ID   AIL_YERPS               Reviewed;         182 AA.
AC   Q56957; Q667X3;
DT   15-JUL-1999, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 2.
DT   25-MAY-2022, entry version 109.
DE   RecName: Full=Attachment invasion locus protein;
DE   Flags: Precursor;
GN   Name=ail; OrderedLocusNames=YPTB2867;
OS   Yersinia pseudotuberculosis serotype I (strain IP32953).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=273123;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=YPIII / Serotype O:3;
RX   PubMed=8698470; DOI=10.1128/iai.64.7.2483-2489.1996;
RA   Yang Y., Merriam J.J., Mueller J.P., Isberg R.R.;
RT   "The psa locus is responsible for thermoinducible binding of Yersinia
RT   pseudotuberculosis to cultured cells.";
RL   Infect. Immun. 64:2483-2489(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IP32953;
RX   PubMed=15358858; DOI=10.1073/pnas.0404012101;
RA   Chain P.S.G., Carniel E., Larimer F.W., Lamerdin J., Stoutland P.O.,
RA   Regala W.M., Georgescu A.M., Vergez L.M., Land M.L., Motin V.L.,
RA   Brubaker R.R., Fowler J., Hinnebusch J., Marceau M., Medigue C.,
RA   Simonet M., Chenal-Francisque V., Souza B., Dacheux D., Elliott J.M.,
RA   Derbise A., Hauser L.J., Garcia E.;
RT   "Insights into the evolution of Yersinia pestis through whole-genome
RT   comparison with Yersinia pseudotuberculosis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:13826-13831(2004).
CC   -!- FUNCTION: Promotes the invasion of pathogenic bacteria into eukaryotic
CC       cells by an unknown mechanism. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000250}; Multi-pass
CC       membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the outer membrane OOP (TC 1.B.6) superfamily.
CC       Ail family. {ECO:0000305}.
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DR   EMBL; L49439; AAB36601.1; -; Genomic_DNA.
DR   EMBL; BX936398; CAH22105.1; -; Genomic_DNA.
DR   RefSeq; WP_011192817.1; NZ_CP009712.1.
DR   AlphaFoldDB; Q56957; -.
DR   BMRB; Q56957; -.
DR   SMR; Q56957; -.
DR   EnsemblBacteria; CAH22105; CAH22105; YPTB2867.
DR   GeneID; 66844711; -.
DR   KEGG; yps:YPTB2867; -.
DR   OMA; LYGNVGM; -.
DR   Proteomes; UP000001011; Chromosome.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0044384; C:host outer membrane; IEA:InterPro.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR000758; Enterovir_OMP.
DR   InterPro; IPR011250; OMP/PagP_b-brl.
DR   InterPro; IPR027385; OMP_b-brl.
DR   Pfam; PF13505; OMP_b-brl; 1.
DR   PRINTS; PR00316; ENTEROVIROMP.
DR   SUPFAM; SSF56925; SSF56925; 1.
DR   PROSITE; PS00694; ENT_VIR_OMP_1; 1.
DR   PROSITE; PS00695; ENT_VIR_OMP_2; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Membrane; Signal; Transmembrane;
KW   Transmembrane beta strand; Virulence.
FT   SIGNAL          1..26
FT                   /evidence="ECO:0000250"
FT   CHAIN           27..182
FT                   /note="Attachment invasion locus protein"
FT                   /id="PRO_0000020198"
FT   CONFLICT        7
FT                   /note="T -> I (in Ref. 1; AAB36601)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        43
FT                   /note="E -> D (in Ref. 1; AAB36601)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   182 AA;  20194 MW;  A8A973A6038D5488 CRC64;
     MVFMNKTLLV SSLIACLSIA SVNVYAEGES SISIGYAQSR VKEDGYKLDK NPRGFNLKYR
     YEFNNDWGVI GSFAQTRRGF EESVDGFKLI DGDFKYYSVT AGPVFRINEY VSLYGLLGAG
     HGKAKVSSIF GQSESRSKTS LAYGAGLQFN PHPNFVIDAS YEYSKLDDVK VGTWMLGAGY
     RF