ID   AIM18_KLULA             Reviewed;         315 AA.
AC   Q6CWH8;
DT   05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 82.
DE   RecName: Full=Altered inheritance of mitochondria protein 18, mitochondrial;
DE   Flags: Precursor;
GN   Name=AIM18; Synonyms=FMP22; OrderedLocusNames=KLLA0B03982g;
OS   Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 /
OS   NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX   NCBI_TaxID=284590;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the AIM18/AIM46 family. {ECO:0000305}.
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DR   EMBL; CR382122; CAH02104.1; -; Genomic_DNA.
DR   RefSeq; XP_451711.1; XM_451711.1.
DR   AlphaFoldDB; Q6CWH8; -.
DR   SMR; Q6CWH8; -.
DR   STRING; 28985.XP_451711.1; -.
DR   EnsemblFungi; CAH02104; CAH02104; KLLA0_B03982g.
DR   GeneID; 2897270; -.
DR   KEGG; kla:KLLA0_B03982g; -.
DR   eggNOG; ENOG502RGD3; Eukaryota.
DR   HOGENOM; CLU_038840_0_0_1; -.
DR   InParanoid; Q6CWH8; -.
DR   OMA; LGIYVAN; -.
DR   Proteomes; UP000000598; Chromosome B.
DR   GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR   GO; GO:0016872; F:intramolecular lyase activity; IEA:InterPro.
DR   Gene3D; 3.50.70.10; -; 1.
DR   InterPro; IPR016087; Chalcone_isomerase.
DR   InterPro; IPR016088; Chalcone_isomerase_3-sand.
DR   InterPro; IPR036298; Chalcone_isomerase_sf.
DR   Pfam; PF16035; Chalcone_2; 1.
DR   SUPFAM; SSF54626; SSF54626; 1.
PE   3: Inferred from homology;
KW   Mitochondrion; Reference proteome; Transit peptide.
FT   TRANSIT         1..35
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           36..315
FT                   /note="Altered inheritance of mitochondria protein 18,
FT                   mitochondrial"
FT                   /id="PRO_0000399552"
SQ   SEQUENCE   315 AA;  34672 MW;  C237BA20CEAEA575 CRC64;
     MLRFTHVLNN GAKRSALSLG RSYLRGFGSM HGPRVAVSTL IKKDKKPNGF RGMLALFVGI
     GTLAVSGLST NLYNDQNVKE DPWKSVSVDK SIDPFPTELK APEFPISTEY VMLGFGIRSV
     TFISFKVYGL GIYAAKEDLG LIPKVLDSNF LSTAFIDFDS SKSHQENLKT ALDNPETSRI
     LINNLLDSGI RLVAKITPIR NTDFNHLKDG LVKSILGHPD SKKDEDRLTN GLQQLRDAFS
     RKGSVPKNND LLIELQANGY LQVSYFDRKT GESTTMGQVK ETLIGKLLFS QYLSGPKPLS
     PSTKDSVVSK LVTLA