AIL1_ARATH
ID AIL1_ARATH Reviewed; 415 AA.
AC Q1PFE1; A0MEG0; Q6J335; Q9CAH3;
DT 12-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT 16-MAY-2006, sequence version 1.
DT 03-AUG-2022, entry version 109.
DE RecName: Full=AP2-like ethylene-responsive transcription factor AIL1 {ECO:0000303|PubMed:15988559};
DE AltName: Full=Protein AINTEGUMENTA-LIKE 1 {ECO:0000303|PubMed:15988559};
GN Name=AIL1 {ECO:0000303|PubMed:15988559};
GN OrderedLocusNames=At1g72570 {ECO:0000312|Araport:AT1G72570};
GN ORFNames=F28P22.24 {ECO:0000312|EMBL:AAG51860.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RA Pan Y., Gong W., Liu D., Fu Q., Mei W.-Q., Song W.-Q., Ma L.-G., Luo J.-C.,
RA Deng X.-W., Zhu Y.-X.;
RT "Molecular cloning, expression, phylogenetic and functional
RT characterization of the Arabidopsis AP2/EREBP transcription factor
RT family.";
RL Submitted (APR-2004) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=17147637; DOI=10.1111/j.1467-7652.2006.00183.x;
RA Underwood B.A., Vanderhaeghen R., Whitford R., Town C.D., Hilson P.;
RT "Simultaneous high-throughput recombinational cloning of open reading
RT frames in closed and open configurations.";
RL Plant Biotechnol. J. 4:317-324(2006).
RN [5]
RP TISSUE SPECIFICITY.
RX PubMed=15988559; DOI=10.1007/s11103-005-0955-6;
RA Nole-Wilson S., Tranby T.L., Krizek B.A.;
RT "AINTEGUMENTA-like (AIL) genes are expressed in young tissues and may
RT specify meristematic or division-competent states.";
RL Plant Mol. Biol. 57:613-628(2005).
RN [6]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=16407444; DOI=10.1104/pp.105.073783;
RA Nakano T., Suzuki K., Fujimura T., Shinshi H.;
RT "Genome-wide analysis of the ERF gene family in Arabidopsis and rice.";
RL Plant Physiol. 140:411-432(2006).
RN [7]
RP INTERACTION WITH ANL2; HDG2; HDG10; GL2; HDG3; ATML1 AND PDF2.
RC STRAIN=cv. Columbia;
RX PubMed=25564655; DOI=10.1242/dev.117168;
RA Horstman A., Fukuoka H., Muino J.M., Nitsch L., Guo C., Passarinho P.,
RA Sanchez-Perez G., Immink R., Angenent G., Boutilier K.;
RT "AIL and HDG proteins act antagonistically to control cell proliferation.";
RL Development 142:454-464(2015).
CC -!- FUNCTION: Probably acts as a transcriptional activator. Binds to the
CC GCC-box pathogenesis-related promoter element. May be involved in the
CC regulation of gene expression by stress factors and by components of
CC stress signal transduction pathways. {ECO:0000250|UniProtKB:Q9LND1}.
CC -!- SUBUNIT: Interacts with ANL2, HDG2 and HDG10, and possibly with GL2,
CC HDG3, ATML1 and PDF2. {ECO:0000269|PubMed:25564655}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Expressed in roots, seedlings, inflorescence, and
CC siliques. Also detected at low levels in leaves.
CC {ECO:0000269|PubMed:15988559}.
CC -!- SIMILARITY: Belongs to the AP2/ERF transcription factor family. AP2
CC subfamily. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAG51860.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=ABK28464.1; Type=Erroneous termination; Note=Extended C-terminus.; Evidence={ECO:0000305};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AY603417; AAT12507.1; -; mRNA.
DR EMBL; AC010926; AAG51860.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE35343.1; -; Genomic_DNA.
DR EMBL; DQ446422; ABE65765.1; -; mRNA.
DR EMBL; DQ652930; ABK28464.1; ALT_SEQ; mRNA.
