ID   AIL_YEREN               Reviewed;         178 AA.
AC   P16454; Q9FCY3;
DT   01-AUG-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1990, sequence version 1.
DT   25-MAY-2022, entry version 98.
DE   RecName: Full=Attachment invasion locus protein;
DE   Flags: Precursor;
GN   Name=ail;
OS   Yersinia enterocolitica.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=630;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND PROTEIN SEQUENCE OF 24-33.
RX   PubMed=1688838; DOI=10.1128/jb.172.2.1062-1069.1990;
RA   Miller V.L., Bliska J.B., Falkow S.;
RT   "Nucleotide sequence of the Yersinia enterocolitica ail gene and
RT   characterization of the Ail protein product.";
RL   J. Bacteriol. 172:1062-1069(1990).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 20-160.
RA   Gierczynski R., Jagielski M.;
RL   Submitted (JUL-2000) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Promotes the invasion of pathogenic bacteria into eukaryotic
CC       cells by an unknown mechanism.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000250}; Multi-pass
CC       membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the outer membrane OOP (TC 1.B.6) superfamily.
CC       Ail family. {ECO:0000305}.
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DR   EMBL; M29945; AAA88694.1; -; Genomic_DNA.
DR   EMBL; AY004311; AAF97354.1; -; Genomic_DNA.
DR   PIR; A35123; A35123.
DR   RefSeq; WP_005166773.1; NZ_NWMR01000104.1.
DR   AlphaFoldDB; P16454; -.
DR   SMR; P16454; -.
DR   OrthoDB; 2018542at2; -.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0044384; C:host outer membrane; IEA:InterPro.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR000758; Enterovir_OMP.
DR   InterPro; IPR011250; OMP/PagP_b-brl.
DR   InterPro; IPR027385; OMP_b-brl.
DR   Pfam; PF13505; OMP_b-brl; 1.
DR   PRINTS; PR00316; ENTEROVIROMP.
DR   SUPFAM; SSF56925; SSF56925; 1.
DR   PROSITE; PS00694; ENT_VIR_OMP_1; 1.
DR   PROSITE; PS00695; ENT_VIR_OMP_2; 1.
PE   1: Evidence at protein level;
KW   Cell outer membrane; Direct protein sequencing; Membrane; Signal;
KW   Transmembrane; Transmembrane beta strand; Virulence.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000269|PubMed:1688838"
FT   CHAIN           24..178
FT                   /note="Attachment invasion locus protein"
FT                   /id="PRO_0000020197"
FT   CONFLICT        27
FT                   /note="S -> N (in Ref. 2; AAF97354)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        91
FT                   /note="V -> L (in Ref. 2; AAF97354)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        123
FT                   /note="A -> S (in Ref. 2; AAF97354)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        128
FT                   /note="E -> G (in Ref. 2; AAF97354)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        130
FT                   /note="I -> V (in Ref. 2; AAF97354)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        132
FT                   /note="A -> T (in Ref. 2; AAF97354)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   178 AA;  19548 MW;  D46FC92E2524F162 CRC64;
     MKKTLLASSL IACLSIASVN VYAASESSIS IGYAQSHVKE NGYTLDNDPK GFNLKYRYEL
     DDNWGVIGSF AYTHQGYDFF YGSNKFGHGD VDYYSVTMGP SFRINEYVSL YGLLGAAHGK
     VKASVFDESI SASKTSMAYG AGVQFNPLPN FVIDASYEYS KLDSIKVGTW MLGAGYRF