ID   3MGH_EHRCJ              Reviewed;         189 AA.
AC   Q3YR73;
DT   12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT   27-SEP-2005, sequence version 1.
DT   25-MAY-2022, entry version 87.
DE   RecName: Full=Putative 3-methyladenine DNA glycosylase {ECO:0000255|HAMAP-Rule:MF_00527};
DE            EC=3.2.2.- {ECO:0000255|HAMAP-Rule:MF_00527};
GN   OrderedLocusNames=Ecaj_0750;
OS   Ehrlichia canis (strain Jake).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Anaplasmataceae; Ehrlichia.
OX   NCBI_TaxID=269484;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Jake;
RX   PubMed=16707693; DOI=10.1128/jb.01837-05;
RA   Mavromatis K., Doyle C.K., Lykidis A., Ivanova N., Francino M.P., Chain P.,
RA   Shin M., Malfatti S., Larimer F., Copeland A., Detter J.C., Land M.,
RA   Richardson P.M., Yu X.J., Walker D.H., McBride J.W., Kyrpides N.C.;
RT   "The genome of the obligately intracellular bacterium Ehrlichia canis
RT   reveals themes of complex membrane structure and immune evasion
RT   strategies.";
RL   J. Bacteriol. 188:4015-4023(2006).
CC   -!- SIMILARITY: Belongs to the DNA glycosylase MPG family.
CC       {ECO:0000255|HAMAP-Rule:MF_00527}.
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DR   EMBL; CP000107; AAZ68782.1; -; Genomic_DNA.
DR   RefSeq; WP_011304859.1; NC_007354.1.
DR   AlphaFoldDB; Q3YR73; -.
DR   SMR; Q3YR73; -.
DR   STRING; 269484.Ecaj_0750; -.
DR   EnsemblBacteria; AAZ68782; AAZ68782; Ecaj_0750.
DR   KEGG; ecn:Ecaj_0750; -.
DR   eggNOG; COG2094; Bacteria.
DR   HOGENOM; CLU_060471_4_1_5; -.
DR   OMA; LPWRWYL; -.
DR   OrthoDB; 1385409at2; -.
DR   Proteomes; UP000000435; Chromosome.
DR   GO; GO:0003905; F:alkylbase DNA N-glycosylase activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0006284; P:base-excision repair; IEA:InterPro.
DR   CDD; cd00540; AAG; 1.
DR   Gene3D; 3.10.300.10; -; 1.
DR   HAMAP; MF_00527; 3MGH; 1.
DR   InterPro; IPR011034; Formyl_transferase-like_C_sf.
DR   InterPro; IPR003180; MPG.
DR   InterPro; IPR036995; MPG_sf.
DR   PANTHER; PTHR10429; PTHR10429; 1.
DR   Pfam; PF02245; Pur_DNA_glyco; 1.
DR   SUPFAM; SSF50486; SSF50486; 1.
DR   TIGRFAMs; TIGR00567; 3mg; 1.
PE   3: Inferred from homology;
KW   DNA damage; DNA repair; Hydrolase; Reference proteome.
FT   CHAIN           1..189
FT                   /note="Putative 3-methyladenine DNA glycosylase"
FT                   /id="PRO_0000265016"
SQ   SEQUENCE   189 AA;  21645 MW;  26A680FE80F46763 CRC64;
     MQYNILKKSF YAQQSLDVAE KLLGKKLLFN KHQGIITETE AYIGHDDPAA HSSHGYTKRT
     SVMFGDPGFS YVYFIYGMYH CLNVVTEPRG FPAAVLIRGI VLLLEDQPNI IINGPGKLCK
     ILHITKEHNN IDMTQNYNFC ICNTGINIHN YICTPRIGIS RGKEKFWRFV VSDLTFLQHL
     KLENKVYSI