AIL6_ARATH
ID AIL6_ARATH Reviewed; 581 AA.
AC Q52QU2; Q6PQQ5; Q9LXA3;
DT 21-AUG-2007, integrated into UniProtKB/Swiss-Prot.
DT 24-MAY-2005, sequence version 1.
DT 03-AUG-2022, entry version 110.
DE RecName: Full=AP2-like ethylene-responsive transcription factor AIL6 {ECO:0000303|PubMed:15988559};
DE AltName: Full=Protein AINTEGUMENTA-LIKE 6 {ECO:0000303|PubMed:15988559};
GN Name=AIL6 {ECO:0000303|PubMed:15988559};
GN OrderedLocusNames=At5g10510 {ECO:0000312|Araport:AT5G10510};
GN ORFNames=F12B17.140 {ECO:0000312|EMBL:CAB89392.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), AND TISSUE SPECIFICITY.
RC STRAIN=cv. Columbia;
RX PubMed=16307362; DOI=10.1007/s11103-005-1511-0;
RA Feng J.-X., Liu D., Pan Y., Gong W., Ma L.-G., Luo J.-C., Deng X.-W.,
RA Zhu Y.-X.;
RT "An annotation update via cDNA sequence analysis and comprehensive
RT profiling of developmental, hormonal or environmental responsiveness of the
RT Arabidopsis AP2/EREBP transcription factor gene family.";
RL Plant Mol. Biol. 59:853-868(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130714; DOI=10.1038/35048507;
RA Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
RA Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M.,
RA Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.,
RA Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M.,
RA Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L.,
RA O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D.,
RA Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M.,
RA Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L.,
RA Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B.,
RA Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P.,
RA Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M.,
RA Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D.,
RA Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A.,
RA Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
RA Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T.,
RA Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A.,
RA McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U.,
RA Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W.,
RA Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M.,
RA Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S.,
RA Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G.,
RA Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W.,
RA Bevan M., Fransz P.F.;
RT "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.";
RL Nature 408:823-826(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 16-581 (ISOFORM 2).
RA Pan Y., Gong W., Liu D., Fu Q., Mei W.-Q., Song W.-Q., Ma L.-G., Luo J.-C.,
RA Deng X.-W., Zhu Y.-X.;
RT "Molecular cloning, expression, phylogenetic and functional
RT characterization of the Arabidopsis AP2/EREBP transcription factor
RT family.";
RL Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP TISSUE SPECIFICITY, AND DEVELOPMENTAL STAGE.
RX PubMed=15988559; DOI=10.1007/s11103-005-0955-6;
RA Nole-Wilson S., Tranby T.L., Krizek B.A.;
RT "AINTEGUMENTA-like (AIL) genes are expressed in young tissues and may
RT specify meristematic or division-competent states.";
RL Plant Mol. Biol. 57:613-628(2005).
RN [6]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=16407444; DOI=10.1104/pp.105.073783;
RA Nakano T., Suzuki K., Fujimura T., Shinshi H.;
RT "Genome-wide analysis of the ERF gene family in Arabidopsis and rice.";
RL Plant Physiol. 140:411-432(2006).
CC -!- FUNCTION: Probably acts as a transcriptional activator. Binds to the
CC GCC-box pathogenesis-related promoter element. May be involved in the
CC regulation of gene expression by stress factors and by components of
CC stress signal transduction pathways. {ECO:0000250|UniProtKB:Q9LND1}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q52QU2-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q52QU2-2; Sequence=VSP_027406;
CC -!- TISSUE SPECIFICITY: Expressed in roots, seedlings, hypocotyl,
CC inflorescence, siliques, and pistils. Also detected at low levels in
CC leaves. {ECO:0000269|PubMed:15988559, ECO:0000269|PubMed:16307362}.
CC -!- DEVELOPMENTAL STAGE: Detected in inflorescence and youg floral
CC mersitems, and in stem procambial cells. In floral mersitems, mostly
CC expressed in the central dome. Disappears progressively from sepal
CC primordia, but accumulates in second, third and fourth whorl organ
CC primordia. Later, confined to occasional patches in stamens and in
CC petal before disparearing progressively from flowers.
CC {ECO:0000269|PubMed:15988559}.
CC -!- SIMILARITY: Belongs to the AP2/ERF transcription factor family. AP2
CC subfamily. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAB89392.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AY974197; AAX89123.1; -; mRNA.
DR EMBL; AL353995; CAB89392.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002688; ANM69603.1; -; Genomic_DNA.
DR EMBL; CP002688; ANM69605.1; -; Genomic_DNA.
DR EMBL; AY585683; AAS97940.1; -; mRNA.
