ID   FACC1_RAT               Reviewed;         411 AA.
AC   Q6AY08;
DT   07-JUN-2005, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2004, sequence version 1.
DT   03-AUG-2022, entry version 96.
DE   RecName: Full=Flagellum-associated coiled-coil domain-containing protein 1 {ECO:0000250|UniProtKB:Q96Q35};
DE   AltName: Full=Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein homolog;
GN   Name=Flacc1 {ECO:0000250|UniProtKB:Q96Q35};
GN   Synonyms=Als2cr12 {ECO:0000312|RGD:1359362};
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q8BVM7}.
CC       Cytoplasmic granule {ECO:0000250|UniProtKB:Q8BVM7}. Cell projection,
CC       cilium, flagellum {ECO:0000250|UniProtKB:Q8BVM7}. Note=Expressed in the
CC       principal piece of the sperm tail, nearest the sperm head.
CC       {ECO:0000250|UniProtKB:Q8BVM7}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BC079241; AAH79241.1; -; mRNA.
DR   RefSeq; NP_001014123.1; NM_001014101.1.
DR   AlphaFoldDB; Q6AY08; -.
DR   SMR; Q6AY08; -.
DR   STRING; 10116.ENSRNOP00000034322; -.
DR   iPTMnet; Q6AY08; -.
DR   PhosphoSitePlus; Q6AY08; -.
DR   PaxDb; Q6AY08; -.
DR   PRIDE; Q6AY08; -.
DR   Ensembl; ENSRNOT00000038431; ENSRNOP00000034322; ENSRNOG00000024917.
DR   GeneID; 316413; -.
DR   KEGG; rno:316413; -.
DR   UCSC; RGD:1359362; rat.
DR   CTD; 130540; -.
DR   RGD; 1359362; Flacc1.
DR   eggNOG; ENOG502R2KT; Eukaryota.
DR   GeneTree; ENSGT00400000022323; -.
DR   HOGENOM; CLU_049696_0_0_1; -.
DR   InParanoid; Q6AY08; -.
DR   OMA; MEKEYKY; -.
DR   OrthoDB; 1374230at2759; -.
DR   PhylomeDB; Q6AY08; -.
DR   TreeFam; TF338239; -.
DR   PRO; PR:Q6AY08; -.
DR   Proteomes; UP000002494; Chromosome 9.
DR   Bgee; ENSRNOG00000024917; Expressed in testis and 13 other tissues.
DR   GO; GO:0005737; C:cytoplasm; ISS:UniProtKB.
DR   GO; GO:0031410; C:cytoplasmic vesicle; ISS:UniProtKB.
DR   GO; GO:0001520; C:outer dense fiber; ISS:UniProtKB.
DR   GO; GO:0035686; C:sperm fibrous sheath; IBA:GO_Central.
DR   GO; GO:0036126; C:sperm flagellum; ISS:UniProtKB.
DR   InterPro; IPR026674; FLACC1.
DR   PANTHER; PTHR21707; PTHR21707; 1.
PE   2: Evidence at transcript level;
KW   Acetylation; Cell projection; Cilium; Coiled coil; Cytoplasm; Flagellum;
KW   Reference proteome.
FT   CHAIN           1..411
FT                   /note="Flagellum-associated coiled-coil domain-containing
FT                   protein 1"
FT                   /id="PRO_0000064541"
FT   REGION          52..77
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          124..220
FT                   /evidence="ECO:0000255"
FT   COILED          278..328
FT                   /evidence="ECO:0000255"
FT   COILED          355..385
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        62..76
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         353
FT                   /note="N6-acetyllysine"
FT                   /evidence="ECO:0000250|UniProtKB:Q96Q35"
SQ   SEQUENCE   411 AA;  48491 MW;  22CBCC0BF8E9702D CRC64;
     MYPNPLIYCT CWDPWNLGPR KLIKTPHPLP KASIRKPIFP APISREPNYL LSQPAKSTAF
     PRDKAQSRKL EESNKAPSEV IEVSPGYKLV RNREQISVTL GDEMFSRKKH LESGILSKVK
     ISRSDIISDL EEQISELSAI IEQMNRDHQS AQKLLSNEMD LRCADMKQKF ETESRELKQT
     HKEQLEKLEN SYKETLKVEK AAAQEKLDEM GKEYKYLKNM FHMYQDSIYD EMEDKWSRRK
     AEWEKDEKME REKILLQQKH RITKKFELES EEEKRKMNES FSTVMENFTR EKEELIRQHN
     EDILQMQELR KAKEILEAEL RTQAVVLETL NTSLYHCQIE LQREKTMAGN LEKLFQTKLA
     EAEEKYKSTI QVLTEENNSL RQKVLTISTN EEIFEERSEK SSSASPNIYE S