FAD3C_SOYBN
ID FAD3C_SOYBN Reviewed; 453 AA.
AC P48621;
DT 01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1996, sequence version 1.
DT 03-AUG-2022, entry version 87.
DE RecName: Full=Omega-3 fatty acid desaturase, chloroplastic;
DE EC=1.14.19.-;
DE Flags: Precursor;
GN Name=FAD7;
OS Glycine max (Soybean) (Glycine hispida).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Glycine;
OC Glycine subgen. Soja.
OX NCBI_TaxID=3847;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC TISSUE=Seed;
RX PubMed=8029334; DOI=10.1104/pp.103.2.467;
RA Yadav N.S., Wierzbicki A., Aegerter M., Caster C.S., Perez-Grau L.,
RA Kinney A.J., Hitz W.D., Booth J.R. Jr., Schweiger B., Stecca K.L.,
RA Allen S.M., Blackwell M., Reiter R.S., Carlson T.J., Russell S.H.,
RA Feldmann K.A., Pierce J., Browse J.;
RT "Cloning of higher plant omega-3 fatty acid desaturases.";
RL Plant Physiol. 103:467-476(1993).
CC -!- FUNCTION: Chloroplast omega-3 fatty acid desaturase introduces the
CC third double bond in the biosynthesis of 16:3 and 18:3 fatty acids,
CC important constituents of plant membranes. It is thought to use
CC ferredoxin as an electron donor and to act on fatty acids esterified to
CC galactolipids, sulfolipids and phosphatidylglycerol.
CC -!- PATHWAY: Lipid metabolism; polyunsaturated fatty acid biosynthesis.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast membrane {ECO:0000305};
CC Peripheral membrane protein {ECO:0000305}.
CC -!- DOMAIN: The histidine box domains may contain the active site and/or be
CC involved in metal ion binding.
CC -!- SIMILARITY: Belongs to the fatty acid desaturase type 1 family.
CC {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; L22965; AAA61776.1; -; mRNA.
DR PIR; JQ2339; JQ2339.
DR AlphaFoldDB; P48621; -.
DR STRING; 3847.GLYMA18G43210.2; -.
DR PRIDE; P48621; -.
DR eggNOG; ENOG502QQQ2; Eukaryota.
DR HOGENOM; CLU_033094_1_0_1; -.
DR InParanoid; P48621; -.
DR UniPathway; UPA00658; -.
DR Proteomes; UP000008827; Unplaced.
DR Genevisible; P48621; GM.
DR GO; GO:0031969; C:chloroplast membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016717; F:oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water; IEA:InterPro.
DR GO; GO:0006636; P:unsaturated fatty acid biosynthetic process; IEA:UniProtKB-UniPathway.
DR InterPro; IPR005804; FA_desaturase_dom.
DR InterPro; IPR021863; FAS_N.
DR Pfam; PF11960; DUF3474; 1.
DR Pfam; PF00487; FA_desaturase; 1.
PE 2: Evidence at transcript level;
KW Chloroplast; Fatty acid biosynthesis; Fatty acid metabolism;
KW Lipid biosynthesis; Lipid metabolism; Membrane; Oxidoreductase; Plastid;
KW Reference proteome; Transit peptide.
FT TRANSIT 1..?
FT /note="Chloroplast"
FT /evidence="ECO:0000255"
FT CHAIN ?..453
FT /note="Omega-3 fatty acid desaturase, chloroplastic"
FT /id="PRO_0000007121"
FT MOTIF 171..175
FT /note="Histidine box-1"
FT MOTIF 207..211
FT /note="Histidine box-2"
FT MOTIF 374..378
FT /note="Histidine box-3"
SQ SEQUENCE 453 AA; 51362 MW; 9DC2FDB28522C018 CRC64;
MATWYHQKCG LKPLAPVIPR PRTGAALSST SRVEFLDTNK VVAGPKFQPL RCNLRERNWG
LKVSAPLRVA SIEEEQKSVD LTNGTNGVEH EKLPEFDPGA PPPFNLADIR AAIPKHCWVK
DPWRSMSYVV RDVIAVFGLA AAAAYLNNWL VWPLYWAAQG TMFWALFVLG HDCGHGSFSN
NSKLNSVVGH LLHSSILVPY HGWRISHRTH HQHHGHAEND ESWHPLPEKL FRSLDTVTRM
LRFTAPFPLL AFPVYLFSRS PGKTGSHFDP SSDLFVPNER KDVITSTACW AAMLGLLVGL
GFVMGPIQLL KLYGVPYVIF VMWLDLVTYL HHHGHEDKLP WYRGKEWSYL RGGLTTLDRD
YGWINNIHHD IGTHVIHHLF PQIPHYHLVE ATEAAKPVFG KYYREPKKSA APLPFHLIGE
IIRSFKTDHF VSDTGDVVYY QTDSKINGSS KLE