DR PIR; T49988; T49988.
DR RefSeq; NP_001331268.1; NM_001343118.1. [Q52QU2-2]
DR RefSeq; NP_001331270.1; NM_001343116.1. [Q52QU2-2]
DR RefSeq; NP_196613.2; NM_121089.3.
DR AlphaFoldDB; Q52QU2; -.
DR SMR; Q52QU2; -.
DR BioGRID; 16193; 2.
DR STRING; 3702.AT5G10510.3; -.
DR PaxDb; Q52QU2; -.
DR PeptideAtlas; Q52QU2; -.
DR PRIDE; Q52QU2; -.
DR ProteomicsDB; 244920; -. [Q52QU2-1]
DR EnsemblPlants; AT5G10510.4; AT5G10510.4; AT5G10510. [Q52QU2-2]
DR EnsemblPlants; AT5G10510.6; AT5G10510.6; AT5G10510. [Q52QU2-2]
DR GeneID; 830915; -.
DR Gramene; AT5G10510.4; AT5G10510.4; AT5G10510. [Q52QU2-2]
DR Gramene; AT5G10510.6; AT5G10510.6; AT5G10510. [Q52QU2-2]
DR KEGG; ath:AT5G10510; -.
DR Araport; AT5G10510; -.
DR eggNOG; ENOG502QWA0; Eukaryota.
DR HOGENOM; CLU_013549_4_0_1; -.
DR InParanoid; Q52QU2; -.
DR OMA; HYFLDNF; -.
DR PhylomeDB; Q52QU2; -.
DR PRO; PR:Q52QU2; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q52QU2; baseline and differential.
DR Genevisible; Q52QU2; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0009873; P:ethylene-activated signaling pathway; IEA:UniProtKB-KW.
DR CDD; cd00018; AP2; 2.
DR Gene3D; 3.30.730.10; -; 2.
DR InterPro; IPR001471; AP2/ERF_dom.
DR InterPro; IPR036955; AP2/ERF_dom_sf.
DR InterPro; IPR016177; DNA-bd_dom_sf.
DR Pfam; PF00847; AP2; 2.
DR PRINTS; PR00367; ETHRSPELEMNT.
DR SMART; SM00380; AP2; 2.
DR SUPFAM; SSF54171; SSF54171; 2.
DR PROSITE; PS51032; AP2_ERF; 2.
PE 2: Evidence at transcript level;
KW Activator; Alternative splicing; DNA-binding; Ethylene signaling pathway;
KW Nucleus; Reference proteome; Repeat; Transcription;
KW Transcription regulation.
FT CHAIN 1..581
FT /note="AP2-like ethylene-responsive transcription factor
FT AIL6"
FT /id="PRO_0000297917"
FT DNA_BIND 268..331
FT /note="AP2/ERF 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00366"
FT DNA_BIND 367..425
FT /note="AP2/ERF 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00366"
FT REGION 105..132
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 205..240
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 105..128
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 301
FT /note="Q -> QVYL (in isoform 2)"
FT /evidence="ECO:0000303|Ref.4"
FT /id="VSP_027406"
SQ SEQUENCE 581 AA; 64966 MW; 260C358B3AB11903 CRC64;
MMAPMTNWLT FSLSPMEMLR SSDQSQFVSY DASSAASSSP YLLDNFYGWS NQKPQEFFKE
EAQLAAAASM ADSTILTTFV DPQSHHSQNH IPKLEDFLGD SSSIVRYSDN SQTDTQDSSL
TQIYDPRHHH NQTGFYSDHH DFKTMAGFQS AFSTNSGSEV DDSASIGRTH LAGDYLGHVV
ESSGPELGFH GGSTGALSLG VNVNNNTNHR NDNDNHYRGN NNGERINNNN NNDNEKTDSE
KEKAVVAVET SDCSNKKIAD TFGQRTSIYR GVTRHRWTGR YEAHLWDNSC RREGQARKGR
QGGYDKEDKA ARAYDLAALK YWNATATTNF PITNYSKEVE EMKHMTKQEF IASLRRKSSG
FSRGASIYRG VTRHHQQGRW QARIGRVAGN KDLYLGTFAT EEEAAEAYDI AAIKFRGINA
VTNFEMNRYD VEAIMKSALP IGGAAKRLKL SLEAAASSEQ KPILGHHQLH HFQQQQQQQQ
LQLQSSPNHS SINFALCPNS AVQSQQIIPC GIPFEAAALY HHHQQQQQHQ QQQQQQNFFQ
HFPANAASDS TGSNNNSNVQ GTMGLMAPNP AEFFLWPNQS Y
