ID   FACOS_HUMAN             Reviewed;         177 AA.
AC   Q96PS1;
DT   16-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 1.
DT   03-AUG-2022, entry version 114.
DE   RecName: Full=FANCD2 opposite strand protein;
DE   AltName: Full=Fanconi anemia group D2 protein opposite strand transcript protein;
GN   Name=FANCD2OS; Synonyms=C3orf24; ORFNames=HSD19;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Timmers C.D., Hejna J.A., Reifsteck C., Lucas L.W., Bruun D.A.,
RA   Thayer M.J., Taniguchi T., Olson S.B., D'Andrea A., Moses R.E., Grompe M.;
RL   Submitted (FEB-2000) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RA   Yang C.B., Miao S.Y., Zhang X.D., Qiao Y., Liang G., Wang L.F.;
RT   "A new spermatogenesis-related gene.";
RL   Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16641997; DOI=10.1038/nature04728;
RA   Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R., Buhay C.J.,
RA   Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P.,
RA   Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J., Jackson A.,
RA   Khan Z.M., Kovar-Smith C., Lewis L.R., Lozado R.J., Metzker M.L.,
RA   Milosavljevic A., Miner G.R., Morgan M.B., Nazareth L.V., Scott G.,
RA   Sodergren E., Song X.-Z., Steffen D., Wei S., Wheeler D.A., Wright M.W.,
RA   Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M.,
RA   Brown M.J., Chen G., Chen Z., Clendenning J., Clerc-Blankenburg K.P.,
RA   Chen R., Chen Z., Davis C., Delgado O., Dinh H.H., Dong W., Draper H.,
RA   Ernst S., Fu G., Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J.,
RA   Hao B., Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W.,
RA   Jackson L.R., Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B.,
RA   Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.-V., Okwuonu G.O.,
RA   Palmeiri A., Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B.,
RA   Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H.,
RA   Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J.,
RA   Wang J., Wang Q., Williams G.A., Wong G.K.-S., Yao Z., Zhang J., Zhang X.,
RA   Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H., Reinhardt R.,
RA   Naylor S.L., Yang H., Olson M., Weinstock G., Gibbs R.A.;
RT   "The DNA sequence, annotation and analysis of human chromosome 3.";
RL   Nature 440:1194-1198(2006).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
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DR   EMBL; AF230334; AAL05979.1; -; mRNA.
DR   EMBL; AY248899; AAP20050.1; -; mRNA.
DR   EMBL; AC034193; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BC028122; AAH28122.1; -; mRNA.
DR   CCDS; CCDS2596.1; -.
DR   RefSeq; NP_001158311.1; NM_001164839.1.
DR   RefSeq; NP_775743.1; NM_173472.1.
DR   RefSeq; XP_011531633.1; XM_011533331.2.
DR   AlphaFoldDB; Q96PS1; -.
DR   BioGRID; 125455; 25.
DR   STRING; 9606.ENSP00000429608; -.
DR   iPTMnet; Q96PS1; -.
DR   PhosphoSitePlus; Q96PS1; -.
DR   BioMuta; FANCD2OS; -.
DR   MassIVE; Q96PS1; -.
DR   PaxDb; Q96PS1; -.
DR   PRIDE; Q96PS1; -.
DR   ProteomicsDB; 77742; -.
DR   Antibodypedia; 53127; 66 antibodies from 14 providers.
DR   DNASU; 115795; -.
DR   Ensembl; ENST00000450660.3; ENSP00000429608.1; ENSG00000163705.13.
DR   Ensembl; ENST00000524279.1; ENSP00000429663.1; ENSG00000163705.13.
DR   GeneID; 115795; -.
DR   KEGG; hsa:115795; -.
DR   MANE-Select; ENST00000450660.3; ENSP00000429608.1; NM_001164839.2; NP_001158311.1.
DR   UCSC; uc003buz.3; human.
DR   CTD; 115795; -.
DR   DisGeNET; 115795; -.
DR   GeneCards; FANCD2OS; -.
DR   HGNC; HGNC:28623; FANCD2OS.
DR   HPA; ENSG00000163705; Tissue enriched (testis).
DR   MalaCards; FANCD2OS; -.
DR   neXtProt; NX_Q96PS1; -.
DR   OpenTargets; ENSG00000163705; -.
DR   PharmGKB; PA142672385; -.
DR   VEuPathDB; HostDB:ENSG00000163705; -.
DR   eggNOG; ENOG502S0QV; Eukaryota.
DR   GeneTree; ENSGT00390000000631; -.
DR   HOGENOM; CLU_1510145_0_0_1; -.
DR   InParanoid; Q96PS1; -.
DR   OMA; FRASHCF; -.
DR   OrthoDB; 1226555at2759; -.
DR   PhylomeDB; Q96PS1; -.
DR   TreeFam; TF337186; -.
DR   PathwayCommons; Q96PS1; -.
DR   SignaLink; Q96PS1; -.
DR   BioGRID-ORCS; 115795; 8 hits in 1058 CRISPR screens.
DR   ChiTaRS; FANCD2OS; human.
DR   GenomeRNAi; 115795; -.
DR   Pharos; Q96PS1; Tdark.
DR   PRO; PR:Q96PS1; -.
DR   Proteomes; UP000005640; Chromosome 3.
DR   RNAct; Q96PS1; protein.
DR   Bgee; ENSG00000163705; Expressed in left testis and 98 other tissues.
DR   ExpressionAtlas; Q96PS1; baseline and differential.
DR   Genevisible; Q96PS1; HS.
DR   InterPro; IPR027966; FANCD2OS.
DR   PANTHER; PTHR31036; PTHR31036; 1.
DR   Pfam; PF15124; FANCD2OS; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome.
FT   CHAIN           1..177
FT                   /note="FANCD2 opposite strand protein"
FT                   /id="PRO_0000235343"
SQ   SEQUENCE   177 AA;  20188 MW;  4D193F8362CB6BEB CRC64;
     MAGYQLWSPW TPLDESFQWL RHTTPTPSSK HPFKASPCFP HTPSDLEVQL CFQEVTLVLD
     SPFLESGVSP KLPCHTSELR TMNNKGLVRK PQPIRLSGVD SVFGRVITAQ PPKWTGTFRV
     SDKSAFCKII SREHQWPIGL KEPQIQMTVT MCKQMLRSIL LLYATYKKCT FALQHSK