DR PIR; B96750; B96750.
DR RefSeq; NP_177401.2; NM_105916.2.
DR AlphaFoldDB; Q1PFE1; -.
DR SMR; Q1PFE1; -.
DR BioGRID; 28808; 12.
DR IntAct; Q1PFE1; 12.
DR STRING; 3702.AT1G72570.1; -.
DR PaxDb; Q1PFE1; -.
DR PRIDE; Q1PFE1; -.
DR ProteomicsDB; 245036; -.
DR EnsemblPlants; AT1G72570.1; AT1G72570.1; AT1G72570.
DR GeneID; 843589; -.
DR Gramene; AT1G72570.1; AT1G72570.1; AT1G72570.
DR KEGG; ath:AT1G72570; -.
DR Araport; AT1G72570; -.
DR TAIR; locus:2030265; AT1G72570.
DR eggNOG; ENOG502QYT4; Eukaryota.
DR HOGENOM; CLU_013549_6_0_1; -.
DR InParanoid; Q1PFE1; -.
DR OMA; SHQTEYP; -.
DR OrthoDB; 455685at2759; -.
DR PhylomeDB; Q1PFE1; -.
DR PRO; PR:Q1PFE1; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q1PFE1; baseline and differential.
DR Genevisible; Q1PFE1; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IPI:TAIR.
DR GO; GO:0009873; P:ethylene-activated signaling pathway; IEA:UniProtKB-KW.
DR CDD; cd00018; AP2; 2.
DR Gene3D; 3.30.730.10; -; 2.
DR InterPro; IPR001471; AP2/ERF_dom.
DR InterPro; IPR036955; AP2/ERF_dom_sf.
DR InterPro; IPR016177; DNA-bd_dom_sf.
DR Pfam; PF00847; AP2; 2.
DR PRINTS; PR00367; ETHRSPELEMNT.
DR SMART; SM00380; AP2; 2.
DR SUPFAM; SSF54171; SSF54171; 2.
DR PROSITE; PS51032; AP2_ERF; 2.
PE 1: Evidence at protein level;
KW Activator; DNA-binding; Ethylene signaling pathway; Nucleus;
KW Reference proteome; Repeat; Transcription; Transcription regulation.
FT CHAIN 1..415
FT /note="AP2-like ethylene-responsive transcription factor
FT AIL1"
FT /id="PRO_0000290362"
FT DNA_BIND 223..289
FT /note="AP2/ERF 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00366"
FT DNA_BIND 325..383
FT /note="AP2/ERF 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00366"
FT CONFLICT 96
FT /note="Y -> F (in Ref. 1; AAT12507)"
FT /evidence="ECO:0000305"
FT CONFLICT 116
FT /note="V -> F (in Ref. 1; AAT12507)"
FT /evidence="ECO:0000305"
FT CONFLICT 119..120
FT /note="FK -> SN (in Ref. 1; AAT12507)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 415 AA; 47133 MW; 669EE2618C868DC7 CRC64;
MKKWLGFSLT PPLRICNSEE EELRHDGSDV WRYDINFDHH HHDEDVPKVE DLLSNSHQTE
YPINHNQTNV NCTTVVNRLN PPGYLLHDQT VVTPHYPNLD PNLSNDYGGF ERVGSVSVFK
SWLEQGTPAF PLSSHYVTEE AGTSNNISHF SNEETGYNTN GSMLSLALSH GACSDLINES
NVSARVEEPV KVDEKRKRLV VKPQVKESVP RKSVDSYGQR TSQYRGVTRH RWTGRYEAHL
WDNSCKKEGQ TRRGRQVYLG GYDEEEKAAR AYDLAALKYW GPTTHLNFPL SNYEKEIEEL
NNMNRQEFVA MLRRNSSGFS RGASVYRGVT RHHQHGRWQA RIGRVAGNKD LYLGTFSTQE
EAAEAYDIAA IKFRGLNAVT NFDINRYDVK RICSSSTIVD SDQAKHSPTS SGAGH
