR ProteomicsDB; 245035; -.
DR DNASU; 833968; -.
DR EnsemblPlants; AT5G39720.1; AT5G39720.1; AT5G39720.
DR GeneID; 833968; -.
DR Gramene; AT5G39720.1; AT5G39720.1; AT5G39720.
DR KEGG; ath:AT5G39720; -.
DR Araport; AT5G39720; -.
DR TAIR; locus:2164915; AT5G39720.
DR eggNOG; ENOG502SWGU; Eukaryota.
DR HOGENOM; CLU_093936_0_0_1; -.
DR InParanoid; Q9FIX2; -.
DR OMA; MECKKKP; -.
DR OrthoDB; 1307538at2759; -.
DR PhylomeDB; Q9FIX2; -.
DR EvolutionaryTrace; Q9FIX2; -.
DR PRO; PR:Q9FIX2; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9FIX2; baseline and differential.
DR Genevisible; Q9FIX2; AT.
DR GO; GO:0016746; F:acyltransferase activity; IEA:UniProtKB-KW.
DR CDD; cd06661; GGCT_like; 1.
DR InterPro; IPR045038; AIG2-like.
DR InterPro; IPR009288; AIG2-like_dom.
DR InterPro; IPR013024; GGCT-like.
DR InterPro; IPR036568; GGCT-like_sf.
DR PANTHER; PTHR31544; PTHR31544; 1.
DR Pfam; PF06094; GGACT; 1.
DR SUPFAM; SSF110857; SSF110857; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Acyltransferase; Reference proteome; Transferase.
FT CHAIN 1..165
FT /note="AIG2-like protein A"
FT /id="PRO_0000250588"
FT ACT_SITE 83
FT /note="Proton acceptor"
FT /evidence="ECO:0000250|UniProtKB:O75223"
FT BINDING 15..20
FT /ligand="substrate"
FT /evidence="ECO:0000250|UniProtKB:O75223"
FT CONFLICT 157..158
FT /note="IS -> MA (in Ref. 3; AAX49363)"
FT /evidence="ECO:0000305"
FT CONFLICT 159..165
FT /note="Missing (in Ref. 3; AAX49363)"
FT /evidence="ECO:0000305"
FT STRAND 7..14
FT /evidence="ECO:0007829|PDB:2G0Q"
FT HELIX 17..19
FT /evidence="ECO:0007829|PDB:2G0Q"
FT HELIX 21..27
FT /evidence="ECO:0007829|PDB:2G0Q"
FT STRAND 33..40
FT /evidence="ECO:0007829|PDB:2G0Q"
FT STRAND 49..51
FT /evidence="ECO:0007829|PDB:2G0Q"
FT STRAND 62..71
FT /evidence="ECO:0007829|PDB:2G0Q"
FT HELIX 73..83
FT /evidence="ECO:0007829|PDB:2G0Q"
FT TURN 84..86
FT /evidence="ECO:0007829|PDB:2G0Q"
FT STRAND 87..100
FT /evidence="ECO:0007829|PDB:2G0Q"
FT STRAND 102..111
FT /evidence="ECO:0007829|PDB:2G0Q"
FT STRAND 116..118
FT /evidence="ECO:0007829|PDB:2G0Q"
FT HELIX 123..146
FT /evidence="ECO:0007829|PDB:2G0Q"
SQ SEQUENCE 165 AA; 19103 MW; DF6ADBF2F5800E4D CRC64;
MCSSDSLQLH NVFVYGSFQD PDVINVMLDR TPEIVSATLP GFQRFRLKGR LYPCIVPSEK
GEVHGKVLMG VTSDELENLD AVEGNEYERV TVGIVREDNS EKMAVKTYMW INKADPDMFG
EWNFEEWKRL HKKKFIETFK KIMECKKKPQ GQGNDDISHV LREDQ
